Activity of the small molecule PLK1, 2, and 3 inhibitor BI 2536 in preclinical models of MM in the absence of the bone microenvironment. by Douglas W. McMillin (348456)

“…<p>(A) BI 2536 (0–80 nM; 72 hrs) was tested against a panel of MM cell lines by MTT assay, the majority having IC50 values <40 nM. …”

DSS-induced colitis mouse model. by William C. Reisdorf (6616148)

“…Experimental groups were: Sham = vehicle control (no DSS or other treatment, n = 6), DSS = DSS-only (n = 12), CsA = 10 mg/kg i.p. treatment (n = 6), EPHX2i = GSK1910364A 50 mg/kg orally, twice daily (n = 6). …”

Intense reelin IR neurons synthesize reelin whereas punctate reelin IR neurons are characterized by the presence of receptor-bound reelin. by Cecilia Gonzalez Campo (264260)

“…GST-RAP was used at 25, 40 and 50 µg/ml. A significant decrease of punctate reelin IR was observed with 40 and 50 µg/ml of GST-RAP (4.5±1.5% and 3.1±0.7%; n = 3 and 3) whereas no effect was detected with a concentration of 25 µg/ml compared to untreated (22.2±1.4% and 21.3±2.2%; n = 3 and 3; F_(3,8) = 45.7, ***P<0.001). …”

Clinical and virological profiles of D9 vaccine trial group. by Jodi K. Craigo (421284)

“…<p>(<b>A</b>) Eight EIAV-naïve ponies were vaccinated with 3×10³ TCID₅₀ D9 I.M. …”

Effect of the lytic enzyme PeiR on M1 growth <i>in vitro</i>. by Sinead C. Leahy (244590)

Effect of anisotropy. by Diarmuid J. Cahalane (233294)

The effect of inhibition on metabolically efficient information transfer. by Tomas Barta (8067509)

Effect of aerobic exercise on intramyocellular (IMCL) and intrahepatocellular lipids (IHCL). by Andrea Egger (107540)

“…<p><b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0070865#pone-0070865-g003" target="_blank"><b>Figure 3a</b></a></b> Individual IMCL and IHCL measurements before (pre) and after (post) a 2h-aerobic exercise at 50% VO_2max of each subject. …”

Analytical vs numerical evaluation of oscillatory solutions in the Gaussian-drift approximation. by Natalie Schieferstein (17996519)

“…Including the reset does not affect <i>μ</i>_max but leads to a decrease in <i>μ</i>_min (Eqs (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011886#pcbi.1011886.e181" target="_blank">50</a>) vs (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011886#pcbi.1011886.e172" target="_blank">43</a>)) and thus a decrease in network frequency. …”

Regulation of CD36 mRNA expression by tumor necrosis factor (TNF)α and adalimumab by Jean Frédéric Boyer (32017)

Intracellular perfusion of astrocyte with inhibitors of vesicular transport of ATP selectively affects slower purinergic EPSCs. by Ulyana Lalo (506296)

“…Note the decrease in the amplitude of slow sEPSCs recorded in the presence of AP3A and lack of changes in the fast sEPSC. …”

Serum dilution optimization. by Brian J. Pak (610752)

“…Dilutions of 1∶10 and 1∶20 generated the highest antibody signal with no differences between the two dilutions (<i>p</i> = 0.17), while a significant decrease in signal intensity was observed between 1∶20 and 1∶50 dilutions (<i>p</i><0.001). …”

Arrhenius and Eyring analysis of McLOV proteins. by Kaley K. El-Arab (733285)

“…In contrast 337-TF, has markedly increased enthalpies of activation (71 kJ/mole vs. ~50 KJ/mole) with a decrease in the entropic penalty (-44 J/mole*K vs. ~ -100 J/mole*K).…”

The effect of neutralizing endogenous TGF-β on RV replication. by Nicole Bedke (137686)

“…The fold-decrease in viral replication by the neutralizing antibody was plotted as a ratio of the TCID₅₀/ml of antibody-treated versus isotype controls. …”

Figure CSA-2 4.12 by CIMR project (7352015)

“…<div><br></div><div>These panels show a comparison of mean error between "perfect" (no added error) all IR sensor data (red) and IR + CIMR data (blue) for a 15-day period in January compared with a "truth" model dataset.…”

90 biotin-MNP streptavidin-response curve data by Gabrielle Moss (19742920)

“…<p dir="ltr">These data demonstrate 90 biotin-MNP 3rd harmonic phase (phi 3) as a function of streptavidin concentration (streptavidin-response curve) in 1.00x, 0.50x, 0.03x, 0.015x, 0.005x, and 0.00x PBS solutions. …”

Example time-course plots derived from the primary screen, followed to the right by the corresponding concentration-response curves. by Anton Simeonov (85099)

“…<p>(A, B) Non-fluorescent inhibitors, compounds 3 and 14; the decrease in fluorescence is inhibited at increasing compound concentrations while the starting fluorescence remains constant. …”

Expression of Liprin-α4 in RNAi lines. by Kathrin Kiok (210915)

“…<p>The control pSUPER contains the vector without the RNAi construct and knock-down lines contain the vector including the siRNA construct against Liprin-α4. (A) Liprin-α4 is 50% down regulated in 323 and it is decreased approximately 20% in RNAi line 847. …”

Spermatogonial germ cell proliferation in prepubescent males. by J. Kim Holloway (218875)

“…Arrowheads mark mitotic TUNEL-positive cells. Scale bar is 50 µm. Quantitation of the GCNA-1 labeled (M) and TUNEL-positive (N) cells reveals a statistically significant decrease in prospermatogonia, accompanied by an increase in apoptotic cells (asterisks).…”

Annealing temperature optimization of the primer droplet library. by Alexander Herrmann (20166)

“…Increasing the annealing temperature to 58°C only results in a decrease in amplicon yield.</p>…”