α-blocker decreasing pain. by Mingchao Li (720305)

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) by F. Anthony Romero (2452198)

“…Structure–activity relationship studies coupled with further structure-based design targeting the LPF shelf, BC loop, and KAc regions allowed us to significantly increase potency and selectivity, resulting in the identification of non-CNS penetrant <b>19</b> (GNE-781, TR-FRET IC₅₀ = 0.94 nM, BRET IC₅₀ = 6.2 nM; BRD4(1) IC₅₀ = 5100 nΜ) that maintained good in vivo PK properties in multiple species. …”

Kat60 lacking the MIT domain does not disassemble microtubules at low levels of accumulation in cells. by Kyle D. Grode (725568)

Inducible expression of Kat60 results in measurable microtubule disassembly in our single-cell assay. by Kyle D. Grode (725568)

Kat60 lacking the MIT domain disassembles microtubules at high levels of accumulation in cells. by Kyle D. Grode (725568)

Time dependent activation of the pulmonary inflammatory response. by Marc-Alexander Oestreich (13961375)

Tissue, days post-infection (dpi) and the top 10 most significant genes with increased and decreased expression with valid gene symbols for the response contrasts. by Gillian P. McHugo (8965919)

Proteins lower than 10 kDa from TE modulate mouse and human DC maturation and their allostimulatory capacity. by Cristian R. Falcón (671586)

Trauma-distant activation of inflammatory response regulators in the non-injured left lung. by Marc-Alexander Oestreich (13961375)

Inhibition of TMEM16A decreased SW620 cell migration and invasion. by Yujie Sui (549090)

The Non-Catalytic Domains of <i>Drosophila</i> Katanin Regulate Its Abundance and Microtubule-Disassembly Activity by Kyle D. Grode (725568)

Experimental groups. by Marc-Alexander Oestreich (13961375)

Praziquantel treatment does not alter SmLy6A and SmLy6B IgG₁ age distribution profiles, but does decrease antigen-specific IgG₁ reactivity. by Iain W. Chalmers (173561)

BT9 exhibits a dose- and time-dependent cytotoxic effect on medulloblastoma. by Zahra Motahari (6814013)

Inhibition of the mitochondrial fission decreases mtROS production. by Dong Ma (584680)

Image_10_A Temporal Diversity Analysis of Brazilian Begomoviruses in Tomato Reveals a Decrease in Species Richness between 2003 and 2016.tif by Tadeu Araujo Souza (9214526)

siRNA treatment decreases ADAMTS-1 nuclear pattern in MDA-MB-231 cells. by Suély V. Silva (3233223)

Decreased number of cilia in partially formed KV lumen. by Jeong-gyun Kim (4330168)

Shows the 5′ region and the exons of the <i>C3</i> gene in the vertical line and the three new SNPs that we found by sequencing. by Yonghui Wang (287491)

Nonmetric multidimensional scaling ordination of lichen plots at distances 10 m through 4000 m from the DMTS haul road in Cape Krusenstern National Monument, Alaska. by Peter N. Neitlich (4034300)

Subjects: