Several VPS-II genes are upregulated in a Δ<i>zur</i> mutant. by Shannon G. Murphy (11001965)

“…<p><b>(A)</b> A predicted Zur-binding site (<u>TGTTAT</u>GTT<u>ATAACA</u>) located approximately 200 bp upstream of the <i>verA</i> open reading frame was aligned with the <i>Vibrionacae</i> Zur binding consensus sequence [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009624#pgen.1009624.ref035" target="_blank">35</a>]. …”

Effects of bortezomib on OATP1B1-mediated [³H]pitavastatin and [³H]E₂17βG transport in HEK293-OATP1B1 cells and on [³H]pitavastatin accu... by Khondoker Alam (1443499)

Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis by Lan Zhang (90951)

“…Early mobilization decreased the incidence of ICU-acquired weakness (ICU-AW) at hospital discharge (three studies, 190 patients, relative risk (RR): 0.60, 95% confidence interval (CI) [0.40, 0.90]; <i>p</i> = 0.013, <i>I</i>^<i>2</i> = 0.0%), increased the number of patients who were able to stand (one study, 50 patients, 90% vs. 62%, <i>p</i> = 0.02), increased the number of ventilator-free days (six studies, 745 patients, standardized mean difference (SMD): 0.17, 95% CI [0.02, 0.31]; <i>p</i> = 0.023, <i>I</i>^<i>2</i> = 35.5%) during hospitalization, increased the distance the patient was able to walk unassisted (one study, 104 patients, 33.4 (0–91.4) meters vs. 0 (0–30.4) meters, <i>p</i> = 0.004) at hospital discharge, and increased the discharged-to-home rate (seven studies, 793 patients, RR: 1.16, 95% CI [1.00, 1.34]; <i>p</i> = 0.046). …”

Depletion of <i>Tg</i>RPI results in severe growth defects <i>in vitro</i> and <i>in vivo</i>. by Ningbo Xia (13584299)

Impaired development of the brain and iBAT of rarely alive adult <i>aP2-Drp1</i>^f/f mice. by Yuta Ibayashi (20404811)

VgrS senses Fe³⁺ depletion by its sensor region. by Li Wang (15202)

“…<p>(A) Fe³⁺ inhibits the autophosphorylation of full-length VgrS. …”

Recoded DENV2 has disrupted RNA structural elements and genetically stable attenuation. by Wei-Xin Chin (843752)

Supplementary Material for: Temporary Severe Neutropenia during Administration of Atezolizumab: A Novel Case Report by Kanno R. (15320458)

“…Here we describe a case of temporary severe neutropenia after atezolizumab monotherapy and its treatment course. …”

Only a Small Fraction of the Neuronal Population Participated in the Response to an Acoustic Stimulus at Any Instant by Tomáš Hromádka (74109)

“…<div><p>(A) The top panel shows the fractions of response bins per octave displaying no change (No), a significant (<i>p</i><0.01) increase (Inc), or a significant decrease (Dec) in the firing rate evoked by 30–40 dB tones (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0060016#s4" target="_blank">Materials and Methods</a> for details). …”

ARC POMC neurons express temperature-sensitive TRPV1 receptors. by Jae Hoon Jeong (215351)

A study of the abundance of species in grassland-to-pond transition zone and impermeable ground habitats by Helen Musulan (3119433)

“…To count the abundance of native and exotic herbaceous plants, surveyors used a 1.00m x 1.00m quadrat to visually inspect and sample individuals. …”

Supplementary Material for: Endovascular thrombectomy with or without bridging thrombolysis in acute ischemic stroke: A cost-effectiveness analysis by Morsi R.Z. (17739816)

“…At a willingness-to-pay threshold of $50,000 per QALY gained, the probabilities of EVT only to be cost-effective were 100%, 100%, and 99.3% over 90-day, 1-year, and 5-year time horizons. …”

Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model by Genmin Lu (5029949)

“…In edoxaban-anticoagulated rabbits, andexanet reduced anti-FXa activity by 82% (from 548±87 to 100±41 ng/ml; <i>P</i><0.0001), mean unbound edoxaban plasma concentration by ~80% (from 100±10 to 21±6 ng/ml; <i>P</i><0.0001), and blood loss by 80% vs. vehicle (adjusted for control, 2.6 vs. 12.9 g; <i>P</i> = 0.003). …”

Iron-VgrR binding disassociates VgrR-DNA and VgrR-VgrS interactions. by Li Wang (15202)

“…<p>(A) The amount of VgrR–P<i>tdvA</i> binding was decreased in iron-replete conditions. …”

The expression of pain receptors in <i>α</i>-GalA KO males frontal paws. by Jarmila Lakomá (152379)

“…The analysis of TRPM8 (Santa Cruz) expression (∼127 kDa) in the whole protein extract from skin of frontal paws showed the almost half expression decrease in protein expression of TRPM8 in case of α-GalA KO (n = 3) males when compared to WT (n = 3), p = 0.0518. …”

Incidence of lower extremity amputations in the diabetic compared with the non-diabetic population: A systematic review by Maria Narres (575779)

“…Study designs, statistical methods, definitions of major and minor amputations, as well as the methods to identify patients with diabetes differed greatly, explaining in part these considerable differences. Some studies found a decrease in incidence of LEA as well as relative risks over time. …”

Table_2_Genotypes of Pain and Analgesia in a Randomized Trial of Irritable Bowel Syndrome.XLSX by Jan Vollert (5099921)

“…Background<p>Irritable bowel syndrome (IBS) is a highly prevalent chronic pain disorder with multiple underlying mechanisms and few treatments that have been demonstrated to be effective in placebo controlled trials. …”

Table_1_Genotypes of Pain and Analgesia in a Randomized Trial of Irritable Bowel Syndrome.xlsx by Jan Vollert (5099921)

“…Background<p>Irritable bowel syndrome (IBS) is a highly prevalent chronic pain disorder with multiple underlying mechanisms and few treatments that have been demonstrated to be effective in placebo controlled trials. …”

Table 1_Survival assessment in extremely preterm neonates in a middle-income setting.docx by Maria J. Rodriguez-Sibaja (17456689)

“…Overall mortality decreased with increasing gestational age, from 100% (22/22) at <24.0 weeks of gestation to 87% (14/16), 42% (16/38), and 21% (11/52) at a gestational age of 25, 26, and 27 weeks, respectively. …”

Table 2_Survival assessment in extremely preterm neonates in a middle-income setting.docx by Maria J. Rodriguez-Sibaja (17456689)

“…Overall mortality decreased with increasing gestational age, from 100% (22/22) at <24.0 weeks of gestation to 87% (14/16), 42% (16/38), and 21% (11/52) at a gestational age of 25, 26, and 27 weeks, respectively. …”