The role of ERα in by Hongzhu Li (144792)

“…<b><i>D</i></b>, Knockdown of ERα reversed estrogen-decreased cell viability in WT-SMCs. The cells were transfected with siRNA ERα or siRNA C at 50 nM for 12 h following another 36 h treatment with estrogen (100 nM). * p<0.05 <i>vs</i>. siRNA C group; ^# p<0.05 <i>vs</i>. siRNA C+estrogen group. …”

DataSheet1_Real-World Management and Clinical Outcomes of Stroke Survivors With Atrial Fibrillation: A Population-Based Cohort in Spain.docx by Clara L. Rodríguez-Bernal (11829377)

“…Regarding temporal trends, management with OAC increased by 20%, with a decrease of 50% for APT during the study period. No treatment and OAC + APT remained relatively stable. …”

Table_1_Initial Report of a Phase I Study of LY2510924, Idarubicin, and Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia.DOCX by Prajwal Boddu (5780843)

“…Three and one complete responses were observed at dose-levels “0” and “1,” respectively; the overall response rate (ORR) was 36% (4 of 11 patients). A ≥ 50% decrease in CXCR4 mean fluorescence intensity was observed in 4 of 9 patients by flow cytometry, indicating incomplete suppression of CXCR4-receptor occupancy.…”

Table_1_Initial Report of a Phase I Study of LY2510924, Idarubicin, and Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia.DOCX by Prajwal Boddu (5780843)

“…Three and one complete responses were observed at dose-levels “0” and “1,” respectively; the overall response rate (ORR) was 36% (4 of 11 patients). A ≥ 50% decrease in CXCR4 mean fluorescence intensity was observed in 4 of 9 patients by flow cytometry, indicating incomplete suppression of CXCR4-receptor occupancy.…”

Data_Sheet_1_Temperature limits for storage of extended boar semen from the perspective of the sperm's energy status.zip by Heiko Henning (5692907)

“…Cluster analysis revealed that the main sperm subpopulation, i.e., sperm with moderate speed and linearity, decreased from 50 to 30% (P < 0.05) in favor of slow-moving spermatozoa (5°C) or spermatozoa with a hyperactivation-like motility pattern (10°C). …”

DataSheet1_Safety and effectiveness of HSK21542 for hemodialysis patients: a multiple ascending dose study.pdf by Mingming Pan (5576021)

“…Compared to the placebo, a significant decrease of the weekly mean Worst Itching Intensity Numerical Rating Scale was found in the HSK21542-0.30 μg/kg group (p = 0.046), but without significant improvement in the Skindex-16 score.…”

Data_Sheet_1_Duration of the effectiveness of nicotine electronic cigarettes on smoking cessation and reduction: Systematic review and meta-analysis.docx by Paul Vanderkam (13196394)

“…The reduction was defined as at least 50% of the initial consumption or by a decrease of daily mean cigarette consumption at the end of the intervention and follow-up periods.…”

Image_1_The Impact of Multimorbidity Burden, Frailty Risk Scoring, and 3-Directional Morphological Indices vs. Testing for CSF Responsiveness in Normal Pressure Hydrocephalus.JPEG by Shereen X. Y. Soon (9569062)

Figure 2 by Heidi de Wit (67655)

“…Inset shows cumulative vesicle distribution in the sub-membrane region within 0–100 nm. Grey line represents the vesicle distribution in the absence of Munc18-1 as shown before <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000126#pone.0000126-Toonen2" target="_blank">[24]</a>. …”

Response to NLC for 1 122 native plant species with significant null models. by Kaixuan Pan (11714457)

“…<p>3 species with a neutral (without a relationship, named ‘None’) response were omitted as not preferring any NLC. a-h, Response curves of plant species to NLC. i-l, Summary statistics of preferred NLCs. a, Summary of all 1 122 native plants responding to NLC (with percentages in parentheses). b-d, Response curves of species with decreasing (each magenta line indicates one species) (b), unimodal (each blue line indicates one species) (c) and increasing (each green line indicates one species) (d) relations with NLC. …”

The FRET and eCFP ratio of cpFLIPPi-6.4m between intestinal cells of <i>C</i>. <i>elegans</i> is similar. by Swayoma Banerjee (816022)

“…<p>(A) eCFP and FRET emission channels, respectively showing donor and non-corrected FRET emission after the donor is excited with the 445nm laser. …”

Other glycines substitutions that destabilize BH4-Bcl-2’s by Giovanni Monaco (452223)

“…Data points represent means ± SEM. * indicates a statistically significant difference from vehicle control.…”

Figure CSA-2 4.12 by CIMR project (7352015)

“…</div><div><br></div><div>It can be seen that both mean error and standard deviation decrease with the addition of CIMR data. …”

Data_Sheet_1_Secular Difference in Body Mass Index From 2014 to 2020 in Chinese Older Adults: A Time-Series Cross-Sectional Study.docx by Ying Jiang (5910)

“…</p>Materials and Methods<p>We analyzed 7 continuous survey years (2014–2020), including 50,192 Chinese aged participants (25,505 men and 24,687 women, aged 71.9 ± 6.1 years, age range: 65–99 years). …”

RSK and PDK1 contribute to Ca²⁺-induced force, MYPT1 and RLC₂₀ phosphorylation in α-toxin permeabilized rabbit pulmonary artery SM. by Mykhaylo Artamonov (389145)

“…<p>RSK inhibitor, BI-D1870 is without effect on the actomyosin ATPase. (A) RSK inhibitor, BI-D1870 (100nM), right shifted the pCa²⁺-force relationship and decreased the maximal force (milli-Newtons, mN) at each intracellular Ca²⁺ concentration (pCa) compared to the Control diluent, DMSO. …”

Bacterial reads, same specie. by Laurent Gautier (853)

“…Independent samples of 5, 10, 25, 50, 100, 200, or 300 random reads were used in each query and the distribution of the rank of the correct references in the list recorded; a rank of means that the correct reference was at the very top of the list. …”

Image5_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIFF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image1_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image2_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image4_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIFF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”