HIV-1 Nef Inhibits Protease Activity and Its Absence Alters Protein Content of Mature Viral Particles by Luiza M. Mendonça (584366)

“…Using in vitro assays, we observed that Nef is highly capable of inhibiting Protease activity. …”

Cell adhesion changes β-catenin distributions under Wnt stimulations. by Jiawen Chen (589546)

“…Given the truth that the mutant of Y654 reduces the binding affinity between cadherin and β-catenin and decrease the phosphorylation rate of Y142, we set the Y142 phosphorylation rate of Y654 mutant equals to 0.4, 0.2 and 0.1 of the original value in wild-type β-catenin <b>c)</b>. …”

Table_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.XLSX by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_3_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Supplementary Material for: Selective Serotonin Reuptake Inhibitors and Serotonin Noradrenaline Reuptake Inhibitors withdrawal changes DSM presentation of mental disorders: Results... by Cosci F. (4134769)

“…Using a new nosographic classification of withdrawal syndromes due to SSRI/SNRI decrease or discontinuation (by Chouinard and colleagues), we explored whether DSM is adequate to identify DSM disorders when withdrawal occurs. …”

Data_Sheet_2_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.pdf by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_4_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Dataset for: Vascular narrowing in pulmonary arterial hypertension is heterogeneous: rethinking resistance by Nina Rol (3929081)

“…Within each order the decrease in diameter of affected vessels is variable with an averaged diameter fraction of 50-70%. …”

Trilemma of life cycle carbon, employment, and costs of trucking industry's shift toward automation and electrification by Mandouri, Jafar

“…Autonomy and electrification combined could lead to a 50% decrease in emissions and 46% savings in life cycle costs. …”
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Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

Average changes in parameter trajectories. by Philippa J. Karoly (761618)

NMDA does not alter PPR but does potentiate postsynaptic responses to glycine. by Michelle L. Kloc (7359230)

“…Paired pulse ratio does not decrease after NMDA-induced potentiation. Top, average of 5 IPSCs from a single experiment before (black) and 5 min after NMDA (blue). …”

Table_1_Understanding Thermostability Factors of Barley Limit Dextrinase by Molecular Dynamics Simulations.DOCX by Juan Du (118107)

Reversal of pathology in I2S knockout (mucopolysaccharidosis II) mice after three IT-lumbar injections of I2S. by Pericles Calias (334957)

Image_2_Understanding Thermostability Factors of Barley Limit Dextrinase by Molecular Dynamics Simulations.tif by Juan Du (118107)

Combined M002 and irradiation to neuroblastoma xenografts. by Lauren A. Gillory (469462)

“…Once tumors reached 300 mm³, animals received an intra-tumoral injection of vehicle [PBS + 10% glycerol, 50μL (n=10)] or M002 virus [1 × 10⁴ PFU / 50μL (n=10)]. …”

MK-2206 induced cytotoxicity, inhibited proliferation and was able to overcome the protective effects of the tumor microenvironment. by Vijay Ramakrishnan (117159)

“…<p>When we cultured MM cell lines with indicated concentrations of MK-2206 for 48 hrs we observed dose dependent decrease in <b>A)</b> viability as observed by MTT assays and <b>B)</b> tritiated thymidine uptake indicative of inhibition of proliferation albeit with differences in the sensitivity of cell lines to MK-2206. …”

Macromolecular biosynthetic parameters and metabolic profile in different life stages of <i>Leishmania braziliensis</i>: Amastigotes as a functionally less active stage by Marlene Jara (774474)

Evidence of local mechanical control for bone formation and resorption. by Friederike A. Schulte (406501)

“…(B) Percentage increase in trabecular BV/TV in the loading and control group. (C) Mean SED at formation, quiescent and resorption sites expressed as percent difference from the mean (over all animals) quiescent SED within the first time interval. …”