Image_2_TMEM16A Inhibition Preserves Blood–Brain Barrier Integrity After Ischemic Stroke.TIF by Pin-yi Liu (7136123)

“…Furthermore, our mechanistic study showed that TMEM16A knockdown alleviated NF-κB activation and nuclear translocation, indicating that TMEM16A knockdown downregulated OGD/R-induced ICAM-1 expression in an NF-κB-dependent manner. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Mean ranks for comparison of a) MNCSE and b) MSE at temporal scales 1 to 15 for quantifying the dynamics of pathological with disease severity. by Imtiaz Awan (5233526)

Mean ranks for comparison of a) MNCSE and b) MSE at temporal scales 1 to 15 for quantifying the dynamics of pathological with disease severity. by Imtiaz Awan (5233526)

Mean ± SD values of the (a) MSE and (b) MNCSE computed from40 different WGN and 1/f noise signals. by Imtiaz Awan (5233526)

Mean percentage changes (95% CI) in total testosterone, SHBG and free testosterone (mITT analysis). by Chanel Avenant (409756)

TPX2 selectively regulates the levels of H4K16ac during G1-phase. by Gernot Neumayer (77179)

“…<p>(A) Depletion of TPX2 by siRNA in MCF7 cells causes a constitutive decrease in H4K16ac levels that correlates with the known increase in ionizing radiation-dependent (10 Gy) γ-H2AX levels <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0110994#pone.0110994-Neumayer2" target="_blank">[15]</a>. …”

Changes in the renin-angiotensin-aldosterone system in female mice with cardiac-specific null mutation of <i>Prdm16</i>. by Ji-One Kang (844616)

Subjects:

Predicting Vulnerabilities of North American Shorebirds to Climate Change by Hector Galbraith (636637)

Fructose-1,6-bisphosphate regulates expression of ECM and ECM-degrading proteins <i>in vitro</i>. by Henrique Bregolin Dias (3700603)

Distribution of mean scores of mental health problems by year of survey and SES. by Benti Geleta Buli (15417868)

The minimal data set 16. by Esete Habtemariam Fenta (9727779)

Mean ± SE of leaf litter mass lost in insecticide treatment and control litter bags under different fire severities after: a) six; and b) twelve months. by Sebastian Buckingham (724823)

Demographic, anthropometric, mobility, health, and cognitive characteristics of the participants (N = 50). by Sirinun Boripuntakul (13994171)

Effects of pioglitazone on expression distribution of CIDEC and PPAR-γ on VAT. by Bilal Haider Shamsi (628670)