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The mechanism on phosphorylation of Hsp20<sup>Ser16</sup> inhibit GA stress and ER stress during OGD/R
Published 2019“…However, ER Stress related protein contents were decreased in the WT and S16D groups compared with the MOCK and S16A groups (P < 0.05). …”
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Image 1_Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice.jpeg
Published 2025“…Overexpression of METTL16 led to an increase in overall m<sup>6</sup>A methylation levels, furthermore, overexpression of either METTL16 or MAT2A enhanced learning and memory in 5 × FAD mice, elevated the expression levels of postsynaptic density 95 (PSD95) and synaptophysin (Syp), increased dendritic spine density, and decreased the accumulation of Aβ<sub>1–42</sub> in the hippocampus. …”
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Image 2_Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice.jpg
Published 2025“…Overexpression of METTL16 led to an increase in overall m<sup>6</sup>A methylation levels, furthermore, overexpression of either METTL16 or MAT2A enhanced learning and memory in 5 × FAD mice, elevated the expression levels of postsynaptic density 95 (PSD95) and synaptophysin (Syp), increased dendritic spine density, and decreased the accumulation of Aβ<sub>1–42</sub> in the hippocampus. …”