Showing 641 - 660 results of 47,344 for search '(( 50 ((we decrease) OR (mean decrease)) ) OR ( 16 ((nn decrease) OR (a decrease)) ))', query time: 1.02s Refine Results
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    Image 1_Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice.jpeg by Huan Chen (6545)

    Published 2025
    “…Overexpression of METTL16 led to an increase in overall m<sup>6</sup>A methylation levels, furthermore, overexpression of either METTL16 or MAT2A enhanced learning and memory in 5 × FAD mice, elevated the expression levels of postsynaptic density 95 (PSD95) and synaptophysin (Syp), increased dendritic spine density, and decreased the accumulation of Aβ<sub>1–42</sub> in the hippocampus. …”
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    Image 2_Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice.jpg by Huan Chen (6545)

    Published 2025
    “…Overexpression of METTL16 led to an increase in overall m<sup>6</sup>A methylation levels, furthermore, overexpression of either METTL16 or MAT2A enhanced learning and memory in 5 × FAD mice, elevated the expression levels of postsynaptic density 95 (PSD95) and synaptophysin (Syp), increased dendritic spine density, and decreased the accumulation of Aβ<sub>1–42</sub> in the hippocampus. …”
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    GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

    Published 2021
    “…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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