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19241
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19242
Susceptibility to COPD: Differential Proteomic Profiling after Acute Smoking
Published 2014“…SerpinB3 and Uteroglobin decreased after acute smoke exposure in young non-susceptible individuals exclusively, whereas Peroxiredoxin I, S100A9, S100A8, ALDH3A1 (Aldehyde dehydrogenase 3A1) decreased both in young susceptible and non-susceptible individuals, changes being significantly different between groups for Uteroglobin with iTRAQ and for Serpin B3 with iTRAQ and ELISA measures. …”
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19243
Inhibition of Cdk5 Activity Attenuates Dendritic Spine Formation and Maturation
Published 2008“…</p> <p>(B) Inhibition of cdk5 activity did not affect the formation but decreased the maturation of dendritic spines on apical dendrites of <i>DNcdk5</i>-expressing granule cells, whereas <i>DNcdk5</i>-expressing neurons with aberrantly targeted basal dendrites (BasalDNcdk5) showed a decrease in both formation and maturation of dendritic spines. …”
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19244
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19245
Related to Fig 3.
Published 2025“…(<b>Q</b>) Tumor growth kinetics recorded a significantly higher growth of BT-474_ZFX<sup>OE</sup> (mean ± SEM, <i>n</i> = 5) than BT-474_VECT<sup>OE</sup> tumors. …”
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19246
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19247
S1 Appendix -
Published 2024“…The results show that: (1) the change in mixed energy and sectorial income shows a negative influence, while energy intensity (EI) and population have an increasing trend over the study period. (2) The EI effects of the industrial, agriculture and transport sectors are continuously rising, which is lowering the income potential of each sector. (3) The cumulative values for the industrial, agricultural, and transport sectors increased by 57.3, 5.3, and 79.7 during 2019. …”
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19248
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19249
The diagram of RNF5 inhibition on KSHV lytic replication and PEL tumorigenesis.
Published 2023“…In PEL cells with RNF5 silencing, loss, or inhibition (right), RNF5-mediated EphA3 and EphA4 ubiquitination and degradation are inhibited, and the levels of EphA3 and EphA4 are increased, probably facilitating dimerization and oligomerization, which decrease ERK and Akt activation and the expression of cell cycle CDK1 and hedgehog gene Smo, resulting in the inhibition of KSHV lytic replication and suppression of PEL growth.…”
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19250
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19251
Schematic representation of key responses to MERS-CoV related to outcome.
Published 2014“…Right panel: In the absence of recognition, the decrease in IRF 3 is associated to a decreased production of IL 12 and IFNγ. …”
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19252
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19253
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19254
Metascape pathway analysis on differentially expressed genes between progressive familial intrahepatic cholestasis (PFIC) and Alagille (ALGS) samples.
Published 2022“…B) There was no decreased ATF6 gene expression in PFIC (n = 5) and ALGS (n = 5) livers compared to pNormal livers (n = 9) (p = 0.07 and p = 0.5 respectively).…”
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19255
<i>In vivo</i> dynamic near-infrared fluorescent imaging of A-431 tumor models.
Published 2012“…On day 4, 8, 12 (after As<sub>2</sub>O<sub>3</sub> treatment), the signal intensity of EGF-Cy5.5 uptake by control group (0 mg/kg/day As<sub>2</sub>O<sub>3</sub>) gradually increased, while the intensities in other three groups with different concentrations (0.5 mg/kg/day, 2.5 mg/kg/day, 5.0 mg/kg/day) of As<sub>2</sub>O<sub>3</sub> treatment gradually decreased (<i>p</i><0.05). …”
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19256
Hsc70 is critical for cancer cell survival.
Published 2014“…<p>(A) Knockdown of Hsc70 decreased cancer cell viability. …”
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19257
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19258
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19259
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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19260
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”