An mRNA hairpin formed between the <i>sigG</i> leader sequence and RBS significantly decreases P_<i>sigG</i><i>-lacZ</i> translation. by Elizabeth B. Mearls (5150810)

“…In these transcriptional reporters, <i>lacZ</i> is separated from the <i>sigG</i> RBS by a spacer and provided with an engineered RBS. <b>(E)</b> Mutations that weaken/eliminate or strengthen the <i>sigG</i> RBS-hairpin increase or decrease P_<i>sigG</i><i>-lacZ</i> expression, respectively. …”

Tissue repair Tregs are reduced in target tissues and lymphoid organs during acute <i>T</i>. <i>cruzi</i> infection. by Santiago Boccardo (5927954)

IL-33 supplementation fails to prevent trTreg reduction in established <i>T</i>. <i>cruzi</i> infection. by Santiago Boccardo (5927954)

Serum uric acid levels in patients with Parkinson’s disease: A meta-analysis by Min Wen (3549752)

“…Analyses were performed by using Review Manager 5.3 and Stata 11.0.</p><p>Results</p><p>Thirteen studies with a total of 4646 participants (2379 PD patients and 2267 controls) were included in this meta-analysis. …”

Downstream molecular effects of knockdown of the expression of 5-HT_1B and 5-HT_1D receptors, on invasion and proliferation biomarkers in PaCa cells. by Nilgun Gurbuz (623605)

“…<p>(<b>A–B</b>) The effect of siRNAs-mediated 5-HT_1B and 5-HT_1D receptors down-regulation on β1 integrin/ECM-mediated downstream signaling in PANC-1 (A) and MIAPaCa-2 cells (B). …”

Domain architecture of DLAR and PTP99A RPTPs. by Lalima L. Madan (205695)

“…The numbers in red refer to the amino acid numbering used for the models in the Molecular Dynamics Simulations. (Also listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0024766#pone.0024766.s010" target="_blank">Table S5</a>) B: Modulatory effects of the catalytically inactive D2 domain on the activity of the D1 domain of DLAR and PTP99A. …”

Table 5_Effects of extracorporeal carbon dioxide removal in facilitating ultra-protective ventilation strategies for patients with acute respiratory distress syndrome: a systematic... by Weifeng Zhen (12969341)

“…All analyses were performed using a random-effects model. Sensitivity and subgroup analyses were conducted to further explore the findings.…”

Severity of anaemia status among pregnant women. by Donatus Nbonibe Abaane (15909683)

“…At 36 weeks, AIP prevalence was 44.8% (95%CI:39.2, 50.4) using a cut-off of 11.0g/dl. At p<0.05, registering after the first trimester (AOR = 1.87, 95%CI: 1.17, 2.98, P = 0.009) and at a regional hospital (AOR = 2.25, 95%CI: 1.02, 4.98, P = 0.044) were associated with increased odds of AIP but registering at a private hospital (AOR = 0.32, 95%CI: 0.11, 0.92, P = 0.035) was associated with decreased odds of AIP at booking. …”

Determination of membrane fluidity in terms of Fluorescence Anisotropy (FA) and T cell stimulating ability of normal, infected and liposome treated infected MΦ. by Koushik Roy (193484)

Induction of IL-17A production during <i>C. neoformans</i> strain H99γ infection requires IFN-γR expression. by Karen L. Wozniak (229721)

“…A. Asterisks (*) indicate where significant decreases in CFU were observed in IFN-γR ^−/− mice compared to wild-type BALB/c mice (<i>P</i><0.01). …”

Table5_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.csv by Alexis R. Steinmetz (18573319)

Expression of proteins associated with AD is altered by eIF4A inhibition. by Andrew Bottley (361376)

“…Significant differences (p≤0.05 by t-test) are indicated by asterisks. <b>C</b>. Secreted A-beta levels in the medium of 9×10⁵ SH-SY5Y cells were assayed by ELISA 24 hours following treatment with 10 µM hippuristanol (+), demonstrating a modest but reproducible decrease in comparison to control cells (−). …”

Two featured series of rRNA-derived RNA fragments (rRFs) constitute a novel class of small RNAs by Ze Chen (38181)

“…In addition, the RNAi knockdown resulted in a significant decrease of H1299 cells in the G2 phase of the cell cycle. …”

Seroepidemiology of Human Bocaviruses 1 and 2 in China by Yexia Hao (731937)

“…Highest seroprevalence was observed in 3–5-year-olds. The seroprevalence of HBoV1 was significantly decreased between 10–13-year-olds (80.3%) and 14–20-year-olds (62.3%, <i>p</i>< 0.05). …”

Data_Sheet_1_DNA Methylation Can Mediate Local Adaptation and Response to Climate Change in the Clonal Plant Fragaria vesca: Evidence From a European-Scale Reciprocal Transplant Ex... by Iris Sammarco (12158502)

“…Here, we assessed whether epigenetic mechanisms, DNA methylation in particular, enable for local adaptation and response to increased and/or decreased temperature of natural populations of a clonal plant, Fragaria vesca (wild strawberry). …”

Table2_Time Series Transcriptomic Analysis by RNA Sequencing Reveals a Key Role of PI3K in Sepsis-Induced Myocardial Injury in Mice.DOCX by Xiao Yan (641696)

“…CLP surgery resulted in a significant decrease of animal survival rate and left ventricle contractile function, and an increase in cardiac dilation and infiltration of proinflammatory cells including Mac-2⁺ macrophages in a time-dependent manner. …”

Table1_Time Series Transcriptomic Analysis by RNA Sequencing Reveals a Key Role of PI3K in Sepsis-Induced Myocardial Injury in Mice.DOCX by Xiao Yan (641696)

“…CLP surgery resulted in a significant decrease of animal survival rate and left ventricle contractile function, and an increase in cardiac dilation and infiltration of proinflammatory cells including Mac-2⁺ macrophages in a time-dependent manner. …”

Image1_Time Series Transcriptomic Analysis by RNA Sequencing Reveals a Key Role of PI3K in Sepsis-Induced Myocardial Injury in Mice.JPEG by Xiao Yan (641696)

“…CLP surgery resulted in a significant decrease of animal survival rate and left ventricle contractile function, and an increase in cardiac dilation and infiltration of proinflammatory cells including Mac-2⁺ macrophages in a time-dependent manner. …”

IFN-γ limits trTreg expansion both <i>in vitro</i> after IL-33 stimulation and <i>in vivo</i> during <i>T</i>. <i>cruzi</i> infection. by Santiago Boccardo (5927954)

Increased tumor uptake upon doxorubicin treatment using [¹¹C]-AnxA5-ST but not [¹¹C]-mTrx-GFP-ST. by Qing Cheng (145897)

“…Note the similar uptake of [¹¹C]-AnxA5-ST and [¹¹C]-mTrx-GFP-ST in untreated mice, due to the non-specific EPR effect, while upon doxorubicin treatment an increase in [¹¹C]-AnxA5-ST uptake was seen in contrast to a non-statistically significant tendency to decrease of [¹¹C]-mTrx-GFP-ST. …”