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19561
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19562
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19563
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19564
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19570
Supplementary Material for: Increased Quinolone-Resistant Mutations of gyrA and parC Genes after Pouchitis Treatment with Ciprofloxacin
Published 2020“…We successfully quantified mutation rates at <i>gyrA</i> 83 and 87, and at <i>parC</i> 84, all of which were significantly higher in samples from CFX-treated patients (70, 84, and 38%) than from CFX-untreated patients (13, 11, and 5%). …”
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19571
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19572
Characterization of 39 independent isolated mutants with increased frameshifting activity caused by increased geranylation activity following localized mutagenesis of the <i>mnmH</...
Published 2016“…All these mutants have increased +1 frameshifting activity (data not shown), which is a caused by increased geranylation of tRNA. We did not observe a simple correlation between ability to suppress a +1 frameshift mutation to the level of cmnm<sup>5</sup>ges<sup>2</sup>UpU, which might not be expect, since induction of frameshifting is complex although partly dependent on a decreased level of charged Gln- [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0153488#pone.0153488.ref004" target="_blank">4</a>]. …”
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19573
<i>Drosophila</i> Spidey/Kar Regulates Oenocyte Growth via PI3-Kinase Signaling
Published 2016“…Several enzymes of fatty acid, triglyceride and hydrocarbon metabolism are required in oenocytes primarily for lipid droplet induction rather than for cell growth. In contrast, a very long chain fatty-acyl-CoA reductase (FarO) and a putative lipid dehydrogenase/reductase (Spidey, also known as Kar) not only promote lipid droplet induction but also inhibit oenocyte growth. …”
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19574
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19575
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19576
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19577
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19578
Distinct interactions of Sox5 and Sox10 in fate specification of pigment cells in medaka and zebrafish - Fig 2
Published 2018“…<p><b>Reductions in melanoblast and iridoblast specification in <i>sox10a</i> mutants were partially rescued by loss of <i>sox5</i></b>. …”
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19579
Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes
Published 2021“…Long QT syndrome type-3 (LQT3) is a congenital form of VA caused by cardiac sodium channel (I<sub>NaL</sub>) SCN5A mutations that prolongs cardiac action potential (AP) and enhances I<sub>NaL</sub> current. …”
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19580
SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells
Published 2016“…Conversely, overexpression of SPARC increased TGFBI deposition. A SPARC-YFP fusion construct expressed by the Met5a cell line co-localized with TGFBI in the cell-derived ECM. …”