Omigapil Treatment Decreases Fibrosis and Improves Respiratory Rate in dy^2J Mouse Model of Congenital Muscular Dystrophy by Qing Yu (337275)

“…<div><p>Introduction</p><p>Congenital muscular dystrophy is a distinct group of diseases presenting with weakness in infancy or childhood and no current therapy. …”

ABCA1 mRNA stimulated by cAMP decreases in J774 macrophages following CER-001 and HDL3 incubation. by Claudine Tardy (555707)

3-aminobenzamide decreased nuclear SIRT1 expression without modifying its activity, demonstrating basal SIRT1 activity increase. by Cindy Gueguen (526035)

Image 1_Decreased activity in zebrafish larvae exposed to glyphosate-based herbicides during development—potential mediation by glucocorticoid receptor.pdf by S. Spulber (19335583)

“…Taken together, our data indicate that developmental exposure to GBH has more pronounced effects than GLY on behavior at 5 dpf, and that interference with GR-mediated signaling may have a relevant contribution.…”

Image 2_Decreased activity in zebrafish larvae exposed to glyphosate-based herbicides during development—potential mediation by glucocorticoid receptor.pdf by S. Spulber (19335583)

“…Taken together, our data indicate that developmental exposure to GBH has more pronounced effects than GLY on behavior at 5 dpf, and that interference with GR-mediated signaling may have a relevant contribution.…”

Berenil treatment decreases the percentage of CD25⁺ and FoxP3⁺ cells in the spleens of infected mice. by Shiby Kuriakose (121471)

Manganase²⁺ stimulation decreases association of ADAM17 to β1 integrin and leads to increased ADAM17 activity. by Pal Gooz (330154)

Blocking CD4, integrins, and lectins simultaneously significantly decreased DC binding and uptake of both free and complement opsonized HIV-1. by Veronica Tjomsland (210021)

Kinetic Insights into Ammonia Decomposition over Rhodium: A Combined Experimental, Modeling, and Theoretical Study by Fanggang Zhang (22312742)

“…Ammonia decomposition over rhodium (Rh) catalysts was investigated across a wide range of pressures (0.5–5 bar) to gain kinetic insights relevant to hydrogen generation applications. …”

Silencing GRK2 and GRK3 attenuate C3aR desensitization but GRK5 and GRK6 do not. by Qiang Guo (218747)

“…<p>(A) shRNA control, (B) GRK2, (C) GRK3, (D) GRK5 and (E) GRK6 KD cells were loaded with Indo-1 (1 µM), stimulated with C3a (100 nM) for 5 min and intracellular Ca²⁺ mobilization was determined (black solid lines). …”

KO of <i>grp-1</i>, a GEF that stimulates Arf and PIP5K/PPK-1 to increase production of PIP2 substrate for the IIS cascade, provides neuroprotection. by Nazila Tehrani (665802)

“…<p>Left: a histogram showing a decrease in neurodegeneration upon KO of <i>grp-1</i> (a second independent cross gave very similar distribution, not shown) **: p<0.05; ***: p<0.01. …”

Th2 cytokines and IgE were decreased in G-1-treated BALB/c mice compared to non-treated controls. by Masamichi Itoga (706167)

The pathogenicity of <i>Radopholus similis</i> to tomato plants is decreased significantly after soaking with <i>Rs-crt</i> dsRNA. by Yu Li (183836)

Effect of cholinergic antagonists on CA3-CA1 synchronous epileptiform discharges induced in synaptic blockers aCSF. by Olha Zapukhliak (10297334)

“…(B) Application of d-tubocurarine blocks CA3-CA1 synchronous epileptiform discharges: (3) burst of discharges in synaptic blockers aCSF, (4) reduction of the discharges after tubocurarine application, (5) epileptiform discharges decrease under tubocurarine application.…”

MR sequences during supine bicycle exercise-induced stress protocol. by Laurence Bal-Theoleyre (2839193)

Early HCV infection enhanced cell survival signaling pathways associated with TGF-β in hepatocytes while phosphorylated Gab1 decreased. by Da-eun Nam (18927946)

Strains carrying different <i>ELP3</i> mutant alleles show decreased telomeric gene silencing and increased HU sensitivity. by Changchun Chen (139128)

Expression of SPDEF in TRAMP C2 prostate adenocarcinoma cells decreased cell growth, reduced migration and colony formation on soft agar. by Xin-Hua Cheng (154368)

“…<p><b>A</b>. qRT-PCR shows that <i>SPDEF</i> mRNA is increased in SPDEF OE cells (left panel). …”

Significantly decreased levels of CD4⁺CD25⁺ Treg cells in arthropathic Tax transgenic mice. by Takeo Ohsugi (225723)

“…(B) The majority of CD4⁺CD25⁺ T cells in non-transgenic mice expressed a high level of Foxp3 (81.2±1.4%), whereas half of CD4⁺CD25⁺ T cells in arthropathic Tax transgenic mice did not express Foxp3 (50.2±5.2%) (n = 6 per group), *** <i>P</i><0.001. …”

Wounds treated with sDll4-Fc have increased vascular density but decreased vascular maturation in direct proportion to the dosage level. by Alexandre Trindade (187498)

“…C,D,E) Representative anti-PECAM and anti-SMA immunofluorescence images of neo-vasculature in granulation tissue of wounds treated with (D) 0,05 mg/kg or (E) 2,5 mg/kg compared with control mice injected with PBS (C), in days 2, 4 and 6. sDll4-Fc therapy leads to decreased smooth muscle cell recruitment and increased vascular density that is directly proportional to the administered dosage. * In graphics represents p<0,05.…”