Fomepizole treatment decreases the NAD(H) pool, impairs ATP production, and enhances ribosomal targeting antibiotic efficacy. by Hansol Im (14803255)

Extensive lipid accumulation and proteins loss explains the decreased sinking velocity in starving <i>Phaeodactylum tricornutum.</i> by Yanqi Wu (489316)

VEGF and sFlt-1 mutants exhibit changes in stem cell marker gene expression by RT-qPCR. by Christopher R. Schlieve (3179439)

“…<p>(A) VEGF mutants demonstrated 0.55-fold reduction in Lgr5 expression compared to littermates (*p = 0.04). …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Video_2_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.AVI by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Video_3_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.AVI by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Image_2_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.TIF by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Image_1_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.TIF by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Video_1_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.AVI by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Mitochondrial dysfunction in sIBM patients. by Yoshitsugu Oikawa (9721356)

Mean probability of reporting a specific health status in non-hypertensive and hypertensive patients, with and without related medication, while excluding the effects of other fact... by Jesús Martín-Fernández (406234)

Treatment of filarial infection is associated with decreased F_o of antigen – specific Th2 subsets. by Rajamanickam Anuradha (129298)

Enhanced Nrf2 activity decreases lipid clearance rate and VLDL secretion in Keap1-KD mice. by Jialin Xu (40952)

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology by Laurence J. Howe (5579186)

“…Where evidence was found of genetic overlap, we used bidirectional Mendelian randomization (MR) to test the hypothesis that genetic liability to nsCL/P is causally related to implicated facial phenotypes. Across 5,804 individuals of European ancestry from two studies, we found strong evidence, using PRS, of genetic overlap between nsCL/P and philtrum width; a 1 S.D. increase in nsCL/P PRS was associated with a 0.10 mm decrease in philtrum width (95% C.I. 0.054, 0.146; P = 2x10^-5). …”

VEGF overexpression in OU culture increased OU size and altered stem/progenitor cell gene expression. by Christopher R. Schlieve (3179439)

“…(C) Significant increase in Bmi1 and Atoh1 expression and decrease in EphB2 expression was observed in doxycycline-treated VEGF OU compared to controls at 5 days (*p<0.05). …”

CK1δ-specific kinase activity in HT1080 cells is decreased after activation of Chk1. by Joachim Bischof (189845)