DataSheet7_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.ZIP by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

DataSheet3_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.ZIP by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

Table2_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.DOCX by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

Kinetic and equilibrium constants for binding of WT and mutant FVIII-C2 proteins to BO2C11. by Jasper C. Lin (685807)

“…The kinetic range for the Biacore T100 is: k_a constants from ~10³–10⁷ M^-1s^-1; k_d constants from ~10^-5–0.5 s^-1. …”

Over-expression of DN VPS4 in HEK293T cells leads to increased extracellular α-synuclein and parallel decrease in lysosome. by Takafumi Hasegawa (18204)

“…Each fraction was verified by the presence of a specific marker protein: LAMP-1 (late endosome and lysosome), Rab5 (early endosome), Rab11 (recycling endosome), Hsp90 (cytosol), and BSA (culture medium). …”

Binding of BDD-FVIII muteins to VWF (A-B) and to BO2C11 (C-G). by Jasper C. Lin (685807)

“…This mutein showed a ~100X faster off-rate and a 28-fold decreased affinity for BO2C11-Fab compared to WT-BDD-FVIII. …”

Differential expression patterns and functional gene groups associated with SARS-CoV-2 viral load across serially collected samples. by Vasanthi Avadhanula (259546)

Rb fraction decreases KA-induced loss of hippocampal GAD67+ interneurons during chronic period after KA injection. by Kangning Xu (589825)

Dose-dependent increase in NREM sleep and decrease in wakefulness by <i>p</i>.<i>o</i>. administration of TEG in mice. by Mahesh K. Kaushik (3753871)

“…<p>(A, B) Typical examples of EEG delta power (0.5–4 Hz), EMG integral, and hypnograms of a mouse after <i>p</i>.…”

FAK kinase-inhibition decrease clonogenic PDAC growth <i>in vitro</i> and inhibits tumor growth <i>in vivo</i>. by Asma Begum (4236649)

A combined algorithm to distinguish between IB and NC models based on the differences in binding kinetics and DynR temporal evolution. by Federico Sevlever (8934533)

“…In Examples 2 to 7, the fits are both bad (2, 3, 6) or both good (4, 5, 7), so <b><i>C</i></b> does not allow a decision and further analysis is needed. …”

Movement of the shaking codend across five flow velocities from 1.0 to 1.8 kt. by Vang Y. Nguyen (14492737)

Multicenter Phase 2 Trial of Sirolimus for Tuberous Sclerosis: Kidney Angiomyolipomas and Other Tumors Regress and VEGF- D Levels Decrease by Sandra L. Dabora (206838)

“…We observed regression of brain tumors (SEGAs) in 7/11 cases (26% mean decrease in diameter), regression of liver angiomyolipomas in 4/5 cases (32.1% mean decrease in longest diameter), subjective improvement in facial angiofibromas in 57%, and stable lung function in women with TSC/LAM (n = 15). …”

DataSheet1_Deciphering colorectal cancer radioresistance and immune microrenvironment: unraveling the role of EIF5A through single-cell RNA sequencing and machine learning.docx by Yaqi Zhong (19526857)

“…In vivo experiments showed that EIF5A knockdown led to increased infiltration of CD8+ T cells and M1 macrophages, and decreased M2 macrophages and Tregs following radiation therapy, thereby enhancing the radiotherapy response.…”

Supplementary Material for: The Impact of the SARS-CoV-2 (COVID-19) Pandemic on Gastroenterology Training by Pisani A. (10713897)

“…<b><i>Introduction:</i></b> The SARS-CoV-2 (COVID-19) pandemic has brought about a radical change in our working patterns. …”

SNPs that distinguish the 7 SARS-CoV-2 variants and used as targets for QUILLS assay primers. by Timothy Carroll (3762841)

Re-expression of hSulf-1 in cancer cells decreased the p-VEGFR2^Tyr1175 levels. by Weidan Ji (210360)

<i>In situ</i> hybridization of <i>Ramp2</i> in e13.5 placentas reveals robust expression in the labyrinth layer. by Mahita Kadmiel (4262311)

Viral measurements do not predict off-ART rebound in d4 and d5 ART RMs. by Brandon F. Keele (7450001)

(a) Associations Between mAge Acceleration and Visual Attention to the Eyes. by Keiko Ochiai (21453423)