Silencing GRK2 and GRK3 attenuate C3aR desensitization but GRK5 and GRK6 do not. by Qiang Guo (218747)

“…<p>(A) shRNA control, (B) GRK2, (C) GRK3, (D) GRK5 and (E) GRK6 KD cells were loaded with Indo-1 (1 µM), stimulated with C3a (100 nM) for 5 min and intracellular Ca²⁺ mobilization was determined (black solid lines). …”

Table_5_Effect of high-dose Spirulina supplementation on hospitalized adults with COVID-19: a randomized controlled trial.docx by Mohammad Reza Aghasadeghi (9524778)

“…This study aimed to evaluate the efficacy and safety of high-dose Spirulina platensis for SARS-CoV-2 infection.</p>Study Design<p>We conducted a randomized, controlled, open-label trial involving 189 patients with COVID-19 who were randomly assigned in a 1:1 ratio to an experimental group that received 15.2g of Spirulina supplement plus standard treatment (44 non-intensive care unit (non-ICU) and 47 ICU), or to a control group that received standard treatment alone (46 non-ICU and 52 ICU). …”

Multiple homologs of 16p12.1 genes contribute to neurodevelopmental defects in <i>Drosophila melanogaster</i> and <i>X</i>. <i>laevis</i>. by Lucilla Pizzo (2735491)

“…<i>laevis</i> represents controls injected with the highest amount of morpholino (50 ng, see <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009112#pgen.1009112.s005" target="_blank">S5 Fig</a></b>). …”

TNAP-I reduces oxygen-glucose deprivation (OGD)-induced decreases in fEPSP recordings from CD73^−/− mice. by Dali Zhang (318168)

Decreased expression of lipid absorption and increased expression of lipid secretion markers in <i>Ces1/Es-x^−/−</i> mice. by Ariel D. Quiroga (300200)

Median confidence factor at the end of the simulation decreases as war costs increase (line represents the median of 200 simulations for each level of war costs). by Dominic D. P. Johnson (215994)

“…Note, however, that this decrease would be offset by altering other settings of the model, such as increasing the attack threshold, <i>w</i>, above 0.5, or allowing the spoils of victory to exceed the losses of defeat, instead of the current setup in which there is a zero-sum gain or loss of a province.…”

AtRALF1 labeled with chemiluminescent acridinium (acriAtRALF1) shows decreased specific binding in <i>bak1</i> mutants. by Keini Dressano (4512241)

Data_Sheet_1_A five-year observational prospective mono-center study of the efficacy of alemtuzumab in a real-world cohort of patients with multiple sclerosis.PDF by Sofia Sandgren (17017017)

“…/mL (IQR 285.4) (p = 0.05); serum month 24: 6.7 pg/mL (IQR 4.7) (p < 0.01); serum month 60: 7.2 pg/mL (IQR 4.7) (p < 0.01)], compared to baseline [CSF: 1014 pg/mL (IQR 2832.5); serum 8.6 pg/mL (IQR 17.4)].</p>Conclusion<p>In this real-world mono-center population, we observed a progression-free survival of 69%, cumulative NEDA-3 of 33%, and reduced NfL levels, over a five-year follow-up. …”

Image1_Liquid platelet-rich fibrin produced via horizontal centrifugation decreases the inflammatory response and promotes chondrocyte regeneration in vitro.JPEG by Huimin Li (126429)

ET-26 hydrochloride (ET-26 HCl) has similar hemodynamic stability to that of etomidate in normal and uncontrolled hemorrhagic shock (UHS) rats by Bin Wang (30851)

“…</p><p>Methods</p><p>50% effective dose (ED₅₀) and 50% lethal dose (LD₅₀) were determined after single bolus doses of propofol, etomidate, or ET-26 HCl using the Bliss method and the up and down method, respectively. …”

DataSheet1_The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis.docx by Sandra Torres (3361256)

2‑Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) by Ariel L. Burgio (15069256)

“…To develop more potent compounds, we initiated a structure–activity relationship study that identified 2-aminobenzoxazole as a viable scaffold. …”

Data from: Meta-analysis shows that overabundant deer (Cervidae) populations consistently decrease average population abundance and species richness of forest birds by Robert Crystal-Ornelas (8486799)

Selected bones of <i>Sulf1</i>^−/−<i>Sulf2</i>^−/− embryos show decreased volume. by Charles R. Holst (30113)

Figure S7 from Circadian Oscillations Persist in Cervical and Esophageal Cancer Cells Displaying Decreased Expression of Tumor-Suppressing Circadian Clock Genes by Pauline J. van der Watt (15068109)

Table_1_Sown alfalfa pasture decreases grazing intensity while increasing soil carbon: Experimental observations and DNDC model predictions.docx by Lijun Xu (195394)

Table_2_Sown alfalfa pasture decreases grazing intensity while increasing soil carbon: Experimental observations and DNDC model predictions.xlsx by Lijun Xu (195394)

Removal of ascending depressor nerve abolished acute hypoxia-induced increases in RSNA, while enhanced the decrease in ABP in both control and HIH rats. by Fang Cui (313685)

Data Sheet 1_Quantum tunneling and barrier hopping in MgTi2O5 nanoparticles: a study of AC/DC conductivity and dielectric response.pdf by A. S. Salwa (22686665)

“…Additionally, dielectric investigation of MgTi₂O₅ NPs within the frequency range from (200 – 5 MHz) and the temperature range from (318K–433K) revealed that both real (ε₁) and imaginary (ε₂) components of a dielectric permittivity decrease as the frequency increased and increased as a temperature increased due to thermal motion of electrons, which is related to the polarization mechanism.…”

DataSheet_1_microRNA-155 Is Decreased During Atherosclerosis Regression and Is Increased in Urinary Extracellular Vesicles During Atherosclerosis Progression.docx by Stephen Fitzsimons (9856793)

“…Previous transcriptomic analysis led us to hypothesize that miR-155-5p (miR-155) is regulated by conjugated linoleic acid (CLA), a pro-resolving mediator which induces regression of atherosclerosis in vivo. …”