Plasma pharmacokinetics and brain uptake of 2B3-101 and pegylated liposomal doxorubicin in healthy mice. by Pieter J. Gaillard (506968)

“…<p>(A) Plasma concentration after 1 IV dose (5 mg/kg in 3 mice per group per time point) decreases with time for both liposomal formulations. …”

The concentration dependence of toxicogenomic responses and the synergistic effects of low doses by Lixin Yang (41431)

“…</p><p></p> Embryos were exposed to decreasing concentrations of Cd (a, lane 1, 5 mg/l: lane 2, 2.5 mg/l; lane 3, 0.5 mg/l), or MeHg (b, lane 1, 60 μg/l; lane 2, 30 μg/l; lane 3, 6 μg/l) or TCDD (c, lane 1, 500 ng/l; lane 2, 250 ng/l; lane 3, 50 ng/l). …”

Supplementary Material for: Changes in Cerebral Volume and White Matter Integrity in Adults on Hemodialysis and Relationship to Cognitive Function by Richerson W.T. (9512780)

“…<b><i>Conclusions:</i></b> HD patients have a pattern of decreased white matter integrity and gray matter atrophy compared to controls. …”

Supplementary Material for: Trends in One-Year Recurrent Ischemic Stroke among the Elderly in the USA: 1994–2002 by Allen N.B. (4121671)

“…After adjustment for changing patient demographics and comorbidities, there was a 4.5% decrease in recurrent stroke rates from 1994–1996 (13.2%) to 2000–2002 (12.6%; p for trend <0.0001). …”

microRNA-14 as an efficient suppressor to switch off ecdysone production after ecdysis in insects by Kang He (189002)

“…<p>The precise increase and decrease of hormone ecdysone are critical for accurate development in insects. …”

Conditional ablation of <i>Tra2b</i> causes perinatal lethality and disturbed cortical patterning in mice. by Markus Storbeck (191895)

“…Cells of the ventricular and subventricular zones of the cortex show strongest decrease in staining intensity (black arrowhead). Scale bar equals 400 µm; ctx, cortex; th, thalamus; cpt, caudoputamen; cp, cortical plate; iz, intermediate zone; svz, subventricular zone; vz, ventricular zone; sn, septal nuclei; 3v, third ventricle; lv, lateral ventricle; pc, choroid plexus.…”

Right Ventricular Dyssynchrony Before and After Pulmonary Thromboendarterectomy in Patients with Chronic Thromboembolic Pulmonary Hypertension by Darrin J. Wong (4230487)

“…</p> <p><b>Conclusions:</b> There was a significant decrease in the standard deviation of the mean peak systolic strain and time to peak strain (dyssynchrony) of the three RV free-wall segments after PTE. …”

Assessment of SnO2 nanoparticles' impact on local Pichoclorum atomus growth performance, cell morphology and metabolites content by Bounnit, Touria

“…The current study investigates the ecotoxicity of SnO2 nanoparticles on a local marine algae isolate. Five different concentrations (1, 5, 25, 50 and 100mg/L) were tested and the culture was followed for 72h. …”
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Table1_Sewage Sludge-Induced Effect on Growth, Enzyme Inhibition, and Genotoxicity can be Ameliorated Using Wheat Straw and Biochar in Pheretima posthuma Earthworms.docx by Hira Khalid (8844602)

“…Similarly, a maximum decrease in length was observed with sewage sludge (2.5%) followed by biochar (0.80%) at a 25% application rate. …”

Ligand Substitutional Effects on Molecular Dynamics and Broadband Near-White Emission in 2D 2‑Fluoroethylammonium Cadmium Chlorobromide by Maciej Ptak (1713061)

“…Optical studies showed that ligand substitution causes narrowing in bandgap energy from 5.12 to 4.28 eV and triggering of white to yellow-green emission thermally quenched above 240 K.…”

Human MADD fibroblast cells display similar mitochondrial defects as <i>xav</i> mutants. by Yuanquan Song (238595)

“…The expression of ROS related genes are also altered in Patient 1, with a ca. 20% decrease in <i>catalase</i> and 4.7 and 5.7 fold increase in <i>glutathione reductase</i> and <i>HSPA9</i> expression (N = 3–7 replicates of cells from passage 7–12; Student's t test, * p<0.05, ** p<0.01, *** p<0.001).…”

Supplementary Material for: Effect of SOM230 (Pasireotide) on Corticotropic Cells: Action in Dogs with Cushing’s Disease by Castillo V. (4126174)

“…SOM230 (pasireotide) is a multiligand somatostatin (SRIF) analog able to bind to somatostatin receptor (SSTR) subtypes 1, 2, 3 and 5, and trigger antisecretory and antiproliferative signaling cascades. …”

Ligand Substitutional Effects on Molecular Dynamics and Broadband Near-White Emission in 2D 2‑Fluoroethylammonium Cadmium Chlorobromide by Maciej Ptak (1713061)

“…Optical studies showed that ligand substitution causes narrowing in bandgap energy from 5.12 to 4.28 eV and triggering of white to yellow-green emission thermally quenched above 240 K.…”

Breast tumor cells expressing high or low levels of HA adhere differently to cells during low flow conditions. by Yan Du (229593)

“…<p>(A) The number of HS-578T and MCF-7 cells adhered to COS-7^LYVE-1(+) and COS-7^LYVE-1(−) cells under 0.1 dyn/cm² low shear stress was evaluated by counting 5 random views of fluorescence microscope images. …”

The −615 to −624 bp region of the ET_B receptor promoter is the AP-1 binding site in HNPE cells. by Shaoqing He (143800)

“…<p><b>A.</b> 0.5 µg of ET_B receptor promoter constructs and 0.5 µg of either the empty vector or c-Jun expressing plasmid DNA were co-transfected into HNPE cells in each well of a 12-well plate. …”

Table 1_Impact of donor transaminases on liver transplant utilisation and unnecessary organ discard: national registry cohort study.docx by Joseph J. Dobbins (19536196)

“…AST was also a significant predictor of liver decline. 18.5% of livers from DBD donors with ALT > 40 U/L (n = 1,683) were declined for transplantation. …”

TgRON2-2 inhibits <i>T. gondii</i> invasion by interfering with endogenous RON2-AMA1 interaction. by Mauld Lamarque (230588)

“…<p>(A) Extracellular tachyzoites were pre-incubated with either GST or TgRON2-2 at 125 µg/ml (3.75 µM) or 250 µg/ml (7.5 µM), before being added to confluent HFF monolayers for 30 min. …”

Supplementary Material for: Effect of Fludrocortisone on Intradialytic Hypotension: An Open-Label, Randomized, Crossover Study by Vongchaiudomchoke T. (14225873)

“…<b><i>Results:</i></b> A total of 17 patients were recruited with a mean age of 61.7 ± 14.8 years. …”

Outcomes of the two-layer model determined by the MCMC fitting to the pulse and prolonged protocols. by Laurent Mackay (4248592)

“…The bath medium had Na⁺ replaced by NMDG⁺ modeled by setting <i>E</i>₁ = −93.5 mV and <i>E</i>₂ = −5.1 mV. Voltage was ramped from − 80 mV to + 80 mV twice per second from a holding potential of − 60 mV. …”

Mitochondrial Complex IV Remodeling after miR-181c Treatment. by Samarjit Das (561679)

“…(D) Western blot shows the changes of other isoforms of mitochondrial respiratory chain complex IV. We have observed a significant decrease in the protein content of COX VIIa in the miR-181c overexpression groups, but no effect on COX 5A and COX 5B. α-tubulin was used as the loading control. …”