Modelling of the effects of En1 and En2 on hippocampal cells. by Asma Soltani (4356841)

“…In normal conditions (black lines), low levels of endogenous secreted En1 (from GABA cell for instance) could participate to dendritogenesis (1), spinogenesis (2) (insert), and mTOR signaling (3) in neighbor glutamatergic neurons. In a pathological context, such as autism (red lines), a rise of En2 expression and secretion would generate additional effects, i.e. the increase in dendritic complexity of GABA cells (4), a decrease of clustered PSD95 (5), and the mispairing of glutamatergic synapses (6) (insert). …”

cGMP-Dependent Protein Kinase Type I Is Implicated in the Regulation of the Timing and Quality of Sleep and Wakefulness by Sonja Langmesser (57421)

“…Moreover, PRKG1 deficiency results in an aberrant pattern, and consequently a reduced quality, of sleep and wakefulness, possibly due to a decreased wake-promoting output of the circadian system impinging upon sleep.…”

Altered Cerebrospinal Fluid Proteins in Smith–Lemli–Opitz Syndrome by Wenping Li (440398)

Olfactory Bulb Glomerular NMDA Receptors Mediate Olfactory Nerve Potentiation and Odor Preference Learning in the Neonate Rat by Rebecca Lethbridge (173780)

“…<em>Ex vivo</em> experiments using bulbs from trained rat pups reveal an increase in the AMPA/NMDA EPSC ratio post-training, consistent with an increase in AMPA receptor insertion and/or the decrease in NMDAR subunits. These results support a model of a cAMP/NMDA interaction in generating rat pup odor preference learning.…”

Creating an amplifier of weak selection for death-Birth updating. by Benjamin Allen (408337)

“…We solve for remeeting times according to Eqs <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007529#pcbi.1007529.e014" target="_blank">(5)</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007529#pcbi.1007529.e015" target="_blank">(6)</a>, and identify the vertex with the largest remeeting time (<i>τ</i>_<i>i</i> ≈ 18.29, shown in magenta). …”

Use of 2-Aminopurine Fluorescence To Examine Conformational Changes during Nucleotide Incorporation by DNA Polymerase I (Klenow Fragment)^† by Vandana Purohit (2947848)

“…Finally, when the primer had a 3‘-OH, a fluorescence decrease with a rate equal to the rate of nucleotide incorporation was observed with both 0 and +1 position reporters. …”

Association between Regulator of G Protein Signaling 9–2 and Body Weight by Jeffrey L. Waugh (194865)

“…We identified a naturally occurring 5 nucleotide deletion polymorphism in the human <em>RGS9</em> gene and found that the mean body mass index (BMI) of individuals with the deletion was significantly higher than those without. …”

An immunohistochemically stained photomicrograph of the stomach mucosa using an anti-TLR4 antibody. by Rehab F. Taher (20478600)

“…<p>(a) few TLR4-positively stained cells in the normal group; (b) the control ethanol group showed elevated TLR4 expression and a higher proportion of positive cells having deep brown coloring, (c) Omeprazole group showed reduction in the percentage of TLR4 positive cells with strong brown coloring, (d) PM-EtOH (25 mg/kg) group showed lowered percentage of TLR4 positive cells with weak cytoplasmic staining, (e) PM-EtOH (5o mg/kg) group showed decreased percentage of TLR4 positive cells, (f) PM-EtOH (100 mg/kg) group giving weak TLR4 expression, with a significant decrease in TLR4-positively stained cells(TLR4 immunohistochemical staining; Scale bar=100µm).…”

An Inducible Cell-Cell Fusion System with Integrated Ability to Measure the Efficiency and Specificity of HIV-1 Entry Inhibitors by Alon Herschhorn (198447)

“…Target cells express the HIV-1 receptors, CD4 and CCR5, and carry the firefly luciferase (F-Luc) reporter gene under the control of a tTA-responsive promoter. …”

Circular Dichroism analysis, PPIase activity and nickel regulation of <i>H</i>. <i>pylori</i> WT and mutant SlyD proteins. by Milica Denic (9987685)

“…<p><b>A.</b> Circular Dichroism spectra of SlyD wild type and mutant proteins were analyzed in 5 mM phosphate buffer (pH = 7.6). …”

Altered Cerebrospinal Fluid Proteins in Smith–Lemli–Opitz Syndrome by Wenping Li (440398)

Performance and economic viability of tambaqui, Colossoma macropomum, selectively bred for weight gain by Ana Carla Carvalho SILVA (10374162)

“…The total production cost estimations indicated that fish from family B would allow for a 4% reduction in the average fixed cost and a 1% decrease in the total average production cost.…”

Representative kinetic traces illustrating the JRA-associated abnormality in metabolic oscillations of neutrophils by James N Jarvis (3342)

“…However, in contrast to MPO-negative cells, MPO-positive cells undergo both a decrease in period to 10 seconds and a dramatic increase in the oscillatory amplitude. …”

Changes in Expression Levels of miR-1 and miR-133 and their targets in canine HF Myocytes. by Andriy E. Belevych (338034)

“…*p<0.05, n = 5. C. Representative Western blots of putative targets of miR-1 and -133, regulatory subunits B56α, B56δ and catalytic subunit of PP2A respectively. …”

Lab 3: Biol2050 Abundance and Diversity in Insects Data Set 1 by Katrin Chapkis (797943)

“…When the wind speed was found in the Beaufort scale, it was given a Beaufort number of 5, which corresponded to Fresh Breeze in Seaman's term.…”

Chronic intermittent exposure to ayahuasca during aging does not affect memory in mice by N.F. Correa-Netto (6510125)

“…Twenty-eight male c57bl/6 mice (6 months old) received ayahuasca or water (1.5 mL/kg, orally) twice a week for 12 months and were tested in the Morris water maze (MWM), open field and elevated plus maze (EPM) tasks before and after treatment. …”

Data_Sheet_1_Timing Training in Female Soccer Players: Effects on Skilled Movement Performance and Brain Responses.pdf by Marius Sommer (5581820)

“…Accordingly, this study investigated the effects of timing training on soccer skill performance and the associated changes in functional brain response in elite- and sub-elite female soccer players. Twenty-five players (mean age 19.5 years; active in the highest or second highest divisions in Sweden), were randomly assigned to either an experimental- or a control group. …”

Use of 2-Aminopurine Fluorescence To Examine Conformational Changes during Nucleotide Incorporation by DNA Polymerase I (Klenow Fragment)^† by Vandana Purohit (2947848)

“…Finally, when the primer had a 3‘-OH, a fluorescence decrease with a rate equal to the rate of nucleotide incorporation was observed with both 0 and +1 position reporters. …”

Use of 2-Aminopurine Fluorescence To Examine Conformational Changes during Nucleotide Incorporation by DNA Polymerase I (Klenow Fragment)^† by Vandana Purohit (2947848)

“…Finally, when the primer had a 3‘-OH, a fluorescence decrease with a rate equal to the rate of nucleotide incorporation was observed with both 0 and +1 position reporters. …”

Stimulation-induced changes in STN power. by Damian M. Herz (16007088)

“…Stimulation led to an approximately 40% decrease in beta power, which returned to baseline after approximately 0.5 s (mean burst duration was 250 ms +/− 100 drawn from a uniform distribution). …”