Effects of anesthesia on zebrafish locomotion (n = 28). by Yali Ge (417371)

Subjects:

Comparison in baseline variables between efficacy group and non-efficacy group. by Naruyoshi Gyoutoku (22537831)

Subjects:

Comparison of ALT (A), AST (B), and Fib-4 index (C) before and after imeglimin treatment in ALT ≥ 25 IU/L and ALT < 25IU/L groups. by Naruyoshi Gyoutoku (22537831)

Subjects:

Morphology of zebrafish and deformities induced by propofol in each period. by Yali Ge (417371)

Subjects:

Clinical characteristics at baseline and at the end of the study. by Naruyoshi Gyoutoku (22537831)

Subjects:

Modeling of the BXA-rPA_N binding interface of A(H1N1)pdm09 with E23G/K. by Jeremy C. Jones (9248188)

<i>Gbx1^−/−</i> embryos display abnormal projection of proprioceptive afferents and decrease in peripherin+ ventral motor neurons. by Desirè M. Buckley (5651401)

“…<i>Gbx1^−/−</i> embryos also show a marked decrease in the expression of peripherin+ ventral motor neurons (brackets) in (B and D) when compared to control mice (A and C). …”

Leishmanization with <i>L</i>. <i>major</i> + Pam3CSK4 decreases lesion size and parasite burden in mice. by Lu Huang (211625)

Longitudinal phenotypic study of late-onset retinal degeneration due to a founder variant c.562C>A p.(Pro188Thr) in the <i>C1QTNF5</i> gene by Julie De Zaeytijd (3633118)

“…</p> <p><b>Results</b>: Best-corrected visual acuity (BCVA) and visual fields were maintained up to 50 to 55 years (n = 8), with a gradual decline, but conservation of functional central vision between 55 to 65 years (n = 15), followed by a steep decrease in overall visual function beyond 65 years (n = 9). …”

Most miRNAs in Ago1 RISC are stable with age whereas transposon siRNAs in Ago2 RISC decrease with age. by Siobhan Gartland (14129274)

“…(A) miRNAs in Ago1 RISC from old and young males are plotted as percentage of mapped reads. miR-34-5p increases with age by more than 2-fold while miR-14-3p does not. …”

Infection with <i>Shigella flexneri</i> M90T<i>ΔaroA</i> results in a decrease in TAMs number. by Katharina Galmbacher (252251)

Data_Sheet_1_Non-canonical Interaction Between O-Linked N-Acetylglucosamine Transferase and miR-146a-5p Aggravates High Glucose-Induced Endothelial Inflammation.PDF by Wan-Yu Lo (444892)

“…Real time PCR analysis found that miR-146a-5p was decreased in HG- and glucosamine-stimulated HAECs. …”

Sodium butyrate alleviates potential Alzheimer’s disease in vitro by suppressing Aβ and tau activation and ameliorates Aβ-induced toxicity by Al Borhan Bayazid (16711360)

“…We have investigated the neuroprotective effects of NaB in SH-SY5Y cells stimulated with TNF-α/Aβ in SH-SY5Y cells and LPS-induced BV-2 cells. …”

Numbers of new neurons in Area X as a function of hemisphere and experimental condition. by Jake V. Aronowitz (11361921)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…In this study, we report the first highly selective HDAC6 inhibitor with hydrazide as the zinc-binding group (ZBG), which displays superior pharmacokinetic properties to the current hydroxamic acid inhibitors. …”

Discovery of Triazolyl Derivatives of Cucurbitacin B Targeting IGF2BP1 against Non-Small Cell Lung Cancer by Fan-Fan Shang (16953264)

“…Cucurbitacin B (CuB) is a potent but toxic anticancer natural product. Herein, we designed and synthesized 2-OH- and 16-OH-modified CuB derivatives to improve their antitumor efficacy and reduce toxicity. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…In this study, we report the first highly selective HDAC6 inhibitor with hydrazide as the zinc-binding group (ZBG), which displays superior pharmacokinetic properties to the current hydroxamic acid inhibitors. …”

Presentation_1.PDF by Suborno Jati (5073956)

“…We found that during the initial hours of infection with PA and SP, there is decrease in the steady state levels of the Wnt5A protein in macrophages. …”

Deseasonalized anomaly time series of temperature ((a), (b)) and precipitation minus evaporation (<em>P</em> − <em>E</em>) changes over the tropical oceans and the tropical land fo... by Chunlei Liu (57542)

“…The wet and dry regions are defined as the 30% highest and 70% lowest <em>P</em> − <em>E</em> grid points each month. Data are from the CMIP5 historical and RCP 4.5 simulations (1850–2100) and the AMIP simulations (1979–2008). …”

Figure 2 The serotonin biosynthetic enzyme TPH-1 is required in chemosensory neurons to inhibit the Dar phenotype and decrease pathogen clearance rates by Rachel Mcmullan (506214)