Autophagic blockage by metformin-loaded PLGA nanoparticles causes cell cycle arrest of HepG2 cells - supplementary figure by Chen Chen (6544)

Microtomographic, histomorphometric, and molecular features show a normal alveolar bone healing process in iNOS-deficient mice along a compensatory upregulation of eNOS and nNOS is... by Carolina Fávaro FRANCISCONI (14820181)

Effect of DOX and DMNQ on mRNA translation in the heart <i>in vivo</i> after an acute dose with time. by Amy V. Pointon (241923)

“…All genes that were significantly altered (P≤0.05) in expression in at least one time point were included. Magenta is increased expression and blue decreased expression the densest colour representing a 2.5 log fold change (5.6 fold) from time matched control. …”

Effect of DOX and DMNQ on gene transcription in the heart <i>in vivo</i> after an acute dose over time. by Amy V. Pointon (241923)

“…Genes significantly altered (p≤0.05) in expression in at least one time point were included. Magenta is increased expression and blue decreased expression with the densest colour representing a 2.5 log fold (5.6 fold) change from time matched control. …”

Replication data for: Hazel dormouse in managed woodland select for young, dense, and species-rich tree stands by Rasmus Mohr Mortensen (9512723)

“…We modelled selection at home range level as the conditional probability of occupancy of 588 nest boxes and nest tubes in 15 managed forests relative to habitat variables measured within 25 m radius. …”

Table_1_Research on the effects of rs1800566 C/T polymorphism of NAD(P)H quinone oxidoreductase 1 gene on cancer risk involves analysis of 43,736 cancer cases and 56,173 controls.d... by Hangsheng Zhou (7305830)

Image_1_Research on the effects of rs1800566 C/T polymorphism of NAD(P)H quinone oxidoreductase 1 gene on cancer risk involves analysis of 43,736 cancer cases and 56,173 controls.t... by Hangsheng Zhou (7305830)

KCNQ Channels Show Conserved Ethanol Block and Function in Ethanol Behaviour by Sonia Cavaliere (116850)

“…We show that the single KCNQ channel in <em>Drosophila</em> (dKCNQ) has similar electrophysiological properties to neuronal KCNQ2/3, including conserved acute sensitivity to ethanol block, with the fly channel (IC₅₀ = 19.8 mM) being more sensitive than its mammalian ortholog (IC₅₀ = 42.1 mM). …”

Image_1_Effect of Physical Training on Exercise-Induced Inflammation and Performance in Mice.TIFF by Luiz Alexandre Medrado de Barcellos (10095388)

BC CLC-Pred: a freely available web-application for quantitative and qualitative predictions of substance cytotoxicity in relation to human breast cancer cell lines by A.A. Lagunin (810465)

“…The separate datasets related with IC₅₀ and IG₅₀ values were used for the creation of (Q)SAR models for each cell line. …”

Effects of metformin on angiogenic activities and apoptosis of hRVECs. by Jing Han (43038)

“…After exposure to metformin at 0–50 mM for 6 hours, total length of capillary-like network formed by hRVECs decreased significantly and dose-dependently. …”

Increases of oxidative stress induce reduction of ΔΨ_m in <i>DJ-1</i>+/+ MEFs. by Emilie Giaime (316501)

“…All data are expressed as mean ± SEM. *<i>p</i><0.05, **<i>p</i><0.01, ***<i>p</i><0.001.…”

9.2.27PE in combination with ABT-737 induces apoptosis in melanoma cells. by Karianne Risberg (207221)

“…To determine whether caspases and cathepsins were involved in the decreased cell viability caused by the combination of 9.2.27PE and ABT-737, the cells were pre-treated with for 1 h with Z-VAD-FMK (50 µM)±Z-FA-FMK (50 µM). …”

CPZ pretreatment inhibits cleaved caspase-3 expression in rat brains after ethanol exposure. by Jing Wu (54032)

“…<p>(A) The diagram shows the cross section of the cerebrum, and the regions of the parietal cortex and CA1 of hippocampus are pointed out. (B) Cleaved caspase-3 labeling corresponds to brown staining could be observed in the cytoplasm and nuclei. …”

Accelerated recovery from mechanical and thermal hyperalgesia following nerve injury in EphB1 KO mice. by Vincent Cibert-Goton (288406)

“…This reduction in paw withdrawal latency was significantly smaller in EphB1 KO mice at all time points, except 5 days after injury. WT mice also developed mechanical allodynia with a marked decrease in stimulus intensity required to trigger a lifting response of the injured paw as compared to baseline. …”

Figure S3 The Dar phenotype increases pathogen clearance rates but is not reversed by pathogen clearance by Rachel Mcmullan (506214)

“…The rate of clearance of SYTO13 labeled bacteria from the C. elegans rectal opening was measured. 5-HT treated Dar animals cleared the pathogen at a similar rate to wild type, untreated, control animals however the rate of pathogen clearance was significantly decreased in 5-HT treated Dar-defective animals.…”

Effect of Sonication Time on Degree of Chromatin Shearing in Fresh or Frozen Cell Suspensions. by Pamela D. Schoppee Bortz (199468)

“…<p>Fixed rat SMC (10⁷ cells/ml) were sonicated in 5 min intervals from 5 to 30 min then reverse cross-linking was performed before DNA was extracted using PCIA. …”

Hyperthermia-Induced Disruption of Functional Connectivity in the Human Brain Network by Gang Sun (80623)

“…</p> <p>Methodology and Principal Findings</p><p>We simulated 1 hour environmental heat exposure to thirty-six participants under two environmental temperature conditions (25°C and 50°C), and collected resting-state functional brain activity. …”

<i>In vitro</i> viability results after CAG treatment. by Lina A. Al-Ani (6697301)

“…<p>Percentage viability of colon cancer cells (HT-29 and SW948 cell lines), normal colon cells (CCD841), and normal liver cells (WRL-68), upon exposure to CAG nanocomposite at different concentrations (62.5–1000 μg/mL), measured at three time points using WST-8 assay. …”

Partial dependence plots obtained with Boosted Regression Trees using four predictors (depth, distance from 100 m isobath, distance offshore and exposure). by Zaira Matheus (6195113)