Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity by Imran Ramzan (15430807)

“…The BCAA-restricted diet marginally lowered Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) levels: baseline 1.5 ± 0.2 to 1.0 ± 0.1; (p = 0.096).</p> <p>Conclusion: We successfully lowered circulating BCAAs by 50% while maintaining iso-nitrogenous, iso-caloric dietary intakes, and while meeting the recommended daily allowances (RDA) for protein requirements. …”

Associations between initial neutralizing antibody potency and rate of declining neutralization potency over time. by Lindsay Wieczorek (171734)

“…<p>For each neutralizing antibody (NAb), the geometric mean (GM) IC₅₀ was determined for all PSVs from an earlier and later decade period, as shown in the x-axis title. …”

Bortezomib-induced NF-κB activation. by Li Jia (76051)

“…<p>Su-DHL8 cells were treated with 20 nM bortezomib with or without 50 µg/ml of CQ. (A and B) Effects of bortezomib or/and CQ on the levels of NF-κB proteins. …”

Expression of the miR-34 family, Axl and HNF4A in RCC. by Helena K. Fritz (785130)

“…(<b>C</b>) Kaplan-Meier survival analysis for miR-34a in ccRCC patients, divided into two groups; the 50% of patients with miR-34a expression above median versus the 50% of patients with miR-34a expression below median. …”

Effects of polydatin on hepatic biochemical parameters in CCl₄-injured mice. by Hong Zhang (25820)

“…<p>Intraperitoneal injection of CCl₄ (50 µl/kg) obviously decreased the hepatic activities of SOD, GSH, GST, GPx and CAT, and increased hepatic MDA concentration in mice. …”

Relative frequencies of gene triplets. by Théotime Grohens (22331974)

Hysteresis-loop bursting in the DTB bursting model. by Maria Luisa Saggio (3045213)

“…Saddle-Node (SN) and supercritical Hopf (SupH) curves meet at the Takens-Bogdanov point TB. Bifurcation curves partition the map in five regions with different state space configurations (Roman Numerals). …”

I_NaP evoked by ramps with different slopes. by Elisa Colombo (286321)

“…The graph in C displays the mean values of the I_NaP peaks measured on five neurons in response to 100, 50 and 10 mVs⁻¹ ramps under control conditions, in the presence of PHT and after PHT wash out.…”

Protein level affects epitope detection. by Phyllis S. Frisa (370425)

“…Cyclin B1 intensity was maximal at 25–50 µg trypsin inhibitor and decreased at lower and higher protein levels. …”

Lysosomes accumulated in <i>jip3^nl7</i> axon terminal swellings. by Catherine M. Drerup (383296)

“…(H) Retrograde, but not anterograde, lysosome transport frequency was decreased in <i>jip3^nl7</i> mutants at 3 and 5 dpf (Wilcoxon rank-sum; **-<i>p</i><0.005). …”

The effects of PRP, PPP, HGF and HGF antibody on PGE₂ production in wounded mouse Achilles tendons <i>in vivo</i>. by Jianying Zhang (256508)

“…However, PPP treatment did not significantly decrease PGE₂ levels in the tendon tissues at all time points post-treatment (P>0.05). …”

Data_Sheet_1_Preoperative Creatinine Clearance and Mortality of Elective Cardiac Surgery in Hospitalization: A Secondary Analysis.docx by Lu Chen (75170)

“…</p>Conclusion<p>In the range of 8.9–78.5 (Cockcroft), an increase in preoperative creatinine clearance is associated with a decrease in postoperative mortality with patients younger than 80 years old. …”

Analysis of LRRK2 effect on DRD2 total protein level. by Mauro Rassu (4068670)

“…***p<0,001 Two-way ANOVA and Bonferroni post test were used. <b>(E)</b> SH-SY5Y-DRD2 transduced as in (A) were treated for different time points (15', 30', 45', 60') by puromycin, then cell lysates were prepared and analyzed by western blot. …”

Image 4_Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials... by Virginie Piffaut (22399978)

“…</p>Results<p>While ascorbic acid did not exhibit any efficacy versus its vehicle in limiting skin hyperpigmentation induced by HEV, the use of 2-MNG (0.5 or 1%) led to an early significant decrease in HEV-induced pigmentation, which was sustained until the end of the study, as evidenced by colorimetry and significantly scored by visual assessment. …”

Image 3_Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials... by Virginie Piffaut (22399978)

“…</p>Results<p>While ascorbic acid did not exhibit any efficacy versus its vehicle in limiting skin hyperpigmentation induced by HEV, the use of 2-MNG (0.5 or 1%) led to an early significant decrease in HEV-induced pigmentation, which was sustained until the end of the study, as evidenced by colorimetry and significantly scored by visual assessment. …”

Image 1_Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials... by Virginie Piffaut (22399978)

“…</p>Results<p>While ascorbic acid did not exhibit any efficacy versus its vehicle in limiting skin hyperpigmentation induced by HEV, the use of 2-MNG (0.5 or 1%) led to an early significant decrease in HEV-induced pigmentation, which was sustained until the end of the study, as evidenced by colorimetry and significantly scored by visual assessment. …”

Image 2_Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials... by Virginie Piffaut (22399978)

“…</p>Results<p>While ascorbic acid did not exhibit any efficacy versus its vehicle in limiting skin hyperpigmentation induced by HEV, the use of 2-MNG (0.5 or 1%) led to an early significant decrease in HEV-induced pigmentation, which was sustained until the end of the study, as evidenced by colorimetry and significantly scored by visual assessment. …”

Linagliptin ameliorates albuminuria and kidney hypertrophy in DBA/2J diabetic mice but not in G6PD^- mice at 12 weeks. by Netanya Y. Spencer (5488931)

Image_1_Both Natural and Induced Anti-Sda Antibodies Play Important Roles in GTKO Pig-to-Rhesus Monkey Xenotransplantation.tif by Hao Feng (54208)

“…Both the overall binding of monkey serum IgM/IgG antibody to GTKO pig PBMCs and CDC against these PBMCs decreased significantly with a progressive reduction in Sda expression, showing a clear dose-effect relationship. …”

Supplementary Material for: Remote Ischemic Preconditioning Reduces the Risk of Contrast-Induced Nephropathy in Patients with Moderate Renal Impairment Undergoing Percutaneous Coro... by Deng J. (4043975)

“…The application of RIPC decreased the incidence of CIN (relative risk, RR, 0.50, 95% confidence interval, CI, 0.39–0.65; <i>p</i> < 0.001). …”