Celastrol has an inhibitory effect on TNFα-induced NF-κB signaling in MDA-MB-231 cells. by Laura Mezzanotte (223692)

“…<p>(3.A) Graph representing the decrease in fold NF-κB induction in MDA-MB-231 cells using celastrol by the multicolor assay (* p value <0.05; ** p value <0.01). (3.B) Composite image of the unmixed spectrum of luciferases: green signals represent CBG99 emission, red signals represent PpyRE9 emission spectrum and blue signals represent ExtGluc expression in control cells (first column) and cells treated with TNFα in combination with increasing concentrations of celastrol (0.1–3 µM). (3.C) Left: graph reporting the relative band intensity of p65 protein from the nuclear extract of control sample and samples treated with TNFα (10 ng/ml) or TNFα + celastrol (0.1 µM; 0.5 µM and 1 µM). …”

Data_Sheet_1_Ecogenomics-Based Mass Balance Model Reveals the Effects of Fermentation Conditions on Microbial Activity.pdf by Jinha Kim (7540949)

“…The growth rates of syntrophs and fermenters, such as Syntrophomonas and Parabacteroides increased with a decrease in SRT. In contrast, treatment conditions, such as inoculum heat shock and high incubation temperature inhibited the growth of WAS-associated populations, such as Terrimonas and Bryobacter. …”

Changes of cytokine production and of C Reactive Protein with the clinical course of HS. by Theodora Kanni (368357)

“…PBMCs were stimulated with LPS of <i>Escherichia coli</i> O55:B5; with heat-killed <i>Candida albicans</i> (HKCA); and with heat-<i>Staphylococcus aureus</i> (HKSA) for the production of (A) tumour necrosis factor-alpha (TNFα), (B) interleukin (IL)-1β, (C) IL-17 and (D) C Reactive Protein (CRP). …”

Change in Replication Capacity (RC) during 4 months of structured treatment interruption (STI). by Agnes C. Paquet (231161)

“…<p>Panel A: Distribution of Replication Capacity of the patient virus at baseline (BL), 2 months and 4 months of STI. …”

Wld^S delays paraquat-induced mitochondrial damage in MEFs. by Qiujing Yu (215044)

“…<p>(A) Wld^S attenuated paraquat-induced disruption of mitochondrial membrane potential. …”

EVALUATION OF THE ANTIBACTERIAL ACTIVITY OF Crotalus durissus terrificus CRUDE VENOM by Jefferson do Carmo Dietz (5960732)

“…<div><p>Abstract Snake venoms are recognized as a promising source of pharmacologically active substances and are potentially useful for the development of new antimicrobial drugs. …”

Influence of elevated temperature on bovine oviduct epithelial cells (BOECs) by Łukasz Rąpała (5400590)

“…The elevated temperature had no effect on the viability of BOECs but exerted a negative effect on embryo development. The elevated temperature increased the expression of HSP70 and decreased the expression of OVGP1 at both mRNA and protein levels in BOECs cultured alone and those co-cultured with embryos. …”

Natural Rubber-Based Elastomer Reinforced by Chemically Modified Multiscale Leather Collagen Fibers with Excellent Toughness by Shuangyang Li (2421853)

“…Unfortunately, an increase in tensile strength for NR is always accompanied by a decrease in extensibility. In this paper, an NR-based composite elastomer reinforced by triethoxyvinylsilane-modified leather collagen fibers (M-LCF) was fabricated for the first time to improve the tensile strength and the extensibility of the rubber composite simultaneously. …”

Wnt/β-catenin signaling down-regulation is both dependent and independent of HIF expression. by Donald J. Scholten II (649432)

“…Hypoxia (72 hour, 0.5% O₂) resulted in decreased axin2 mRNA expression relative to normoxia. …”

Natural Rubber-Based Elastomer Reinforced by Chemically Modified Multiscale Leather Collagen Fibers with Excellent Toughness by Shuangyang Li (2421853)

“…Unfortunately, an increase in tensile strength for NR is always accompanied by a decrease in extensibility. In this paper, an NR-based composite elastomer reinforced by triethoxyvinylsilane-modified leather collagen fibers (M-LCF) was fabricated for the first time to improve the tensile strength and the extensibility of the rubber composite simultaneously. …”

Effects of RhoB in invasion and migration of 786-O cells. by Weihao Chen (431221)

“…<p>The invasion (<b>A</b>) and migration (<b>B</b>) of 786-O cells transfected with pcDNA3.0-Flag-RhoB decreased nearly 4.59-fold (for invasion) and 5-fold (for migration) after transfection with pc-DNA3.0-Flag-RhoB compared with the empty vector. …”

Biological soil loosening by grasses from genus Brachiaria in crop-livestock integration by José Flávio Neto (12808759)

“…<div><p>Soil compaction associated with pastures degradation can decrease animal productivity, forage longevity and compromise environmental sustainability. …”

TGF-β₁ dependent effects on AP activity by SB431542 are depending on time. by Sabrina Ehnert (359631)

“…<p>Primary human osteoblasts stimulated with 5 ng/ml hra TGF-β₁ in the presence or absence of 20 nM SB431542. …”

PF-5177624 blocked IGF-I induced cell cycle progression in MCF7 and T47D cells. by Sangita M. Baxi (123560)

“…Bar graphs indicating the percentages of cells in the various cell cycle stages at the 72 hour time point are shown in (<b>A</b>) and (<b>B</b>)<b>.</b> Phosphorylation of Histone H3 was determined on cells treated with 5 µM PF5177624 for 24, 48, and 72 hours and normalized to DMSO treatment at the same time points as shown in (<b>C</b>). …”

EFFECTS OF PHYSICAL TRAINING ON THE MYOCARDIUM OF FEMALE LDL KNOCKOUT OVARIECTOMIZED MICE by Ledimar Brianezi (4695028)

“…The training caused the decrease in the density of the interstitial volume, and the hypercholesterolemia changed to a smaller one than the control group. …”

Changes in RNA expression and protein levels with ED-deleted MARCKS. by Timothy D. Rohrbach (680245)

“…<p><b>A)</b> After overnight doxycycline-induction of ΔED-MARCKS or WT-MARCKS U87 cells, RNA was collected and ran on NanoString nCounter GX Human Cancer Reference Kit. …”

Table_1_Hesperidin alleviates zinc-induced nephrotoxicity via the gut-kidney axis in swine.docx by Qingwen Yang (119119)

“…</p>Results<p>The results showed that hesperidin could effectively attenuate the pathological injury in kidney, and reduce autophagy and apoptosis induced by Zn, which evidenced by the downregulation of LC3, ATG5, Bak1, Bax, Caspase-3 and upregulation of p62 and Bcl2. …”

Scanning electron microscopy (SEM) photographs. by Igor Santos Fonte Bôa (838040)

“…The first column (A-F, scale bar = 10 μm) shows scanning images of whole glomeruli, showing structural preservation of the surface tissues in the NAC (C) and V 300 (F) groups, similar to the Control group. …”

Calorie Restriction Increases Muscle Mitochondrial Biogenesis in Healthy Humans by Anthony E Civitarese (69038)

“…</p> <h3>Conclusions</h3><p>The observed increase in muscle mitochondrial DNA in association with a decrease in whole body oxygen consumption and DNA damage suggests that caloric restriction improves mitochondrial function in young non-obese adults.…”

Table_1_Development of bacteria-based bioorganic phosphate fertilizer enriched with rock phosphate for sustainable wheat production.DOCX by Zoya Aslam (19196917)

“…For this purpose, potential heat-tolerant phosphate-solubilizing bacteria (PSB) were isolated from major wheat-growing areas of southern Punjab. Five isolates were the efficient phosphate solubilizers based on in vitro phosphate-solubilizing activity (291–454 μg ml⁻¹ and 278–421 μg ml⁻¹) with a concomitant decrease in pH (up to 4.5) at 45°C and 50°C, respectively. …”