Association analysis, given linkage, conditional on the top SNP. by Rohina Rubicz (104167)

“…The regression coefficients refer to the estimated change in the phenotype for each dose of the rarer SNP allele.</p>a<p>Since we used a liability threshold model for analysis of the dichotomous trait (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003147#s4" target="_blank">methods</a> section), the direction of effect on EBNA-1 discrete serostatus is opposite of the sign of the regression coefficient, but is in the same direction as the regression coefficient for the quantitative trait (e.g. for SNP rs204999, the minor allele is associated with a decrease in EBNA-1 antibody level and seronegativity).…”

The SMART Randomised Controlled Trial by Henrietta Graham (17017581)

“…A small change approach may therefore be an appropriate strategy to reduce the 0.5 to 1 kg of average adult weight gain seen each year and may lead to decreased prevalence of overweight and obesity over time. …”

Hierarchical transformation between consecutive network layers enhances word recognition performance and robustness of the optimal HSNN. by Fatemeh Khatami (4446235)

“…<p>(<b>a</b>) The average word accuracy at 5 dB SNR systematically increases across network layers for the optimal HSNN (<b>a</b>, blue) whereas the high-resolution HSNN exhibits a systematic reduction in word recognition accuracy (<b>a</b>, red). …”

Data from: Habitat loss predicts the functional extinction of fish from Amazonian streams during the Anthropocene by Lucas Colares (11379678)

“…The simulated extinction of vulnerable species led to a decrease in both the mean body size of the community and functional rarity, and culminated in abrupt losses of ecosystem function after 5% and 10% of extinction at local and regional scales. …”

Supplementary Material for: Time- and Stimulus-Dependent Characteristics of Innate Immune Cells in Organ-Cultured Human Corneal Tissue by Zhuang X. (5174906)

Table1_Sewage Sludge-Induced Effect on Growth, Enzyme Inhibition, and Genotoxicity can be Ameliorated Using Wheat Straw and Biochar in Pheretima posthuma Earthworms.docx by Hira Khalid (8844602)

“…Similarly, a maximum decrease in length was observed with sewage sludge (2.5%) followed by biochar (0.80%) at a 25% application rate. …”

Ligand Substitutional Effects on Molecular Dynamics and Broadband Near-White Emission in 2D 2‑Fluoroethylammonium Cadmium Chlorobromide by Maciej Ptak (1713061)

“…Optical studies showed that ligand substitution causes narrowing in bandgap energy from 5.12 to 4.28 eV and triggering of white to yellow-green emission thermally quenched above 240 K.…”

Human MADD fibroblast cells display similar mitochondrial defects as <i>xav</i> mutants. by Yuanquan Song (238595)

“…The expression of ROS related genes are also altered in Patient 1, with a ca. 20% decrease in <i>catalase</i> and 4.7 and 5.7 fold increase in <i>glutathione reductase</i> and <i>HSPA9</i> expression (N = 3–7 replicates of cells from passage 7–12; Student's t test, * p<0.05, ** p<0.01, *** p<0.001).…”

Supplementary Material for: Effect of SOM230 (Pasireotide) on Corticotropic Cells: Action in Dogs with Cushing’s Disease by Castillo V. (4126174)

“…SOM230 (pasireotide) is a multiligand somatostatin (SRIF) analog able to bind to somatostatin receptor (SSTR) subtypes 1, 2, 3 and 5, and trigger antisecretory and antiproliferative signaling cascades. …”

Ligand Substitutional Effects on Molecular Dynamics and Broadband Near-White Emission in 2D 2‑Fluoroethylammonium Cadmium Chlorobromide by Maciej Ptak (1713061)

“…Optical studies showed that ligand substitution causes narrowing in bandgap energy from 5.12 to 4.28 eV and triggering of white to yellow-green emission thermally quenched above 240 K.…”

Breast tumor cells expressing high or low levels of HA adhere differently to cells during low flow conditions. by Yan Du (229593)

“…<p>(A) The number of HS-578T and MCF-7 cells adhered to COS-7^LYVE-1(+) and COS-7^LYVE-1(−) cells under 0.1 dyn/cm² low shear stress was evaluated by counting 5 random views of fluorescence microscope images. …”

The −615 to −624 bp region of the ET_B receptor promoter is the AP-1 binding site in HNPE cells. by Shaoqing He (143800)

“…<p><b>A.</b> 0.5 µg of ET_B receptor promoter constructs and 0.5 µg of either the empty vector or c-Jun expressing plasmid DNA were co-transfected into HNPE cells in each well of a 12-well plate. …”

Table 1_Impact of donor transaminases on liver transplant utilisation and unnecessary organ discard: national registry cohort study.docx by Joseph J. Dobbins (19536196)

“…AST was also a significant predictor of liver decline. 18.5% of livers from DBD donors with ALT > 40 U/L (n = 1,683) were declined for transplantation. …”

TgRON2-2 inhibits <i>T. gondii</i> invasion by interfering with endogenous RON2-AMA1 interaction. by Mauld Lamarque (230588)

“…<p>(A) Extracellular tachyzoites were pre-incubated with either GST or TgRON2-2 at 125 µg/ml (3.75 µM) or 250 µg/ml (7.5 µM), before being added to confluent HFF monolayers for 30 min. …”

Supplementary Material for: Effect of Fludrocortisone on Intradialytic Hypotension: An Open-Label, Randomized, Crossover Study by Vongchaiudomchoke T. (14225873)

“…<b><i>Results:</i></b> A total of 17 patients were recruited with a mean age of 61.7 ± 14.8 years. …”

Outcomes of the two-layer model determined by the MCMC fitting to the pulse and prolonged protocols. by Laurent Mackay (4248592)

“…The bath medium had Na⁺ replaced by NMDG⁺ modeled by setting <i>E</i>₁ = −93.5 mV and <i>E</i>₂ = −5.1 mV. Voltage was ramped from − 80 mV to + 80 mV twice per second from a holding potential of − 60 mV. …”

Mitochondrial Complex IV Remodeling after miR-181c Treatment. by Samarjit Das (561679)

“…(D) Western blot shows the changes of other isoforms of mitochondrial respiratory chain complex IV. We have observed a significant decrease in the protein content of COX VIIa in the miR-181c overexpression groups, but no effect on COX 5A and COX 5B. α-tubulin was used as the loading control. …”

The effects of different modes of neurogenesis on OB structure and function. by David E. Chen Kersen (11547607)

“…The guided addition mode (green) had the strongest effect, leading to an average relative reduction of 23.4% (SEM = 0.0078, bottom panel), with 94.9% of all odor pairs having a net decrease in correlation (SEM = 0.0130). Meanwhile, the control mode (gray) produced little change in the relative reduction (mean = 2.5%, SEM = 0.0180), with 45.4% of odor pairs experiencing net decorrelation (SEM = 0.0548), about what one would expect from chance. …”

Table_1_Prevalence and WGS-based characteristics of MRSA isolates in hospitals in Shanghai, China.XLS by Hongzhi Zhang (425117)

“…<p>Methicillin-resistant Staphylococcus aureus (MRSA) isolates remain a serious threat to global health despite a decrease in MRSA infections since 2005. …”

The influence of health policy on early diagnosis and surgical incidence of developmental dysplasia of the hip by Chia H. Chang (5571032)

“…The results suggest that the health promotion policy is associated with an increase in early diagnosis and subsequently a decrease in surgeries for DDH.</p></div>…”