The increased chemotherapeutic retention in MDR cells treated for extended times with P-glycoprotein inhibitor 29 decreased cell survival as assessed by colony formation assays. by Amila K. Nanayakkara (6812384)

The scientific community’s tradition decreases both risk-taking and effort away from their productivity-maximizing actions while rewarding scientific contributions more evenly. by Kevin Gross (637614)

The actin nucleator Cobl decreases significantly in the ipsilateral hemisphere and in the primary motorcortex (M1) during the first hours after ischemic stroke induced by MCAO. by Yuanyuan Ji (455424)

Post-treatment controllers have very low levels of cell-associated HIV DNA which keep decreasing after treatment interruption for some patients. by Asier Sáez-Cirión (3141075)

Expression and distribution of p-JNK and JNK proteins in the P7 rat brain after HI as detected by Western blot analysis and fluorescence immunolabeling. by Deyuan Li (769599)

“…Equal levels of protein samples (100 μg) were loaded, and GAPDH served as a loading control. The values are expressed as the relative optical density and represented as the mean±SD (n = 5). …”

B-RAF inhibitor PLX-4720 decreased hERG current in <i>Xenopus</i> oocytes co-expressing hERG and B-RAF. by Tatsiana Pakladok (311653)

(a) Picture of one exposed rat with two fibromas (left)–(b) macroscopic view of the femoral tumour (right). by René de Seze (574047)

Effect of H5 (20 and 40 mg/kg, p.o.) and indomethacin (20 mg/kg, i.p.) on paw edema induced by carrageenan in mice. by Maria Alice Miranda Bezerra Medeiros (11752002)

<i>Mll2^Zp3</i> cKO oocytes show decreased H3K4 tri-methylation. by Claudia V. Andreu-Vieyra (243666)

Aliskiren (Ali) decreased expression of angiotensin II (Ang II) and attenuated steatosis and inflammation in the livers of mice fed with methionine choline deficiency (MCD) diet. by Kuei-Chuan Lee (383486)

Compound 52 reduced the ongoing spontaneous activity of C-fiber nociceptors but not Aδ-fiber nociceptors. by David J. Matson (625974)

Data Sheet 1_Kaurenoic acid is a potent inhibitor of SARS-CoV-2 RNA synthesis, virion assembly, and release in vitro.docx by Igor Andrade Santos (8556126)

“…Using an infectious virus, a larger reduction in the release of SARS-CoV-2 virions was observed. …”

Relationships between absolute value of latitude at collection site (x-axis) and date of first flowering (y-axis) for <i>Miscanthus sacchariflorus</i> (circles) and <i>M</i>. <i>sinsensis</i> and <i>M</i>. <i>floridulus</i> (diamonds) genotypes when grown in a greenhouse at Urbana, IL that provided decreasing day length of 1 min d^-1 via supplemental light from high intensity discharge (HID) lamps starting when natural day length reached 12.5 h (14 September). by Hongxu Dong (9955124)

HERVK HML-2 <i>env</i> knockdown decreases IFN-I expression and alters the secretory profile of THP1 monocytes and primary MDMs. by Natallia Mikhalkevich (10113822)

“…<p>(<b>A</b>) Transcription of HERVK HML-2 and five other HERV clades, identified upregulated by RNA-Seq in both irradiated THP1 cells and MDMs (<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1009305#ppat.1009305.g004" target="_blank">Fig 4A</a>), measured by RT-qPCR in THP1 cells expressing control (grey) or shRNA-Env (red), 48h post-irradiation. …”

HI promotes FOXO3a dephosphorylation, which induces FOXO3a translocation into the nucleus and upregulates the expression of Bim and CC3. by Deyuan Li (769599)

“…However, p-FOXO3a levels decreased from 0.5 to 48 h and returned to baseline at 72 h after HI (A). …”

Distribution of hookworm infections in different P/A/Ms from 2016 to 2019 according to the national surveillance in China. by Hui-Hui Zhu (6506063)

Decreased expression of microRNA-17 in hippocampal tissues and blood from mice with depression up-regulates the expression of PAI-1 mRNA and protein by Min Lv (608418)

Discovery and Pharmacological Studies of 4‑Hydroxyphenyl-Derived Phosphonium Salts Active in a Mouse Model of Visceral Leishmaniasis by José Ignacio Manzano (7908449)

“…We report the discovery of new 4-hydroxyphenyl phosphonium salt derivatives active in the submicromolar range (EC₅₀ from 0.04 to 0.28 μM, SI > 10) against the protozoan parasite Leishmania donovani. …”

Diaporaustalides A–L, Austalide Meroterpenoids from a Plant Endophytic <i>Diaporthe</i> sp. by Jin-Ling Chang (8752320)

“…Compounds <b>2</b> and <b>5</b> decreased the secretion of IL-6 in LPS-induced B cells in a dose-dependent manner.…”

Diaporaustalides A–L, Austalide Meroterpenoids from a Plant Endophytic <i>Diaporthe</i> sp. by Jin-Ling Chang (8752320)

“…Compounds <b>2</b> and <b>5</b> decreased the secretion of IL-6 in LPS-induced B cells in a dose-dependent manner.…”