DataSheet1_The interplay of common genetic variants NRG1 rs2439302 and RET rs2435357 increases the risk of developing Hirschsprung’s disease.PDF by Shuiqing Chi (10298891)

“…NRG1 and RET double mutants caused the most severe reduction in enteric neuron numbers than NRG1 single mutant or RET single mutant in the hindgut of zebrafish. SHSY-5Y cells and IPSCs with rs2439302 GG/rs2435357 TT genotype exhibited a decreased proliferative, migration, and differentiative capacity. …”

Table_1_Chemerin and PEDF Are Metaflammation-Related Biomarkers of Disease Activity and Obesity in Rheumatoid Arthritis.doc by Barbara Tolusso (146649)

“…Moreover, after low-calories diet, RA with low-moderate disease activity reaching BMI reduction ≥5% (62.6%) at 6 months had significant decrease of PEDF (p < 0.05) and Chemerin (p < 0.05) plasma values, in parallel with the improvement in disease activity.…”

Prospective Study of the Quality of Colonoscopies Performed by Primary Care Physicians: The Alberta Primary Care Endoscopy (APC-Endo) Study by Michael R. Kolber (428008)

“…Patient satisfaction was captured by a telephone survey.</p><p>Setting</p><p>Thirteen rural and suburban hospitals in Alberta, Canada.…”

Data_Sheet_1_From acidophilic to ornithogenic: microbial community dynamics in moss banks altered by gentoo penguins.pdf by Yevheniia Prekrasna-Kviatkovska (18117865)

“…The contrasting composition of peat and penguin feces led to the elimination of the initial peat microbiota, with an increase in Betaproteobacteria (from 1.3 ± 0.8% to 30.5 ± 23%) and Bacteroidota (from 5.5 ± 3.7% to 19.0 ± 3.7%) proportional to the intensity of penguins’ impact, accompanied by a decrease in community diversity. …”

Image_2_Chemerin and PEDF Are Metaflammation-Related Biomarkers of Disease Activity and Obesity in Rheumatoid Arthritis.pdf by Barbara Tolusso (146649)

“…Moreover, after low-calories diet, RA with low-moderate disease activity reaching BMI reduction ≥5% (62.6%) at 6 months had significant decrease of PEDF (p < 0.05) and Chemerin (p < 0.05) plasma values, in parallel with the improvement in disease activity.…”

Minimally Invasive Cardiac Surgery versus Sternotomy - Pain Investigation by Juliana Fernandes Silva (7292450)

“…In addition, patients subjected to MI procedure had a significant decrease in pain intensity from the third to the seventh PO days (p = 0.001). …”

Circular_0086414 induces SPARC like 1 (<i>SPARCL1</i>) production to inhibit esophageal cancer cell proliferation, invasion and glycolysis and induce cell apoptosis by sponging miR... by Qingfeng Jiang (9134096)

“…EC patients with low circ_0086414 expression had a poor prognosis. Increasing circ_0086414 expression led to decreased EC cell proliferation, invasion and glycolysis and increased cell apoptosis, accompanied by a decrease of N-cadherin expression and an increase of E-cadherin expression. …”

Image_3_Chemerin and PEDF Are Metaflammation-Related Biomarkers of Disease Activity and Obesity in Rheumatoid Arthritis.pdf by Barbara Tolusso (146649)

“…Moreover, after low-calories diet, RA with low-moderate disease activity reaching BMI reduction ≥5% (62.6%) at 6 months had significant decrease of PEDF (p < 0.05) and Chemerin (p < 0.05) plasma values, in parallel with the improvement in disease activity.…”

Table_1_HIV-1 and opiates modulate miRNA profiles in extracellular vesicles.docx by Allen Caobi (8858777)

“…SH-SY5Y cells, treated with xEVs derived from ART-treated PBMCs, exhibited increased viability while for SH-SY5Ys exposed to xEVs derived from HIV-1 infected PBMCs viability was decreased compared to the untreated control. …”

Data_Sheet_1_From acidophilic to ornithogenic: microbial community dynamics in moss banks altered by gentoo penguins.pdf by Yevheniia Prekrasna-Kviatkovska (18117865)

“…The contrasting composition of peat and penguin feces led to the elimination of the initial peat microbiota, with an increase in Betaproteobacteria (from 1.3 ± 0.8% to 30.5 ± 23%) and Bacteroidota (from 5.5 ± 3.7% to 19.0 ± 3.7%) proportional to the intensity of penguins’ impact, accompanied by a decrease in community diversity. …”

Simplified balance model of context-dependent effects of binding sites for transcriptional activators. by Kaiser J. Loell (17797684)

“…Stepwise addition of sites for a single TF first increase then decrease activity. …”

Fig 1 - by Simone Bach (9339740)

“…The genome harbors 7 protein genes whose mRNA expression levels (schematically shown below the genome, terminal dots indicating the 5’-cap) decrease from the first (NP) to the last (L) mRNA. …”

Modulation of Notch signaling affects axon outgrowth. by Ming Shi (78991)

“…(B–B'') Mis-expression of NICD results in a drastic decrease in the number of commissural axons crossing the midline. …”

Error-threshold exists in fitness landscapes with lethal mutants-0 by Nobuto Takeuchi (24907)

“…The notation and parameters are as follows (unless stated otherwise): The broken line is for = 0.05; the solid line is for = 0.5; the dotted line is for = 1.0; /= 0.99. Points (circles and plus signs) are calculated through the comparison of the first and second greatest eigen values of the model with back mutation [see "How high must lethality be to introduce an error-threshold" and Fig. 4(A) for details]. = 0.05 (the same as in Fig. 3) and = 0.99, unless stated otherwise. …”

IL1RAPL1 Associated with Mental Retardation and Autism Regulates the Formation and Stabilization of Glutamatergic Synapses of Cortical Neurons through RhoA Signaling Pathway by Takashi Hayashi (298480)

DataSheet1_Tanreqing Inhibits LPS-Induced Acute Lung Injury In Vivo and In Vitro Through Downregulating STING Signaling Pathway.DOCX by Yu-Qiong He (5568263)

Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling by Santiago Vilar (148764)

Selection for Unequal Densities of σ⁷⁰ Promoter-Like Signals in Different Regions of Large Bacterial Genomes by Araceli M Huerta (274811)

The protein architecture in <i>Bacteria</i> and <i>Archaea</i> identifies a set of promiscuous and ancient domains by Rafael Hernandez-Guerrero (5052308)

“…<div><p>In this work, we describe a systematic comparative genomic analysis of promiscuous domains in genomes of <i>Bacteria</i> and <i>Archaea</i>. …”

Image 1_Integrated analysis of microbiome and metabolome reveals insights into cervical neoplasia aggravation in a Chinese cohort.tif by Qingzhi Zhai (21265412)