Showing 901 - 920 results of 106,665 for search '(( 50 ((we decrease) OR (mean decrease)) ) OR ( 5 ((wt decrease) OR (a decrease)) ))', query time: 1.58s Refine Results
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    Transcriptomic and metabolomic analyses of liver of <i>Fmo5</i><sup><i>-/-</i></sup> and WT mice. by Ian R. Phillips (5074121)

    Published 2023
    “…<p>(A) Volcano plot representation of differentially expressed genes (log<sub>2</sub>-fold change) of <i>Fmo5</i><sup><i>-/-</i></sup> vs WT mice. …”
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    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

    Published 2021
    “…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”