Image_5_Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis.TIF by Byung Woo Kim (9658103)

“…Here, using CRISPR/Cas9 genome editing system and human induced pluripotent stem cells (iPSCs), we generated highly pure, iPSC-derived MNs with a SOD1-G93A missense mutation. With the wild-type cell line serving as an isogenic control and MNs from a patient-derived iPSC line with an SOD1-A4V mutation as a comparator, we identified pathological phenotypes relevant to ALS. …”

Binding of BDD-FVIII muteins to VWF (A-B) and to BO2C11 (C-G). by Jasper C. Lin (685807)

“…This mutein showed a ~100X faster off-rate and a 28-fold decreased affinity for BO2C11-Fab compared to WT-BDD-FVIII. …”

Custom-Made Spine Testing Apparatus. by Chunfeng Zhao (320370)

Table_3_A mouse model for X-linked Alport syndrome induced by Del-ATGG in the Col4a5 gene.xlsx by Wei-qing Wu (14758351)

“…The pathological changes included glomerular atrophy, increased monocytes in renal interstitial, and the absence of type IV collagen α5. The expression of Col4a5 was significantly decreased in Del-ATGG mouse model. …”

Table_2_A mouse model for X-linked Alport syndrome induced by Del-ATGG in the Col4a5 gene.xlsx by Wei-qing Wu (14758351)

“…The pathological changes included glomerular atrophy, increased monocytes in renal interstitial, and the absence of type IV collagen α5. The expression of Col4a5 was significantly decreased in Del-ATGG mouse model. …”

Table_1_A mouse model for X-linked Alport syndrome induced by Del-ATGG in the Col4a5 gene.xlsx by Wei-qing Wu (14758351)

“…The pathological changes included glomerular atrophy, increased monocytes in renal interstitial, and the absence of type IV collagen α5. The expression of Col4a5 was significantly decreased in Del-ATGG mouse model. …”

One-way migration distances calculated as mid–point to mid–point of their summer and winter geographic ranges. by Hector Galbraith (636637)

Data Sheet 2_Reducing ocular Demodex using petroleum jelly may alleviate dry eye syndrome, blepharitis, facial dermatoses, ocular and respiratory allergies, and decrease associated... by Diana E. Senior-Fletcher (22090340)

“…Mean yearly issues of anti-allergy and antimicrobial medicines reduced from 15.6 (range 8–25) to 1.8 (range 0–4), representing an 88.5% decrease for Volunteer 1 and from 5.8 (range 3–9) and 14.2 issues (range 9–24) to zero for both Volunteer 2 and Volunteer 13 respectively, representing 100% reductions in prescribing. …”

Data Sheet 1_Reducing ocular Demodex using petroleum jelly may alleviate dry eye syndrome, blepharitis, facial dermatoses, ocular and respiratory allergies, and decrease associated... by Diana E. Senior-Fletcher (22090340)

“…Mean yearly issues of anti-allergy and antimicrobial medicines reduced from 15.6 (range 8–25) to 1.8 (range 0–4), representing an 88.5% decrease for Volunteer 1 and from 5.8 (range 3–9) and 14.2 issues (range 9–24) to zero for both Volunteer 2 and Volunteer 13 respectively, representing 100% reductions in prescribing. …”

Frequency distributions of total prey weight per brood (g) in <i>Isodontia harmandi</i> nests collected for five years during 2010 to 2015. by Yui Imasaki (12562704)

Polymer ensemble from the simulations with the generic polymer model under the potential <i>V</i>_{<i>Polymer</i>} and spherical confinement. by Xiakun Chu (151393)

IF and IHC analysis of β-catenin in esophageal tissue from pediatric control (0–5 Eos/HPF) and EoE patients (>15 Eos/HPF). by Elizabeth Garcia (23115)

Distribution of overtaking crashes according to a set of independent variables. by Chun-Chieh Chao (2681722)

Clinical data of the control and CoA cases in our cohort. by Inmaculada Villanueva-Baxarias (21454246)

Diagram of a single copy gene (SCG) standard curve. by Raheleh Farahzadi (3860311)

Distribution of door crashes according to a set of independent variables. by Chun-Chieh Chao (2681722)

Infection parameters of Swiss mice infected with 50,000 trypomastigotes of the Y strain of <i>T</i>. <i>cruzi</i>. by Camila França Campos (360935)

“…(B) The mortality rate until the 20^th d.a.i. was significantly high, with death of approximately 50% of the animals treated with benznidazole. (C) The body mass of the chronic-phase infected group decreased compared with the control group but increased compared with the acute-phase infected group. …”

Spatial expression pattern of zebrafish <i>myc</i> genes in WT and MZ<i>spg</i> embryos at 60% epiboly. by Kay Kotkamp (539025)

“…<p>Whole mount <i>in situ</i> hybridization (WISH) analysis of <i>myca</i>, <i>mycb</i>, <i>mych</i>, <i>mycl1a</i> and <i>mycl1b</i> expression in WT (right embryo in each panel) and MZ<i>spg</i> (left embryo in each panel). …”

ASMR (A), ASDR (B), Age-Standardized Rate of YLDs (C), and Age-Standardized Rate of YLLs (D) of high alcohol use-related Stroke in both sexes combined in global and five SDI region... by Nannan Qian (10650782)

Socioeconomic disparities and sexual dimorphism in neurotoxic effects of ambient fine particles on youth IQ: A longitudinal analysis by Pan Wang (198097)

“…Increased ambient PM_2.5 levels were associated with decreased IQ scores. …”