Clostridium difficile toxins or infection induce upregulation of adenosine receptors and IL-6 with early pro-inflammatory and late anti-inflammatory pattern by D.A. Foschetti (10461345)

Non-Pneumatic Anti-Shock Garment (NASG), a First-Aid Device to Decrease Maternal Mortality from Obstetric Hemorrhage: A Cluster Randomized Trial by Suellen Miller (294598)

“…We hypothesized the NASG group would have a 50% reduction in adverse outcomes.…”

Heatmaps with different genetic linkage and migration rate. by Georg Oberhofer (3401438)

“…More generally, the data from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009385#pgen.1009385.g006" target="_blank">Fig 6A–6F</a> show that within the range of migration rates shown (0.5%-4%), increased rates of migration must be counterbalanced by decreased recombination frequency (increased drive strength and duration) in order for <i>Rescue</i>/Cargo/gRNAs to be maintained at high frequency. …”

Detection of epistasis is rescued by simultaneous analysis of multiple independently-evolved populations. by Gabriele Pedruzzi (5753792)

Image_5_Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation.JPEG by Huimin Deng (1844299)

“…Notably, the abundance of Bacteroides fragilis was reported to be significantly decreased in CDAD patients. This study aimed to clarify the prophylactic effects of B. fragilis strain ZY-312 in a mouse model of C. difficile infection (CDI). …”

Table_5_Balance Adaptation While Standing on a Compliant Base Depends on the Current Sensory Condition in Healthy Young Adults.DOCX by Stefania Sozzi (9193071)

DataSheet1_Potential causal associations of PM2.5 and osteoporosis: a two-sample mendelian randomization study.docx by Yi Zhang (9093)

“…</p><p>Results: The results indicated that PM2.5 was not correlated with a decrease in FN-BMD (β: −0.305, 95%CI: −0.762, 0.153), LS-BMD (β: 0.134, 95%CI: −0.396, 0.666), FA-BMD (β: -0.056, 95%CI: −1.172,1.060), and HE-BMD (β: −0.084, 95%CI: −0.261,0.093). …”

Image_1_A highly susceptible hACE2-transgenic mouse model for SARS-CoV-2 research.PDF by Gang Liu (81776)

“…Overexpression of hACE2 did not pose a significant effect on weight growth. After SARS-CoV-2 inoculation, mice showed obvious viral replication and production of inflammation within 7 days, with a gradual decrease in body weight until death. …”

Image_5_Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation.JPEG by Huimin Deng (1844299)

“…Notably, the abundance of Bacteroides fragilis was reported to be significantly decreased in CDAD patients. This study aimed to clarify the prophylactic effects of B. fragilis strain ZY-312 in a mouse model of C. difficile infection (CDI). …”

Image 5_Risk factors for thoracic aortic aneurysm and dissection among diabetic patients: a nationwide population-based study.tif by Suk Kyung Lim (22382302)

Table_5_Nutrient Scarcity in a New Defined Medium Reveals Metabolic Resistance to Antibiotics in the Fish Pathogen Piscirickettsia salmonis.pdf by Javiera Ortiz-Severín (8273808)

DataSheet_1_Canavanine-Induced Decrease in Nitric Oxide Synthesis Alters Activity of Antioxidant System but Does Not Impact S-Nitrosoglutathione Catabolism in Tomato Roots.pdf by Pawel Staszek (7407689)

“…Treatment with CAN (10 or 50 µM) for 24–72 h led to restriction in root growth. …”

Table_1_Resveratrol enhances A1 and hinders A2A adenosine receptors signaling in both HeLa and SH-SY5Y cells: Potential mechanism of its antitumoral action.docx by Sonia Muñoz-López (11369454)

“…Interestingly, these effects were almost identical in HeLa and SH-SY5Y cells suggesting that resveratrol enhances A₁ and hinders A_2A adenosine receptors signaling as part of a potential mechanism of antitumoral action.…”

Table_5_Effect of BAFF blockade on the B cell receptor repertoire and transcriptome in a mouse model of systemic lupus erythematosus.xlsx by Tao Huang (110613)

A Multi-scale Computational Platform to Mechanistically Assess the Effect of Genetic Variation on Drug Responses in Human Erythrocyte Metabolism - Fig 5 by Nathan Mih (3146436)

Image_5_PvdQ Quorum Quenching Acylase Attenuates Pseudomonas aeruginosa Virulence in a Mouse Model of Pulmonary Infection.pdf by Putri D. Utari (5143832)

“…We then treated mice with PvdQ during lethal P. aeruginosa pulmonary infection and that resulted in a 5-fold reduction of lung bacterial load and a prolonged survival of the infected animals with the median survival time of 57 hin comparison to 42 h for the PBS-treated group. …”

Video5_Experimental constraints on the stability and oscillation of water vapor film—a precursor for phreatomagmatic and explosive submarine eruptions.MP4 by Ingo Sonder (13895760)

Pelvis and femur shape prediction using principal component analysis for body model on seat comfort assessment. Impact on the prediction of the used palpable anatomical landmarks a... by Léo Savonnet (7314200)

“…Results also show that the PCA based method is a good alternative to predict hip and lumbosacral joint centers with an average error of 5.0 and 9.2 mm respectively.…”

The N-terminal low complexity and PUF domains of Puf3 are critical for interaction with Pbp1. by Floortje van de Poll (15810877)

“…Note that <i>NtΔ</i> and <i>PUFΔ</i> mutants of Puf3 are unstable and expressed at lower levels compared to WT. Transcript levels are shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010774#pgen.1010774.s005" target="_blank">S5 Fig</a>.…”

Birds invest wingbeats to keep a steady head and reap the ultimate benefits of flying together by Lucy A. Taylor (492318)

“…Here, we compared the flight characteristics of homing pigeons (<i>Columba livia</i>) flying solo and in pairs released from a site 7 km from home, using high-precision 5 Hz global positioning system (GPS) and 200 Hz tri-axial accelerometer bio-loggers. …”