Table_1_Association between serum iron levels and atherosclerotic cardiovascular diseases among American older adults: a cross-sectional study based on the National Health and Nutr... by Xiaochen Yu (3796927)

Table_1_The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Ra... by Philip C. Spinella (5181788)

“…Background<p> The hemostatic properties of tranexamic acid (TXA) are well described, but the immunological effects of TXA administration after traumatic injury have not been thoroughly examined. We hypothesized TXA would reduce monocyte activation in bleeding trauma patients with severe injury.…”

The Cost-Effectiveness of Intermittent Preventive Treatment for Malaria in Infants in Sub-Saharan Africa by Lesong Conteh (231114)

DataSheet1_The AKT inhibitor, MK-2206, attenuates ABCG2-mediated drug resistance in lung and colon cancer cells.ZIP by Hai-Ling Gao (9501677)

“…However, MK-2206 (0.3 and 1 μM) significantly increased the anticancer efficacy of mitoxantrone, SN-38 and topotecan, in H460/MX20 and S1-M1-80 cancer cells, as indicated by a significant decrease in their IC50 values, compared to cells incubated with vehicle. …”

Data_Sheet_1_Excess Mortality in Italy During the COVID-19 Pandemic: Assessing the Differences Between the First and the Second Wave, Year 2020.PDF by Maria Dorrucci (252694)

“…During the first wave (25th February−31st May), we estimated 52,437 excess deaths (95% CI: 49,213–55,863) and 50,979 (95% CI: 50,333–51,425) during the second phase (10th October−31st December), corresponding to percentage 34.8% (95% CI: 33.8%–35.8%) in the second wave and 31.0% (95%CI: 27.2%–35.4%) in the first. …”

Results of the Implementation of a Pilot Model for the Bidirectional Screening and Joint Management of Patients with Pulmonary Tuberculosis and Diabetes Mellitus in Mexico by Martín Castellanos-Joya (630597)

Data_Sheet_1_Concerted suppressive effects of carisbamate, an anti-epileptic alkyl-carbamate drug, on voltage-gated Na+ and hyperpolarization-activated cation currents.docx by Te-Yu Hung (15861305)

“…The effective IC₅₀ values of CRS for the differential suppression of transient (I_Na(T)) and late I_Na (I_Na(L)) were 56.4 and 11.4 μM, respectively. …”

Data_Sheet_2_Excess Mortality in Italy During the COVID-19 Pandemic: Assessing the Differences Between the First and the Second Wave, Year 2020.PDF by Maria Dorrucci (252694)

“…During the first wave (25th February−31st May), we estimated 52,437 excess deaths (95% CI: 49,213–55,863) and 50,979 (95% CI: 50,333–51,425) during the second phase (10th October−31st December), corresponding to percentage 34.8% (95% CI: 33.8%–35.8%) in the second wave and 31.0% (95%CI: 27.2%–35.4%) in the first. …”

Table_1_Sirt1 Promotes a Thermogenic Gene Program in Bone Marrow Adipocytes: From Mice to (Wo)Men.DOCX by Hanna Artsi (777390)

“…To investigate the role of Sirtuin1 (Sirt1), a key player in metabolism, in MAT, marrow adiposity was evaluated in inbred 5-month-old 129/Sv Sirt1 haplo-insufficient (Sirt1^Δ/+) and wild type (WT) mice. …”

<i>VHL-KO</i> mice exhibit hypoglycemia despite normal glucose tolerance and intact pancreatic β cells. by Atsushi Kurabayashi (156793)

“…<p>(<b>A</b>) <i>VHL-KO</i> mice had significant decreases in blood glucose levels (BS) after tamoxifen injection (4 mg/mouse; n = 10). …”

Image_1_Sirt1 Promotes a Thermogenic Gene Program in Bone Marrow Adipocytes: From Mice to (Wo)Men.TIF by Hanna Artsi (777390)

“…To investigate the role of Sirtuin1 (Sirt1), a key player in metabolism, in MAT, marrow adiposity was evaluated in inbred 5-month-old 129/Sv Sirt1 haplo-insufficient (Sirt1^Δ/+) and wild type (WT) mice. …”

DataSheet1_Superlubricity of pH-responsive hydrogels in extreme environments.PDF by Allison L. Chau (13235433)

“…The swelling behavior and elastic modulus of these polyelectrolyte hydrogels were highly sensitive to solution pH and poorly predicted the friction coefficient (µ), which decreased with increasing AA concentration. P(AAm-co-AA) hydrogels with the greatest AA concentrations (12 wt%) exhibited superlubricity (µ = 0.005 ± 0.001) when swollen in unbuffered, deionized water (pH = 7, I = 0 M) and 0.5 M NaOH (pH = 13.8, I = 0.25 M) (µ = 0.005 ± 0.002). …”

PolyQ expansion affects p53-dependent apoptotic function in cells and in zebrafish. by Hongmei Liu (129385)

“…The ratio of embryos with the representative phenotypes was indicated. Both <i>WT</i> and <i>80Q</i> mRNA injections resulted in obvious <i>otx2</i> signal decreases in <i>p53 WT</i> but not <i>p53 mutant</i> zebrafishes, with more profound <i>otx2</i> signal reduction in <i>80Q</i> mRNA injections. …”

Rac1 inhibition specifically affects the dynamics of paxillin in adhesions. by Nicholas O. Deakin (164000)

“…FRAP analyses reveal a significant increase in the immobile fraction of GFP-paxillin, but not vinculin-YFP in cells with decreased Rac1 activity. Error bars are standard error of the mean. * = p<0.05.…”

Effect of H3 haplotype on serum HDL-cholesterol levels in women. by Heidi J. Silver (324097)

“…In obese females, calorically restricted (−15% kcal) HF diet increased HDL-C from 50.11±11.60 mg/dl to 52.29±10.38 mg/dl in H3 haplotype carriers and decreased HDL-C from 47.99±12.90 mg/dl to 45.49±8.95 mg/dl in H3 non-carriers.…”

Presentation_1_Characterization, Hypoglycemic Activity, and Antioxidant Activity of Methanol Extracts From Amomum tsao-ko: in vitro and in vivo Studies.pdf by Libin Xie (12075542)

“…PMEAT solution was found to have potent α-glucosidase-inhibiting activity (IC₅₀, 0.145 mg/mL) in vitro, twice as strong as that of acarbose (IC₅₀, 0.273 mg/mL). …”

Analysis of the inner ear cell type–specific transcriptome. by Ronna Hertzano (203344)

Silencing of miR-214 induces apoptosis in NPC cells. by Zi-Chen Zhang (511377)

Assessment of transcriptome associated with endothelium activation and blood-brain barrier integrity. by Nana O. Wilson (399957)

PA28αβ silencing increases mHTT aggregation in ST<i>Hdh</i> cells. by Karlijne W. Geijtenbeek (14304969)