Example of skyline query for proteins. by Rizka Fatriani (17485787)

“…The stability of the protein-ligand complex resulting from docking was examined using molecular dynamics simulations, and we observed the best average root mean square deviation (RMSD) of 0.99 Å for PPARG with trans-3-indoleacrylic acid, which was lower than with the native ligand BRL (2.02 Å). …”

Top 10 pathways with the lowest p-value. by Rizka Fatriani (17485787)

“…The stability of the protein-ligand complex resulting from docking was examined using molecular dynamics simulations, and we observed the best average root mean square deviation (RMSD) of 0.99 Å for PPARG with trans-3-indoleacrylic acid, which was lower than with the native ligand BRL (2.02 Å). …”

Pseudocode of block-nested loop (BNL). by Rizka Fatriani (17485787)

“…The stability of the protein-ligand complex resulting from docking was examined using molecular dynamics simulations, and we observed the best average root mean square deviation (RMSD) of 0.99 Å for PPARG with trans-3-indoleacrylic acid, which was lower than with the native ligand BRL (2.02 Å). …”

Top 10 gene ontologies with the lowest p-value. by Rizka Fatriani (17485787)

“…The stability of the protein-ligand complex resulting from docking was examined using molecular dynamics simulations, and we observed the best average root mean square deviation (RMSD) of 0.99 Å for PPARG with trans-3-indoleacrylic acid, which was lower than with the native ligand BRL (2.02 Å). …”

hCDC-derived exosomes significantly decrease cardiomyocyte programed cell death and cause a trend toward increased proliferation of cardiomyocytes <i>in vitro</i> at one week in cu... by Jennifer K. Lang (344441)

Coalescence of a Ferrofluid Drop at Its Bulk Surface with or without a Magnetic Field by Qindan Zhang (7343165)

Pairwise comparisons of hormonal results for DMPA-IM vs NET-EN expressed as mean percentage differences (95% CI) (mITT analysis). by Chanel Avenant (409756)

<i>N</i>⁶-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herp... by Charles R. Hesser (5147309)

“…In iSLK.219 cells the defect was linked to their roles in the post-transcriptional accumulation of the major viral lytic transactivator ORF50, which is m⁶A modified. In contrast, although the ORF50 mRNA was also m⁶A modified in KSHV infected B cells, ORF50 protein expression was instead increased upon depletion of METTL3, or, to a lesser extent, YTHDF2. …”

Predictive values of IC₅₀ in mM (FFAs) for vanadium compounds and <i>in vivo</i> observations IC₅₀ in mM (FFAs) and decreasing blood glucose level. by Elena V. Fedorova (603922)

<em>RAD50</em> Is Required for Efficient Initiation of Resection and Recombinational Repair at Random, γ-Induced Double-Strand Break Ends by Jim Westmoreland (260234)

“…Unlike for enzymatically induced site-specific DSBs, little is known about processing of random “dirty-ended” DSBs created by DNA damaging agents such as ionizing radiation. Here we present a novel system for monitoring early events in the repair of random DSBs, based on our finding that single-strand tails generated by resection at the ends of large molecules in budding yeast decreases mobility during pulsed field gel electrophoresis (PFGE). …”

Top 50 genes whose expression is most decreased in PN11 <i>Klf5</i>CN compared with the WT corneas. by Doreswamy Kenchegowda (135193)

Top 50 genes whose expression is most decreased in PN56 <i>Klf5</i>CN compared with the WT corneas. by Doreswamy Kenchegowda (135193)

Susceptibility of half knockout strains to CYP51 inhibitors (EC50, μM): compounds with decreased activity on HKO + CYP strains. by Laura-Isobel McCall (222498)

DataSheet1_Familial Hypercholesterolemia: Real-World Data of 1236 Patients Attending a Czech Lipid Clinic. A Retrospective Analysis of Experience in More than 50 years. Part I: Gen... by Veronika Todorovova (12157917)

“…Our data represent retrospective analysis of 50 years of specialised care in our center.</p><p>Patients and Methods: A group of 1236 FH patients (841 women, 395 men; 993 study subjects and 243 relatives; mean age 44.8 ± 16.7 years) included 154 FDB patients followed at the Lipid Clinic of the General University Hospital in Prague since the mid-1960s to the present. …”

Decreased peritumoral myofibroblasts in the MC38 S.C. tumors of <i>S100a4-Cre; Ext1</i>^<i>f/f</i> mice. by Ayumi Niwa (6256790)

DataSheet_2_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…Introduction<p>Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. …”

DataSheet_1_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…Introduction<p>Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. …”

KDM6A mRNA expression is decreased in PTFE mice. by Simon Lebek (9756148)

Reduced cellular glucose uptake in response to insulin and decreased expression of a mitochondrial ETC complex subunit in <i>ALAS1</i>-knockdown C2C12 myocytes. by Shinichi Saitoh (4794345)

Molecular Mimics of Classic P-Glycoprotein Inhibitors as Multidrug Resistance Suppressors and Their Synergistic Effect on Paclitaxel by Moustafa E. El-Araby (3626396)

“…On the other hand, combination of PTX and the non-cytotoxic Cur1-12V (10 μM) significantly decreased the IC₅₀ of PTX to 3.8 nM as well as the resistant fraction to 16.2%. …”