Kylo-0603’s EC50 & tissue levels. حسب Xueqin lu (22250795)

MBIC50 and MBEC50 values (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives against bacteria pathogen strains. حسب Jean Paul Dzoyem (6424445)

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Intravital 2-photon microscopy imaging of acute <i>C</i>. <i>albicans</i> infections of the kidney in real time in a living host. حسب Fitz Gerald S. Silao (9384713)

Drive dynamics for split^<50cM <i>ClvR</i>s with different genetic linkage and migration rates. حسب Georg Oberhofer (3401438)

Alpha-smooth muscle actin (ASMA) is decreased and vimentin is increased in smooth muscle cells (SMCs) isolated from non-dilated bicuspid aortic valve (BAV)-associated aortas. حسب Brittany Balint (6829967)

Bacterial load in lung and spleen of binge-drinking mice intranasally infected with decreasing doses of <i>B</i>. <i>thailandensis</i>. حسب Victor M. Jimenez Jr. (8107853)

Non-hematopoietic IFN-γ response results in decrease expression of hepatic CXCR3 on T lymphocytes. حسب Tamir Diamond (12822347)

Oral administration of TVSE decreases angiogenesis in 4T1 tumors in BALB/c mice. حسب Hyun Sook Lee (8039876)

Insufficient disulfide bond formation results in a decrease in alkaline phosphatase activity and accumulation of the reduced form of DegP in LCFA-utilizing cells. حسب Kanchan Jaswal (9542107)

"…The band corresponding to AP is shown (Mol. wt. ~50 kDa). <i>(C) Compromised DsbA-DsbB machinery is responsible for the decrease in alkaline phosphatase activity in cells utilizing oleate</i>. …"

miR-200c decreases KLOTHO expression in HK-2 cells by translational repression. حسب Kenichi Morii (6843554)

HE and non-HE applications. حسب Caitlin E. Burgdorf (17965486)

Prognosis and risk factors of chronic kidney disease progression in patients with diabetic kidney disease and non-diabetic kidney disease: a prospective cohort CKD-ROUTE study حسب Shengnan Chen (3595319)

"…The secondary endpoints were all-cause death and the development of cardiovascular disease (CVD) events. We found that DKD patients have a higher risk to develop 50% eGFR decline endpoint (HR:2.30, 95%CI [1.48–3.58], <i>p</i> < 0.001) and KRT endpoint (HR:1.64, 95%CI [1.13–2.37], <i>p</i> < 0.05) than NDKD patients. …"

Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor حسب Beatrice Noce (16540800)

"…We found that <b>9a</b>, bearing a pargyline moiety, is also able to selectively inhibit MAOB over MAOA (465-fold) with an IC₅₀ of 0.182 μM, being the first-in-class dual NOX2/MAOB covalent inhibitor. …"

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma حسب Zhihao Liu (419349)

"…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …"

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma حسب Zhihao Liu (419349)

"…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …"

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma حسب Zhihao Liu (419349)

"…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …"

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation حسب Kairui Yue (11874403)

"…In this study, we report the first highly selective HDAC6 inhibitor with hydrazide as the zinc-binding group (ZBG), which displays superior pharmacokinetic properties to the current hydroxamic acid inhibitors. …"

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation حسب Kairui Yue (11874403)

"…In this study, we report the first highly selective HDAC6 inhibitor with hydrazide as the zinc-binding group (ZBG), which displays superior pharmacokinetic properties to the current hydroxamic acid inhibitors. …"

Discovery of Triazolyl Derivatives of Cucurbitacin B Targeting IGF2BP1 against Non-Small Cell Lung Cancer حسب Fan-Fan Shang (16953264)

"…Cucurbitacin B (CuB) is a potent but toxic anticancer natural product. Herein, we designed and synthesized 2-OH- and 16-OH-modified CuB derivatives to improve their antitumor efficacy and reduce toxicity. …"

PCR-RFLP detection results of the three new SNPs (g.-1293C>G, g.56T>C, g.7017C>T) in bovine <i>C3</i> gene. حسب Yonghui Wang (287491)

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