Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades حسب Ihab Shawish (13015516)

الموضوعات:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades حسب Ihab Shawish (13015516)

الموضوعات:

Extracted ion chromatogram of azoxystrobin 50 ppb, injection volume of 2, 5, and 25 μL. حسب Ekramy Halawa (11785086)

Crosslinking decreases the alignment of fibers associated with individual cells migrating out of spheroids. حسب Michael Pamonag (12295175)

Decreasing fluconazole susceptibility of clinical South African <i>Cryptococcus neoformans</i> isolates over a decade حسب Serisha D. Naicker (8648370)

Transcriptional and translational markers of syncytialization and biochemical differentiation are significantly decreased by rotenone. حسب O’Llenecia S. Walker (8486163)

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses حسب Jing Wang (6206297)

"…By compiling a global data set of 1,782 paired observations from 185 publications, we show that land use conversion from natural to managed ecosystems significantly reduced NNM by 7.5% (−11.5, −2.8%) and increased NN by 150% (86, 194%), indicating decreasing N availability while increasing potential N loss through denitrification and nitrate leaching. …"

Ce6 decreases the amount of TMV PQS5 upon photo-irradiation. حسب Congbao Xie (17599247)

GSK343 decreased tumor stemness. حسب Laura V. Bownes (10276762)

"…(C) COA6 cells were treated with GSK343 (0, 5 μM) for 72 hours. qPCR demonstrated a significant decrease in mRNA abundance of known stemness markers Oct4, Nanog, and Sox2 following GSK343 treatment compared to untreated cells. …"

Comparison of the decrease of CFU in CSF and blood between treatment groups within the first 6 h after treatment. حسب Luca G. Valente (12463057)

mGluR5 receptor decreased glycinergic currents. حسب Zi-Yang Zhang (4988555)

"…(<b>E</b>) The inhibitory effect of CHPG on GlyR-IPSCs was not blocked by intracellularly loaded GDP-β-S (62.3 ± 6.4% of baseline at 15–20 min post-CHPG, <i>t</i>[6] = 2.782, <i>p</i> = 0.032), chelerythrine (60.9 ± 11.3% of baseline at 15–20 min post-CHPG, <i>t</i>[6] = 2.705, <i>p</i> = 0.035), or Ro-32-0432 (69.9 ± 3.2% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 8.495, <i>p</i> < 0.001). (<b>F</b>) Postsynaptic loading of U-0126 or PD98059 prevented CHPG from decreasing glycinergic responses (U-0126, 107.6 ± 10.4% of baseline at 15–20 min post-CHPG, <i>t</i>[8] = 0.997, <i>p</i> = 0.348; PD98059, 93.1 ± 5.0% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 0.883, <i>p</i> = 0.418). …"

One-way sensitivity analysis, <i>Immediate ART</i> strategy compared to <i>ART<350/μL</i>. حسب Eric N. Ouattara (6890174)

The first regression of log of confirmed cases vs consecutive days for 4 of the total of 50 countries is shown. حسب Adam Kaplin (10156481)

Retinoic acid decreases intracellular K⁺ in pectoral fin buds via transcriptional activation of the calcineurin inhibitor <i>rcan2</i>. حسب Xiaowen Jiang (8291814)

ABT199 inhibits ALK ^mutant kinase activity and decreases it phosphorylation. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Cost-effectiveness and budget impact of immediate antiretroviral therapy initiation for treatment of HIV infection in Côte d’Ivoire: A model-based analysis حسب Eric N. Ouattara (6890174)

"…<i>Immediate ART</i> increased the 5-year HIV care budget from $801.9M to $812.6M compared to <i>ART<350/μL</i>.…"

Multi-way sensitivity analysis on transmission rate, CD4 count at diagnosis, and ART costs in a model-based analysis of Immediate ART initiation in Côte d’Ivoire. حسب Eric N. Ouattara (6890174)

TUDCA decreases ER stress in HOX neonatal rat lungs. حسب Kirkwood A. Pritchard Jr. (13449794)

"…(<b>C</b>) In IHC stain, P-IRE1α levels are decreased (40.8±3.5 A.U. <i>vs</i> 53.1±5.0 A.U., p<0.001, n = 6, 3 for each sex) in chronic hyperoxia exposed neonatal rat lungs by TUDCA. …"

Repeated LSPC treatment prolongs survival of and decreases PrP^Res accumulation in a subset of prion-infected mice. حسب Heather Bender (363996)

The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties. حسب Wangyong Shin (6793040)

"…<i>n</i> = 4 oocytes for WT (EC₅₀ = 1.75 ± 0.04 μM) and 3 oocytes for C456Y (EC₅₀ = 1.86 ± 0.02 μM), <i>P</i> = 0.23, Mann-Whitney. …"