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10941
Data Sheet 6_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for...
Published 2025“…Between 1990 and 2021, the global age-standardized mortality rate (ASDR) decreased from 15.6 to 12.4 per 100,000, and the age-standardized DALY rate declined from 357.3 to 283.2 per 100,000. …”
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10942
Data Sheet 3_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for...
Published 2025“…Between 1990 and 2021, the global age-standardized mortality rate (ASDR) decreased from 15.6 to 12.4 per 100,000, and the age-standardized DALY rate declined from 357.3 to 283.2 per 100,000. …”
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10943
Data Sheet 1_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for...
Published 2025“…Between 1990 and 2021, the global age-standardized mortality rate (ASDR) decreased from 15.6 to 12.4 per 100,000, and the age-standardized DALY rate declined from 357.3 to 283.2 per 100,000. …”
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10944
Data Sheet 2_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for...
Published 2025“…Between 1990 and 2021, the global age-standardized mortality rate (ASDR) decreased from 15.6 to 12.4 per 100,000, and the age-standardized DALY rate declined from 357.3 to 283.2 per 100,000. …”
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10945
Data_Sheet_1_Potential lipid-lowering effects of Ulmus macrocarpa Hance extract in adults with untreated high low-density lipoprotein cholesterol concentrations: A randomized doubl...
Published 2022“…</p>Results<p>UME over 12 weeks led to a greater decrease in LDL-C, TC, and ApoB concentrations than did the placebo as follows: by 18.1 mg/dl (P < 0.001); 23.3 mg/dl (P < 0.001); 9.3 mg/dl (P = 0.018), respectively. …”
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10946
Under microaerobic (1% O<sub>2</sub>) conditions in free living cells, the hFixL-FxkR-FixK pathway and not FnrN is a key activator of anaerobox controlled genes.
Published 2021“…The <i>hfixL</i><sub>9</sub> homolog had a far more pronounced effect on expression of all three genes than did the <i>hfixL</i><sub>c</sub> homolog. …”
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10947
The effects of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) transplantation on renal function (A and B) and renal histology (C to G) of NOD-SCID mice treated with...
Published 2013“…Three days after folic acid, renal tubular cell damage was severe in folic acid-injured NOD-SCID mice (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046504#pone-0046504-g002" target="_blank">Figure 2E</a>) and administration of hUC-MSCs to folic acid-injured NOD-SCID mice could decrease renal tubular cell damage (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046504#pone-0046504-g002" target="_blank">Figure 2F</a>). …”
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10948
Manipulation of AMPK pathway affects performance in the LGMD/DCMD circuit.
Published 2014“…<p>(<b>A</b>). Metformin application (arrow) results in a decreased responsiveness to repeated looming stimuli. …”
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10949
Export flux succession of dinoflagellate cysts and planktonic foraminifera in an active upwelling cell off Cape Blanc (NW Africa)
Published 2021“…<p>To better understand production, succession, excystment and transport of dinoflagellate cysts (dinocysts) and planktonic foraminifera in the upper water column, we investigated their fluxes during a 7-day survey in the active upwelling off Cape Blanc (NW Africa) in November 2018 with drifting traps at 100 m, 200 m and 400 m water depth. …”
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10950
Image_4_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.png
Published 2019“…Two-electrode voltage clamp analysis on oocyte-expressed nAChR subtypes demonstrated the functionality of these peptides but also revealed a 30 to 100-fold potency decrease of expressed TxIA compared to chemically synthesized TxIA. …”
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10951
Image_2_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.JPEG
Published 2019“…Two-electrode voltage clamp analysis on oocyte-expressed nAChR subtypes demonstrated the functionality of these peptides but also revealed a 30 to 100-fold potency decrease of expressed TxIA compared to chemically synthesized TxIA. …”
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10952
Image_1_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.JPEG
Published 2019“…Two-electrode voltage clamp analysis on oocyte-expressed nAChR subtypes demonstrated the functionality of these peptides but also revealed a 30 to 100-fold potency decrease of expressed TxIA compared to chemically synthesized TxIA. …”
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10953
Image_3_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.JPEG
Published 2019“…Two-electrode voltage clamp analysis on oocyte-expressed nAChR subtypes demonstrated the functionality of these peptides but also revealed a 30 to 100-fold potency decrease of expressed TxIA compared to chemically synthesized TxIA. …”
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10954
Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1α and VEGF recept...
Published 2017“…</p><p>Methods</p><p>AGS (gastric cancer), Caco-2 (colorectal cancer) and HepG2/C3A (hepatocellular carcinoma), were treated with telomerase inhibitors BIBR-1232 (10μM) and costunolide (10μM), with bevacizumab (Avastin® at 5 ng/ml or 100μg/ml) or with a combination of both types of inhibitors. …”
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10955
C2GnT1 mediates invasion.
Published 2013“…(B) Similarly, decreased invasion was observed for HepG2 cells that were transfected with C2GnT1 shRNA compared to transfection with a control vector, *p = 0.0005. …”
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10956
Biomass and water use efficiency of chrysanthemum under organic, mineral, and organomineral fertilization
Published 2023“…The greenhouse experiment was conducted in a 5 × 2 factorial randomized block design with five fertilization managements (incubated wood ash, non-incubated wood ash, organomineral, mineral fertilization, and control) and two liming values (0 and 100% of the recommendation), with five replicates. …”
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10957
Use of sugar cane to feed lactating dairy goats
Published 2021“…The experimental diets were composed of increasing levels (0, 33, 66 and 100%) of substitution in dry matter (DM). Twelve multiparous Saanen goats, with an average body weight of 45.2kg, average milk yield of 3.0kg day-1, distributed in a triple latin square experimental design (4 × 4) were used. …”
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10958
Morin, a Bioflavonoid Suppresses Monosodium Urate Crystal-Induced Inflammatory Immune Response in RAW 264.7 Macrophages through the Inhibition of Inflammatory Mediators, Intracellu...
Published 2016“…For comparison purpose, colchicine was used as a reference drug. We have observed that morin (100–300 μM) treatment significantly suppressed the levels of inflammatory cytokines (TNF-α, IL-1β, IL-6, MCP-1 and VEGF), inflammatory mediators (NO and PEG<sub>2</sub>), and lysosomal enzymes (acid phosphatase, β-galactosidase, N-acetyl glucosamindase and cathepsin D) in MSU-crystals stimulated macrophage cells. …”
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10959
Data Sheet 1_Excess mortality in young cancer survivors compared with the general population in Italy: a retrospective study from the Italian population-based cohort of adolescents...
Published 2025“…Young adult cancer survivors face a sevenfold increase in all-cause mortality compared to the general population, with a notable rise in both cancer-related and non-cancer deaths. …”
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10960
Optimal reductions in EDP compared to the baseline level.
Published 2023“…The analogous figure to A, but with <i>P</i><sub><i>S</i></sub> = 100 sentinels added to the population and results corresponding to the strategies identified in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010884#pcbi.1010884.g003" target="_blank">Fig 3C</a>. …”