Metalloproteinases cleave CD13 from the surface of FLS. by Rachel L. Morgan (3132747)

“…Cultures were incubated with serum free media containing protease inhibitors for 48 hours: Pepstatin A (aspartic) 10μM, Aprotinin (serine) 100nM, Leupeptin (serine/cysteine) 10μM, GM6001 (metalloproteinase) 25μM, and E-64 (cysteine) 10μM. …”

Parasitemia titration results. by Paul Lebel (11250722)

“…<p>Logscale plots a-b,d-f contain shaded regions corresponding to nominal mean parasitemia plus or minus one standard deviation of the underlying Poisson distribution when counting N total cells, where N is varied from 100 up to 100,000 in roughly 3× increments. …”

DataSheet1_Eluxadoline Versus Antispasmodics in the Treatment of Irritable Bowel Syndrome: An Adjusted Indirect Treatment Comparison Meta-analysis.PDF by Di Qin (107446)

“…The secondary efficacy outcome was the relief of global IBS symptoms, defined by a composite response of a decrease in abdominal pain and improvement in stool consistency on the same day for at least 50% of the days assessed. …”

Table_1_Repurposing of Rutan showed effective treatment for COVID-19 disease.DOCX by Shavkat I. Salikhov (17471622)

“…Here, our re-purposing study demonstrated that Rutan at 25, 50, and 100 mg/kg provided a very effective and safe treatment for COVID-19 infection, simultaneously inhibiting two vital enzyme systems of the SARS-CoV-2 virus: 3C-like proteinase (3CLpro) and RNA-dependent RNA polymerase (RdRp). …”

Data_Sheet_1_Repurposing of Rutan showed effective treatment for COVID-19 disease.docx by Shavkat I. Salikhov (17471622)

“…Here, our re-purposing study demonstrated that Rutan at 25, 50, and 100 mg/kg provided a very effective and safe treatment for COVID-19 infection, simultaneously inhibiting two vital enzyme systems of the SARS-CoV-2 virus: 3C-like proteinase (3CLpro) and RNA-dependent RNA polymerase (RdRp). …”

MF induced EGFR interaction. by Xia Wu (203682)

“…The plots represent the FI along wavelength in FRET groups of FL cells treated with sham exposure for 30 min (Sham), 0.4 mT 50 Hz MF for 30 min (MF), 100 nM EGF for 30 min while sham exposed (EGF) or 0.4 mT 50Hz MF exposed (MF+EGF), or pretreated with 1 μM PD for 2 h before 30 min treatment of 100 nM EGF (PD+EGF) or 0.4 mT 50 Hz MF (PD+MF). …”

Exosin inhibits ExoS ADPRT activity. by Anthony Arnoldo (42511)

“…(B) Dose-response curve for E216-5303 on the ADPRT activity of ExoS. Various aliquots of a stock solution of E216-5303 prepared in DMSO were pre-incubated with 20 µM human Ras, 1 µM of FAS and 20 µM of ε-NAD⁺ in 100 mM NaCl, 2 mM MgCl₂, 200 mM sodium acetate, pH 6.0. …”

Treatment of pFTY720 in vivo or in vitro reduces MOG reactive splenocyte-induced demyelination isolated from MOG-immunised mice. by Adam J. Pritchard (575041)

“…<p>(A) MOG reactive splenocytes isolated from MOG-immunised animals treated with pFTY720 (8 µg/day, for 10 days) <i>in vivo</i> or treated with pFTY720 (1 nM) during re-stimulation <i>in vitro</i> with 25 µg/ml MOG prevented demyelination caused by these isolated cells. …”

PHOSPHORUS FERTILIZATION AND SOIL TEXTURE AFFECT POTATO YIELD by JÉSSYCA DELLINHARES LOPES MARTINS (6117419)

“…The treatments were represented by four P rates (10, 50, 100, and 200 mg dm-3 P) and two soil textures (clayey and sandy). …”

Hemodialysis-Related Glycemic Disarray Proven by Continuous Glucose Monitoring: Glycemic Markers and Hypoglycemia by Akinori Hayashi (305316)

“…</p> <p><b>RESULTS</b></p> <p>Sensor glucose level (SGL) showed a sustained decrease during HD, irrespective of the dialysate glucose concentration, and reached a nadir that was lower than the dialysate glucose concentration in 49 participants (50%). …”

DataSheet_1_Microglia Susceptibility to Free Bilirubin Is Age-Dependent.docx by Ana Rita Vaz (6566963)

“…Cells were isolated from the cortical brain of 1- to 2-day-old CD1 mice and incubated for 24 h with 50/100 nM Bf levels, which were associated to moderate and severe neonatal hyperbilirubinemia, respectively. …”

OSM activates ERK-1/2, SAPK/JNK-1/2 MAP kinases, the PI3-kinase Akt and STAT1/3 in HCT116 cells and STAT3 activation is dependent of the LIFR. by Florian Beigel (174724)

“…One representative experiment (n = 3) is shown. IL-22 (100 ng/mL), for which we previously demonstrated STAT1 and STAT3 activation in IEC <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0093498#pone.0093498-Brand3" target="_blank">[44]</a>, served as positive control. …”

The effect of hydroxychloroquine on lupus erythematosus-like skin lesions in MRL/lpr mice by Tatsuya Shimomatsu (1545943)

“…<p><i>Objectives</i>: To evaluate the effect and safety of hydroxychloroquine (HCQ) on lupus erythematosus (LE)-like skin lesions in the MRL/lpr mouse, a model for systemic LE (SLE).</p> <p><i>Methods</i>: We divided the MRL/lpr mice into three groups that were given: (1) drinking water, (2) HCQ at a dose of 4 mg/kg/d, or (3) HCQ at a dose of 40 mg/kg/d. …”

Data_Sheet_1_Quantifying Pesticide Exposure Risk for Monarch Caterpillars on Milkweeds Bordering Agricultural Land.PDF by Paola Olaya-Arenas (6841796)

“…For thiamethoxam, isolating milkweeds 50–100 m from the nearest corn or soybean field tended to decrease the concentration and likelihood of detecting residues, whereas landscape composition surrounding milkweed sites had comparatively weak predictive power. …”

Effect of prolactin on the phosphorylation of Ca-dependent PKC isoforms by Silvia Taffetani (77822)

“…</p><p></p> Immunoblots for PKC-α, PKC-β-I, PKC-β-II and PKC-γ in normal female cholangiocytes stimulated for 90 minutes at 37°C with 0.2% BSA (basal value) or prolactin (100 nM) with 0.2% BSA. When cholangiocytes were treated with prolactin, there was an increase in the phosphorylation of PKCβ-I and a marked decrease in PKCα phosphorylation; no significant changes in the phosphorylation of PKCβ-II and PKCγ were observed in normal female cholangiocytes treated with prolactin or 0.2% BSA. …”

Arp2 Hydrolyzes ATP Rapidly upon Filament Nucleation by Mark J Dayel (70485)

“…<div><p>(A) Arp2/3 (2 μM) was covalently crosslinked to γ-³²P-AzidoATP by exposure to UV light. …”

Figure 5 from Shortwave Infrared Imaging Enables High-Contrast Fluorescence-Guided Surgery in Neuroblastoma by Laura Privitera (16015972)

“…<b>D,</b> MFI of anti–GD2-IR800 and anti–GD2-IR12 decrease towards longer wavelengths. The shaded region represents SE over pixels in ROI. …”

miR-27b regulates ASC-mediated suppression of CFSE-labeled allogeneic CD4⁺ T cell proliferation. by Kuang-Den Chen (322973)

“…The cells were then cultured with Con A (1 µg/ml) (as 100% proliferation) and Con A + with different ratios of ASCs (1∶10, 1∶5, 1∶1, ASCs:T cells) with α-miR-27b or α-miRNC transfection. …”

Binding of insulator factors to DNA. by Jutta Vogelmann (622973)

“…In contrast to BEAF32, CP190 shifted the three DNA fragments with similar efficiency even at high protein concentrations (400 nM). Concentrations used were: 0, 100, 200, 300 and 400 nM, respectively. …”

Real-time PCR quantifications in the presence of primers with different annealing abilities. by Michele Guescini (169183)

“…Specifically, the PCRs were set as follows: 1) 500 nM ND1F2; 2) 375 nM ND1F2 and 125 nM ND1F5; 3) 250 nM ND1F2 and 250 nM ND1F5; 4) 200 nM ND1F2 and 300 nM ND1F5; 5) 150 nM ND1F2 and 350 nM ND1F5; 6) 125 nM ND1F2 and 375 nM ND1F5; 7) 100 nM ND1F2 and 400 nM ND1F5; 8) 50 nM ND1F2 and 450 nM ND1F5; and 9) 500 nM ND1F5. …”