Muscle-specific knockdown of <i>nSMase</i> minimally decreases glucosylceramide levels, which are globally elevated in <i>Gba1b</i> mutants. by Kathryn A. Jewett (3756811)

Decreased membranous expression of p120ctn in DBPDE-induced premalignant and cancer lesions. by Douglas B. Stairs (9574800)

TGFβ1 expression was increased, and RASAL1 expression was decreased in NTM cells in response to a hypoxic environment. by Fiona McDonnell (2636635)

“…<p>We examined mRNA expression of TGFβ1 and RASAL1 by qPCR and protein expression by Western blotting under normoxic (21%O₂) and hypoxic conditions (1%O₂). <b>A.</b> qPCR showed an apparent increase in TGFβ1 mRNA expression in cells subjected to hypoxia after 6 hours; fold change in gene expression was 1.37+/-0.16. …”

Anti-inflammation decreases promoter methylation and restores <i>p21</i> expression. by B. R. Achyut (280274)

“…<p>(A) Decreased CpG 16 methylation of p21 promoter from forestomach samples of <i>Tgfbr2^fspKO</i> mice treated with Celecoxib (n = 3). …”

Key findings from the 16 studies included in the present review regarding the effect of PPE fit on performance of (A) body armour; (B) gloves; (C) helmets; (D) spacesuits; and (E)... by Brooke R. Brisbine (14197451)

DAF-16/FOXO is Required for Locomotory Healthspan and Lifespan Benefits of Genetic Glycolysis Disruption. by Brian Onken (86790)

“…WT later in life [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref091" target="_blank">91</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref092" target="_blank">92</a>]; we note that, although comparison of scores across experiments is not possible due to variation in baseline values, the swimming rate of <i>daf-16(mgDf50)</i> control animals was slightly lower than WT controls on the same day of life (in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.g001" target="_blank">Fig 1C</a>; mean of 46.17 head thrashes/30 sec. for <i>daf-16</i> vs. 52.17 head thrashes/30 sec. for WT on day 10). …”

Distribution of sequencing base mass (A) and sequencing base content (B) in each sample. by Xu Jia (187142)

Activated CD8 T cells in FOXO3−/− mice display decreased apoptosis. by Jeremy A. Sullivan (183868)

<i>EVL</i> Expression Is Decreased with Increasing Tumor Grade in Breast Carcinoma by Timothy A Chan (49811)

Schematic model: IFI16 inhibits HSV-1 gene expression by modulating histone modifications and binding to HSV-1 promoters, specifically preventing or decreasing the association of t... by Karen E. Johnson (655281)

Acute Snail knockout decreases the numbers of neural precursors and neurons in the embryonic cortex. by Mark A. Zander (618326)

“…Arrows indicate EGFP-negative cells with robust nuclear Snail immunoreactivity, and arrowheads denote EGFP-positive cells with decreased Snail staining. Scale bar 20 µm. (B) Fluorescence micrographs of coronal sections through E16/17 control or Cre-electroporated cortices immunostained for EGFP (green). …”

PS1 downregulation in new neurons decreases dendritic arborization and spine density. by Jacqueline A. Bonds (358407)

“…<b>C, D</b>. PS1 downregulation results in decreased number of spines <b>(C)</b> as a function of increasing distance from the soma (two-way ANOVA (treatment and distance from soma) F_{(treatment)1,60} = 13.10, P<0.001, F_{(distance)19,60} = 3.18, P<0.001) and mean spine density <b>(D)</b> (unpaired t-test, *P<0.05). …”

Female ρ1 (−/−) mice showed decreased ethanol conditioned taste aversion. by Yuri A. Blednov (396502)

The three hit compounds decrease bacterial load of <i>Salmonella</i> in mammalian cells. by Abigail L. Reens (5349746)

Mean and standard deviation values for the magnitude of first peak (Fy1) during running shod (SH) and barefoot (BF), in both PRE and POST training, where (^a) means diffe... by Ana Paula da Silva Azevedo (3373688)

Equipment for fresh hide packing using vacuum (A) and the packed hide samples (B). by Ilze Gudro (659771)

CXCR4 blockade decreased the percentage of PD-1 expressing adaptive immune cells in sepsis. by Kimberly M. Ramonell (4678906)

“…<p><b>(A-B)</b> Representative flow plots (gated on CD3 cells) demonstrating PD-1 expression in CD4⁺ T cells and CD8⁺ T cells. …”

Loss of virulence in the SIN kinase mutants is characterized by decreased fungal burden and host response to infection. by Ana Camila Oliveira Souza (8180958)

“…<p><b>A)</b> Analysis of fungal burden by qPCR at day +4 post inoculation. …”

Decrease in gastrin-, histidine decarboxylase-, and somatostatin mRNA due to the <i>H. pylori</i> B128 WT-infection. by Tobias Wiedemann (266622)

A flowchart showing the number of women participating in the RCT. by Sigrid Nilsson (12647302)

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