Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein inter... حسب Thirumal Kumar, D.

"…From the analysis, we observed the highest deviation with lowest compactness and a decrease in the intramolecular h-bonds in the BRCA1-BARD1 protein complex with the V11G mutation compared to the native complex or the complexes with other mutations. 2022 Elsevier Inc.…"
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Degradation of 4-chlorophenol through cooperative reductive and oxidative processes in an electrochemical system حسب Yang, Kaichao

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Utilization of Emergency Services by Children with Asthma in Qatar حسب Arafah, Dima

"…Background: Asthma is a leading chronic disease in children worldwide, which if left untreated or poorly controlled, can lead to altered lung function and poor quality of life. 1 Early detection and improved control of asthma are recommended to decrease utilization of emergency services and hospitalizations. …"
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Barriers and Motivators of Appropriate Antibiotic Prescription at PHCC in Qatar: Perspective of Physicians and Pharmacists حسب Sharaf, Nahla

"…Antimicrobial resistance (AMR) is a serious public health problem of global concern. …"
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Barriers and motivators of appropriate antibiotic prescription at PHCC in Qatar: perspective of physicians and pharmacists حسب Sharaf, Nahla

"…Antimicrobial resistance (AMR) is a serious public health problem of global concern. …"
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Cultivating microalgae in desert conditions: Evaluation of the effect of light‐temperature summer conditions on the growth and metabolism of nannochloropsis qu130 حسب Jabri, Hareb Al

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Salicylic acid restricts mercury translocation by activating strong antioxidant defense mechanisms in sweet pepper (Capsicum annum L.) حسب Khalid, Muhammad Fasih

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Low electro-synthesis potentials improve permselectivity of polymerized natural phenols in biosensor applications حسب Monti, Patrizia

"…The natural phenol-coated electrodes were stable and responsive throughout 14 days. A biosensor prototype based on acetylcholine esterase and choline oxidase was electro-coated with poly-magnolol in order to evaluate the interference-rejecting properties of the electrosynthesized film in an amperometric biosensor; a moderate decrease in ascorbic acid rejection was observed during in vitro calibration of biosensors.…"
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Bone benefits of fish oil supplementation depend on its EPA and DHA content حسب Abou-Saleh H.

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Synthesis of silica supported ni and cu catalyst for carbon dioxide methanation reaction حسب Aheed, Ahmed

"…In this study we investigate the synthesis of nickel and copper catalyst supported on silica for CO2 conversion to methane. …"
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Design and analysis of PV fed high-voltage gain DC-DC converter using PI and NN controllers حسب Madisa V.G., Varaprasad

"…When the converter switch comes under active state two capacitors are discharged in series, similarly when the converter switch under inactive state those two capacitors are charged in parallel through the coupled inductor (CI) energy so, to get a high voltage at the converter output side. To reuse the leakage-inductor (LI) energy of the CI with the help of a passive clamp circuit for reducing the voltage stress across the switch, similarly switch has less resistance so conduction losses also decreased. …"
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STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS حسب AL-SADEQ, DUAA WALID

"…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …"
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A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase حسب Thirumal Kumar, D

"…Considering true positives, true negatives, false positives, and false negatives, three mutations (Y114E, R128G, and C145A) showed "loss of DNA repair activity," and were analyzed further using molecular dynamics simulations (MDS) using GROMACS for 50ns. MDS run showed that the C145A mutant demonstrated higher structural deviation, decreased compactness, and the binding patterns. …"
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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics حسب Nomikos, Michail

"…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …"
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Online monitoring of climatic parameters: a statistical study about environmental changes in Qatar حسب Mahmood, Tahir

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Driver Drowsiness Detection Study using Heart Rate Variability analysis in Virtual Reality Environment حسب Chowdhury, Muhammad E.H.

"…The LF/HF ratio reflects the differences between awake and drowsy states while the ratio was decreasing gradually from the awake state to drowsy state [5-6].Method A portable wireless BioRadio (Fig.2 A) (Great Lakes NeuroTechnologies, Inc.) …"
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Investigation of Magnesium (II), Calcium (II) and Barium (II) Complexes in Aqueous Solution حسب Bakr, Mustafa Farag [مصطفى فرج بكر]

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Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria حسب Al-Sadeq, Duaa W.

"…We observed that the disease-associated K72I genetic variant had no apparent effects on the spectroscopic and catalytic properties of the full-length enzyme. …"
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Novel Isosteviol Derivatives Induced Apoptosis In Human Lung Cancer حسب Malki, Ahmed

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Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway حسب Anwar, M. Akhtar

"…Prior exposure to PI3K inhibitors, wortmannin (0.1 µM) or LY294002 (10 µM), decreased cGMP accumulation and attenuated the SF-induced vasorelaxation by approximately 50% (Rmax). …"
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