Inhibition of Pig Phosphoenolpyruvate Carboxykinase Isoenzymes by 3-Mercaptopicolinic Acid and Novel Inhibitors by Jorge Hidalgo (145178)

“…Its inhibition patterns were the same for both isoenzymes: a three-fold decrease of the K_i values for GTP in 139Met and 139Leu (273 and 873 μM, respectively). …”

Figure S1 - SUMOylation Regulates the Transcriptional Repression Activity of FOG-2 and Its Association with GATA-4 by José Perdomo (114665)

“…Co-transfection of the indicated SUMO E3 ligases did not increase FOG-2 SUMOylation (lanes 2 to 5, right panel). In fact there was a decrease in FOG-2 SUMOylation in the presence of Ubc9 (lane 7, left panel) or E3 ligases (lanes 2 to 5, right panel). …”

EBNA1 can self-associate through its UR1 domain. by Siddhesh Aras (263042)

“…The scale bars indicate a length of 10 microns. The fraction of fluorescent cells observed under each condition in five independent measurements is shown along with the standard deviation. …”

DataSheet_1_Effects of diet and temperature on the fatty acid composition of the gammarid Gammarus locusta fed alternative terrestrial feeds.docx by Alberto Ribes-Navarro (9973753)

“…The temperature had no effect on biomass, although high temperature (20°C) resulted in a decrease in survival. The effects of temperature on the gammarid fatty acids were not evident, with diet being the main modulator of the profiles. …”

C57BL substrain differences in generalized seizure thresholds. by Sridhar B. Kadiyala (529914)

“…<p>The latency to a generalized seizure (generalized seizure threshold (GST)) on each seizure trial was determined for 5 C57BL substrains (n = 12 mice/substrain: 10SNJ, 10J, 6J, 6NJ, and KSJ) by exposure to 10% flurothyl during eight induction trials followed by a 28-day rest period and a single flurothyl retest. …”

Image_2_Hepatitis C virus alters the morphology and function of peroxisomes.TIF by Esther Martin de Fourchambault (17017134)

“…In an APEX2-based proximity biotinylation screen, we identified ACBD5, a peroxisome membrane protein, as located in the vicinity of HCV replication complexes. …”

Rain-Shelter Cultivation Modifies Carbon Allocation in the Polyphenolic and Volatile Metabolism of <i>Vitis vinifera</i> L. Chardonnay Grapes by Yuan Gao (159945)

“…In addition, the rain-shelter cultivation significantly enhanced the synthesis of fatty acid-derived volatiles, isoprene-derived terpenoids and amino acid-derived branched-chain aliphatics, but led to a decrease in the accumulation of isoprene-derived norisoprenoids and amino acid-derived benzenoids. …”

Plant health and quality of Eucalyptus urophylla x Eucalyptus grandis seedlings receiving phosphite and silicon application by Thiago Tássio de Sousa Silva (7501391)

“…At 120 days, seedlings of all treatments, except control, had adequate survival rate, evidencing a positive effect of treatments on this variable, which is of great economic importance for a commercial nursery.…”

Distribution patterns of Platycodon grandiflorus from the last inter-glacial period to the future by ecological niche modeling by Chunjiao Li (19159480)

“…The results indicated: (1) The species' distribution strongly correlates with environmental variables, particularly bio13, prec07, prec09 and tmin07, whose cumulative value of percent contribution was 78.5%; (2) The centroids of potential geographic distribution during the LIG, LGM, and MH periods were situated further westward compared tothe present distribution, with substantial contraction observed in highly suitable habitats throughout these historical periods; (3) Under present climatic conditions, the overall suitable habitat encompasses4,185,964 km2, withhighly suitable habitats constitutingone-third of this expanse, predominantlyconcentrated in central, southern, and northeasternChina; (4) Future climate change scenarios predict that the total suitable habitat will expand to varying degrees (7% increase on average), albeit with potential reductions in highly suitable areas (3% decrease on average); (5) The distribution of P. grandiflorus is likely to move towards higher latitudes in the future due to climate changes. …”

Table1_MYLK*FLNB and DOCK1*LAMA2 gene–gene interactions associated with rheumatoid arthritis in the focal adhesion pathway.DOCX by Maëva Veyssiere (6433154)

“…We identified 9 significant interactions involving 11 genes (MYLK, FLNB, DOCK1, LAMA2, RELN, PIP5K1C, TNC, PRKCA, VEGFB, ITGB5, and FLT1). One interaction (MYLK*FLNB) increasing RA risk and one interaction decreasing RA risk (DOCK1*LAMA2) were confirmed in a replication sample (200 unrelated RA cases and 91 GBR unrelated controls). …”

DataSheet1_MYLK*FLNB and DOCK1*LAMA2 gene–gene interactions associated with rheumatoid arthritis in the focal adhesion pathway.pdf by Maëva Veyssiere (6433154)

“…We identified 9 significant interactions involving 11 genes (MYLK, FLNB, DOCK1, LAMA2, RELN, PIP5K1C, TNC, PRKCA, VEGFB, ITGB5, and FLT1). One interaction (MYLK*FLNB) increasing RA risk and one interaction decreasing RA risk (DOCK1*LAMA2) were confirmed in a replication sample (200 unrelated RA cases and 91 GBR unrelated controls). …”

<strong>Contrasting exogenous and endogenous soil microbial carbon use efficiencies under global changes</strong> by Andong Cai (5237024)

“…Invasive plants significantly decreased microbial CUEex by 11.5%. Global change enhanced the microbial growth rate by 6.5%; however, when combined with added exogenous carbon there was a decrease of 3.2%. …”

CRF-induced anxiety-like behavior is mediated by the dynorphin/KOR system. by Michael R. Bruchas (255614)

“…<p><b><i>A</i></b>, CRF injection (1 µg, i.c.v., 30 min prior to assay) produced a significant anxiety-like effect (decrease in % open arm time) in the elevated plus maze (EPM) compared with saline injected controls. …”

Table_1_Chronic constant light exposure aggravates high fat diet-induced renal injury in rats.docx by Lin Xing (7384631)

“…And, constant light exposure caused an increase in HIF1α and a decrease in prolyl hydroxylase domain 1 (PHD1) and PHD2 expression in kidneys of HFD-fed rats. …”

CStS recapitulate MSNs degeneration observed in R6/2 mouse model. by Catia C. Proenca (431486)

“…Neurodegeneration is observed as a decrease in marker intensity. F) Left: quantification for the ratio of striatal NeuN and DAPI positive nuclei in WT and R6/2 slices at DIV21. …”

Additional file 2 of Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate–induced colitis in mice lacking microsomal prostag... by Fumiaki Kojima (11905683)

“…A significant decrease in food uptake was observed in mPGES-1−/− mice during DSS administration over 7 days, indicating severe symptoms of colitis in mPGES-1−/− mice. …”

Erratum: Pharmacokinetics, Pharmacodynamics, and Safety of Single-Dose Rivaroxaban in Chronic Hemodialysis by Dias C. (4162003)

“…In 8 subjects with ESRD, a 15-mg dose of rivaroxaban was administered 2 ± 0.5 h before a hemodialysis session and repeated 7-14 days later at 3 h after a 4-h hemodialysis session. …”

Pituitary Adenylate Cyclase Activating Peptide (1-38) and its analog (Acetyl-[Ala15, Ala20] PACAP 38-polyamide) reverse methacholine airway hyperresponsiveness in rats by Mounira Tlili (12847046)

“…Male Wistar rats were divided randomly into five groups. Groups 1 and 2 inhaled respectively aerosols of saline or increasing doses of MeCh (0.5, 1, 2.12, 4.25, 8.5, 17, 34 and 68mg/L). …”

Image_4_Hepatitis C virus alters the morphology and function of peroxisomes.TIF by Esther Martin de Fourchambault (17017134)

“…In an APEX2-based proximity biotinylation screen, we identified ACBD5, a peroxisome membrane protein, as located in the vicinity of HCV replication complexes. …”

Image_3_Hepatitis C virus alters the morphology and function of peroxisomes.TIF by Esther Martin de Fourchambault (17017134)

“…In an APEX2-based proximity biotinylation screen, we identified ACBD5, a peroxisome membrane protein, as located in the vicinity of HCV replication complexes. …”