Data_Sheet_1_Enterovirus 71 Suppresses miR-17-92 Cluster Through Up-Regulating Methylation of the miRNA Promoter.docx by Yuxuan Fu (4437475)

“…Overexpression of hsa-miR-17∼92 inhibited, while inhibition of endogenous hsa-miR-17∼92 facilitated EV71 replication. We identified two sequences located at nt 3024 to 3038 and nt 2838 to 2862 of the EV71 (strain FY0805) genome as potential targets for hsa-miR-17-5p and miR-19a/b, respectively, which were validated by luciferase reporter assays and Western blot. …”

ROC curves of TAS + SOD + MDA to diagnose PCG. by Mingxi Shao (10066570)

“…The XGBoost or KNN model using TAS alone achieved the highest AUC (0.74) in five-fold cross-validation.</p><p>Conclusion</p><p>The decrease in TAS levels and the increase in H₂O₂ and MDA levels are found to be correlated with PCG, and the results indicate that oxidative stress plays a part in congenital glaucoma onset.…”

The chromatin remodelling protein LSH/HELLS regulates the amount and distribution of DNA hydroxymethylation in the genome by Maud De Dieuleveult (10764288)

“…We further show that differentially hydroxymethylated regions did not completely overlap with differentially methylated regions indicating that changes in 5hmC distribution upon <i>Lsh</i> knock-out are not a direct consequence of 5mC decrease. …”

OMT by Jingmin Ou (19669426)

“…OMT was found to significantly increase the apoptosis rate of endothelial cells (ECs) treated with oxidised low-density lipoprotein (ox-LDL), as measured by caspase-3 activity assay and flow cytometry. qRT-PCR results showed that OMT treatment decreased the expression of miR-199a-5p in ECs.Transfection of miR-199a-5p mimics enhanced the apoptotic effect, whereas miR-199a-5p inhibitors attenuated apoptosis, suggesting that miR-199a-5p has a key regulatory role in EC apoptosis. …”

Jackknife analysis of the top environmental predictors used in the model. by Kylie M. Sage (4543402)

Differential expression of microRNA-411 and 376c is associated with hypertension in pregnancy by Hui-li Yang (6572189)

Data_Sheet_1_Adaptation of Respiratory-Related Brain Regions to Long-Term Hypercapnia: Focus on Neuropeptides in the RTN.pdf by Ayse Sumeyra Dereli (8122871)

“…Animal studies have demonstrated an initial (within hours) increase in ventilatory drive followed by a decrease in this response over the long-term (days–weeks) in response hypercapnia. …”

Supplementary Material for: Tofacitinib as Induction and Maintenance Therapy in Japanese Patients with Active Ulcerative Colitis by Suzuki Y. (3596711)

“…In OCTAVE Sustain (NCT01458574), 39 patients with clinical response in OCTAVE Induction 1 were re-randomized to placebo, tofacitinib 5 mg, or 10 mg b.i.d. Efficacy endpoints included: remission (primary endpoint; total Mayo score ≤2; no individual subscore >1; rectal bleeding subscore 0); mucosal healing (Mayo endoscopic subscore ≤1); clinical response (≥30% and ≥3-point decrease from induction study baseline total Mayo score; decrease in rectal bleeding subscore ≥1 or absolute subscore ≤1). …”

Data_Sheet_1_Cerebral Oxygenation During Neonatal Intubation–Ancillary Study of the Prettineo–Study.PDF by Meryl Vedrenne-Cloquet (6415619)

“…The two primary outcomes were a decrease in rScO₂ value >20% from baseline and a decrease in fractional cerebral tissue oxygen extraction (FTOE) value >10% from baseline, at any time point. …”

Image_1_Cerebral Oxygenation During Neonatal Intubation–Ancillary Study of the Prettineo–Study.TIFF by Meryl Vedrenne-Cloquet (6415619)

“…The two primary outcomes were a decrease in rScO₂ value >20% from baseline and a decrease in fractional cerebral tissue oxygen extraction (FTOE) value >10% from baseline, at any time point. …”

The relationship between trophic structure and producer nutrient content. by Just Cebrian (265900)

“…<p>(A, B) The relationships between the ratio of herbivore-to-producer biomass (H∶P, in g C m⁻² ∶ g C m⁻²) and producer nitrogen and phosphorus contents. …”

<b><i>Acropora intermedia</i></b> genome by Wentao Han (12381793)

“…</i><i> </i><i>intermedia</i> obtained through PacBio Hi-Fi long-read sequencing, with a total genome size of 473 Mb. Compared to the previous version, our assembly shows substantial improvements in contiguity, with the Contig N50 increasing from 40.3 Kb to 2.9 Mb, and the total number of scaffolds decreasing from 6,224 to 633. …”

Data_Sheet_1_Ultra-Low Oxygen and Preconditioning Storage Regulate Ethylene Synthesis to Prevent Corky Disorders in ‘Fuji’ Apple.docx by Camila Riaño (12693314)

“…In addition, a considerable reduction in ethylene production for up to 30 days was observed in ULO-treated fruit at 0 and 5^°C. …”

Cytoprotective gene regulation is essential to lifespan extension by diverse mechanisms. by David E. Shore (123998)

“…Only 5 of the 29 gene inactivations result in a 15% or greater reduction in wild-type (N2) lifespan, and most (20 of 29) reduce wild-type lifespan by less than 10% (column 5). …”

<b><i>Differential impacts of asymmetric winter warming and symmetric year-round warming on leaf nutrient and resorption in an alpine meadow</i></b> by Huanhuan Song (12835471)

Mitigation of memory impairment in AD model mice by oral administration of Hop extracts. by Norio Sasaoka (282209)

“…(D) Morris water maze test with V717F mice. The test measured the time required for mice to locate a hidden platform. …”

Table_1_Circulating Reelin promotes inflammation and modulates disease activity in acute and long COVID-19 cases.pdf by Laurent Calvier (3339327)

“…Finally, we tested Reelin inhibition with the anti-Reelin antibody CR-50 in hACE2 transgenic mice infected with SARS-CoV-2. …”

Somatic expression of <i>lin-35(+)</i> partially rescues <i>lin-35</i> mutant fertility defects. by Brian P. Mikeworth (16274376)

The <i>I</i>_K1/Kir2.1 channel agonist zacopride prevents and cures acute ischemic arrhythmias in the rat by Xu-Wen Zhai (4033601)

“…In all the three treatment modes, zacopride (15 μg/kg) inhibited MI-induced ventricular tachyarrhythmias, as shown by significant decreases in the premature ventricular contraction (PVC) and the duration and incidence of VT or VF. …”

Video 1_Quantitative comparisons of pulmonary artery hemodynamics before and after Pulsta valve implantation in patients with Tetralogy of Fallot using computational fluid dynamics... by Seung Min Baek (13994226)

“…After PPVI, the vorticity (RPA; 3.9–1.6/s, p = 0.008, LPA; 4.4–1.8/s, p = 0.011, MPA; 5.4–1.5/s, p = 0.008), and energy dissipation (104.1–38.1 mW, p = 0.028) decreased significantly, whereas changes in the Womersley and Reynolds numbers were not statistically significant. …”