Showing 541 - 560 results of 103,597 for search '(( 50 ((we decrease) OR (nn decrease)) ) OR ( 5 ((mg decrease) OR (a decrease)) ))', query time: 1.22s Refine Results
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    Pre-administration of metformin 3 days before irradiation significantly decreases the number of micronuclei in murine bone marrow cells and the number of DNA damage foci in colon a... by Silvia Siteni (10344070)

    Published 2024
    “…<p>(A) Metformin 200 mg/kg pre-administration significantly decreases the number of micronuclei in mice bone marrow cells, compared to the 7.5 cGy control, in 129/sv mice one-way ANOVA, **p<0.01, ****p<0.0001). …”
  13. 553

    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

    Published 2021
    “…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
  14. 554

    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

    Published 2021
    “…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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    A. We randomly selected 20 mutually exclusive groups of protein complexes that contained exactly five subunits; we mapped the corresponding gene pairs to SINaTRA scores, and plotte... by Alexandra Jacunski (5665486)

    Published 2015
    “…A SINaTRA cutoff of 0.95 has approximately half of its pairs associated with the same complex; however, a decrease in the cutoff shifts this balance. …”
  17. 557

    Decreased Tks5 expression results in neural crest-derived defects. by Danielle A. Murphy (212554)

    Published 2011
    “…<p>(A–B) Melanophores within the trunk region above the yolk sac extension in control MO-injected and Tks5 MO-injected embryos were qualitatively (A) and quantitatively (B) analyzed. n = 15 embryos and SEM is shown by bar. p values obtained from Student's t-test. ** denotes p<0.01. …”
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    Dose-Finding Study of Omeprazole on Gastric pH in Neonates with Gastro-Esophageal Acid Reflux Using a Bayesian Sequential Approach by Florentia Kaguelidou (373190)

    Published 2016
    “…</p><p>Intervention</p><p>Five preselected doses of oral omeprazole from 1 to 3 mg/kg/day.…”