Closed-loop insulin therapy for people with type 2 diabetes treated with an insulin pump: a 12-week multicenter, open-label randomized controlled crossover trial by Anne-Laure Borel (444715)

HCC cell lines with repaired AXIN1 mutation show reduced β-catenin signaling. by Ruyi Zhang (38360)

Table_2_Impact of traditional Chinese Baduanjin exercise on menstrual health among international female students studying in China: a randomized controlled trial.DOC by Asem Alkhatib (11244708)

“…In addition, the results of the MANOVA indicated statistically significant decreases in scores for the two subscales of MSQ: premenstrual symptoms (intervention: 17.07 ± 3.33 vs. control: 28.42 ± 7.56; F = 44.70, P < 0.01)and menstrual pain (16.03 ± 4.53 vs. 19.58 ± 5.14; F = 6.50, P < 0.05). …”

Table_1_Impact of traditional Chinese Baduanjin exercise on menstrual health among international female students studying in China: a randomized controlled trial.DOC by Asem Alkhatib (11244708)

“…In addition, the results of the MANOVA indicated statistically significant decreases in scores for the two subscales of MSQ: premenstrual symptoms (intervention: 17.07 ± 3.33 vs. control: 28.42 ± 7.56; F = 44.70, P < 0.01)and menstrual pain (16.03 ± 4.53 vs. 19.58 ± 5.14; F = 6.50, P < 0.05). …”

Roles of varying protein and choline nutrient contents in very high fat, low protein, very low carbohydrate diet-induced hepatic steatosis. by Rebecca C. Schugar (452038)

“…Data are presented as means±SEM. <i>a</i>, significant difference compared to chow; <i>b</i>, significant difference attributable to decrease in protein content (from 10% kcal to 5% kcal) at a fixed choline content; <i>c</i>, significant difference attributable to restriction in choline content (from 5.3 g/kg to 0.3 g/kg) at a fixed protein content; by 1-way ANOVA with Tukey’s post hoc testing.…”

Effects of tPA and cilostazol on endothelial cells at 18 h after reperfusion. by Mitsunori Ishiguro (359127)

“…Western blot analysis measured the levels of claudin-5. tPA alone at 6 h decreased claudin-5 levels. …”

Metabolic parameters of mice maintained on very high fat, low protein, very low carbohydrate diets. by Rebecca C. Schugar (452038)

“…For all panels, data are presented as means±SEM. <i>a</i>, significantly different compared to chow; <i>b</i>, significant difference attributable to decrease in protein content (from 10% kcal to 5% kcal) at a fixed choline content; <i>c</i>, significant difference attributable to restriction in choline content (from 5.3 g/kg to 0.3 g/kg) at a fixed protein content; by 1-way ANOVA with Tukey’s post hoc testing.…”

Electric field-navigated transcranial magnetic stimulation for chronic tinnitus: a randomized, placebo-controlled study by Hanna Sahlsten (3930824)

“…<i>Study sample:</i> Thirty-nine patients (mean age 50.3 years). <i>Results</i>: The mean tinnitus intensity (<i>F</i>₃ = 15.7, <i>p</i> < 0.0001), annoyance (<i>F</i>₃ = 8.8, <i>p</i> = 0.0002), distress (<i>F</i>₃ = 9.1, <i>p</i> = 0.0002) and THI scores (<i>F</i>₄ = 13.8, <i>p</i> < 0.0001) decreased in both groups over time with non-significant differences between the groups. …”

MicroRNA regulation of cellular mRNAs during influenza virus infection. by William A. Buggele (463461)

“…<div><p>(A) A549 cells were mock infected, infected with A/WSN/33 (5 pfu/cell), or infected after transfection with an equimolar mixture of miRNAs (50nM final concentration) that included either hsa-miR-141, hsa-miR-374b, hsa-miR-449b, hsa-miR-518b, and hsa-miR-1263 (G1), or hsa-miR-147b, hsa-miR-190b, hsa-miR-199a-5p, hsa-miR-512-5p, and hsa-miR-874 (G2). …”

The effect of rapamycin on gene expression in hepatic cells. by Rosa H. Jimenez (253441)

“…<p>Cells were exposed to DMSO vehicle (V) or rapamycin (R; 50 nM) for 24 hr. RNA was prepared and analyzed by microarray using Affymetrix GeneChip® Rat Genome 230 2.0 Array for the WB-F344 and WB311 cells, or RatRef-12 Whole Genome Expression BeadChips for the GN5 and H5D cells. …”

Fitness reaction norms and experimental evolution design. by Thiago S. Guzella (5920229)

“…Crossing of fitness reaction norms means that genotypes will be favored at some environmental values while disfavored in others. …”

Image4_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image6_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image3_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Table2_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.DOCX by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image1_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Table4_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.docx by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image2_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image7_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Table3_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.docx by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”