Impaired fibronectin and fibrinogen-cleaving activities of the E143A and H146A Zmp1 mutants. by Valeria Cafardi (490077)

“…(<b>C</b>) Decreased ability of E143A and H146A Zmp1 mutants to cleave fibronectin. 1 µM fibronectin from human plasma was incubated for 24 h at 37°C with no Zmp1 (control) or with 7.7 µM of wild type (WT), E143A or H146A Zmp1 in the presence of 0.5 mM ZnCl₂. 1 µg of fibronectin was analyzed by SDS-PAGE and Coomassie-blue staining. …”

FIGURE 5 from Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor by Shruti Lal (16805936)

“…<p>Phosphoproteomic screen identifies MCM2 Ser108 phosphorylation decreased by ZL-2201. <b>A,</b> Simple Western showing inhibition of pDNA-PK upon treatment with PRKDC siRNA, 300 nmol/L and 3.5 μmol/L of ZL-2201 ± 10 μmol/L bleomycin used in phospho-MS screen analysis. …”

<i>Trem1^−/−</i> mice develop smaller inflammatory lesions and show decreased cellular infiltrates at <i>L. major</i> infection sites. by Benjamin Weber (509906)

Decreased NK1.1^pos iNKT cell numbers in the peripheral organs of T cell-specific <i>Gfi1</i>-deficient mice. by Toshiaki Yasuoka (2827457)

Underlying data for Figs 6, S5, and S6. by Kun Wu (286745)

Image_5_GPR174 mRNA Acts as a Novel Prognostic Biomarker for Patients With Sepsis via Regulating the Inflammatory Response.tif by Jianli Wang (1305390)

Image 5_Age- and sex-specific reference intervals for trace elements in infants and children: a multi-center study in Lincang, China.jpg by Junqiang Li (491954)

Data_Sheet_1_Mental health across two years of the COVID-19 pandemic: a 5-wave longitudinal study in Germany.PDF by Maxi Weber (12420430)

Table 5_Dynamic proteomics reveals that endosperm weakening plays a critical role during seed germination in Polygonatum cyrtonema Hua.xlsx by Huilong Xu (1358961)

In Vitro Screening for ToxCast Chemicals Binding to Thyroxine-Binding Globulin by Stephanie A. Eytcheson (4284421)

“…Initial screening at a single high concentration of 100 μM identified 714 chemicals that decreased signal of the bound fluorescent ligand by 20% or higher. …”

PEDV and PDCoV infection impairs the cilium. by Tenghan Zhuang (22238809)

“…Notably, infection by either porcine epidemic diarrhea virus (PEDV) or porcine deltacoronavirus (PDCoV) resulted in a significant decrease in both the percentage of cells with cilium and the average ciliary length across all three porcine cell lines (<i>C-D, F-G, and I-J</i>). …”

Table_5_The Effect of Dexmedetomidine on Emergence Agitation or Delirium in Children After Anesthesia—A Systematic Review and Meta-Analysis of Clinical Studies.DOC by Yuquan Rao (9118304)

Video_5_Programmable Attenuation of Antigenic Sensitivity for a Nanobody-Based EGFR Chimeric Antigen Receptor Through Hinge Domain Truncation.avi by Scott McComb (234597)

Image5_Pan-cancer analysis of the prognosis and immunological role of AKAP12: A potential biomarker for resistance to anti-VEGF inhibitors.tif by Qiuju Liang (588501)

<strong>Figure 1.</strong> <strong>Actin filament depolymerization has no effect on the decrease in the cytosolic ATP level induced by blockade of ATP production in forebrain neuro... by Sabrina Holland (16557051)

Label-Free Proteomics Reveals Decreased Expression of CD18 and AKNA in Peripheral CD4⁺ T Cells from Patients with Vogt-Koyanagi-Harada Syndrome by Liming Mao (231467)

“…The results revealed that the expression of 102 peptides was significantly altered (p<0.05) between two groups and matched amino acid sequences of proteins deposited in the international protein index (ipi.HUMAN.v3.36.fasta). The identified peptides corresponded to 64 proteins, in which 30 showed more than a 1.5-fold difference between the two groups. …”

Table1_Diacerein reduces inflammasome activation and SARS-CoV-2 virus replication: a proof-of-concept translational study.xlsx by Helison R. P. Carmo (19810212)

“…Diacerein has emerged as a potential therapy for COVID-19 due to its potential impact in decreasing the inflammasome activation and coronavirus replication. …”

Image_5_Male and female are not the same: a multicenter study of static and dynamic functional connectivity in relapse-remitting multiple sclerosis in China.jpeg by Yao Wang (102387)

Image_5_Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses.jpeg by Giulia Monticone (13431972)

Data_Sheet_5_Construction and Analysis of a ceRNA Network in Cardiac Fibroblast During Fibrosis Based on in vivo and in vitro Data.PDF by Qing-Yuan Gao (10013927)

“…Finally, two mRNA [ADAM metallopeptidase domain 19, (ADAM19) and transforming growth factor beta induced, (TGFBI)], three microRNA (miR-9-5p, miR-124-3p, and miR-153-3p) and two lncRNA (LINC00511 and SNHG15) constituted our ceRNA network. siRNA against LINC00511 increased miR-124-3p and miR-9-5p expression, and decreased ADAM19 and TGFBI expression, whereas siRNA against SNHG15 increased miR-153-3p and decreased ADAM19 expression. …”