Data_Sheet_4_Telomere length and the risk of cardiovascular diseases: A Mendelian randomization study.PDF by Yingjian Deng (13999767)

“…</p>Materials and methods<p>In this two-sample MR study, we identified 154 independent TL-associated genetic variants from a genome-wide association study (GWAS) consisting of 472,174 individuals (aged 40–69) in the UK Biobank. …”

DataSheet_1_Post-anthesis supplementary irrigation improves grain yield and nutritional quality of drip-irrigated rice (Oryza sativa L.).docx by Xiangbin Wang (175667)

“…Introduction<p>Approximately 50% of irrigation water is saved during drip-irrigation of rice, which has tremendous potential for water-saving agriculture, particularly in areas where water resources are scarce. …”

DataSheet_1_Age-Related Changes of Peak Width Skeletonized Mean Diffusivity (PSMD) Across the Adult Lifespan: A Multi-Cohort Study.pdf by Grégory Beaudet (8795096)

“…RD, MD, and AD variations with age exhibited the same U-shape pattern, first slowly decreasing during post-adolescence until the age of 30, 40, and 50 years, respectively, then progressively increasing until late life. …”

Data_Sheet_6_Telomere length and the risk of cardiovascular diseases: A Mendelian randomization study.PDF by Yingjian Deng (13999767)

“…</p>Materials and methods<p>In this two-sample MR study, we identified 154 independent TL-associated genetic variants from a genome-wide association study (GWAS) consisting of 472,174 individuals (aged 40–69) in the UK Biobank. …”

Data_Sheet_3_Telomere length and the risk of cardiovascular diseases: A Mendelian randomization study.PDF by Yingjian Deng (13999767)

“…</p>Materials and methods<p>In this two-sample MR study, we identified 154 independent TL-associated genetic variants from a genome-wide association study (GWAS) consisting of 472,174 individuals (aged 40–69) in the UK Biobank. …”

Table_1_Burden of liver cancer due to hepatitis C from 1990 to 2019 at the global, regional, and national levels.docx by Jie Wei (264772)

“…From 1990 to 2019, the number of incidences, mortality, and DALY cases increased by 80.68%, 67.50%, and 37.20%, respectively. However, the age-standardized incidence, mortality, and DALY rate had a decreasing trend during this period. …”

<i>Igf-1r</i> hemizygosity has minimal effect on the levels of mutant huntingtin protein. by Silvia Corrochano (618848)

“…Scale bar represents 50 µm. <b>E</b>. Automated quantification of images from D according to aggregate size reveal an increase in the percentage of small-size aggregates (0–0.3 µm²) coupled with a decreased in the percentage of medium-sized aggregates (0.3–0.9 µm²) in HD; <i>Igf-1r^+/−</i> cerebellum compared to controls (p<0.001). …”

Table_1_Telomere length and the risk of cardiovascular diseases: A Mendelian randomization study.xlsx by Yingjian Deng (13999767)

“…</p>Materials and methods<p>In this two-sample MR study, we identified 154 independent TL-associated genetic variants from a genome-wide association study (GWAS) consisting of 472,174 individuals (aged 40–69) in the UK Biobank. …”

Age-related changes in bone architecture by VINCENZO GIORDANO (5378453)

'Do Anthracyclines Elevate Intracellular Oxidative Stress?' by Anthony Purcell by Anthony Purcell (11008607)

Gem-Induced Cytoskeleton Remodeling Increases Cellular Migration of HTLV-1-Infected Cells, Formation of Infected-to-Target T-Cell Conjugates and Viral Transmission by Sébastien A. Chevalier (149797)

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder by Comfort A. Boateng (3617120)

“…Novel analogue <b>16f</b> is a potent low-efficacy D₄R partial agonist, metabolically stable in rat and human liver microsomes, and has excellent brain penetration in rats (AUC_brain/plasma > 3). <b>16f</b> (5–30 mg/kg, i.p.) dose-dependently decreased iv cocaine self-administration in rats, consistent with previous results produced by D₄R-selective antagonists. …”

DataSheet_1_Risk Factors for Brain Metastases in Patients With Small Cell Lung Cancer: A Systematic Review and Meta-Analysis.docx by Haiyan Zeng (3753130)

“…Eligibility criteria: studies reporting detailed BM data with an adequate sample size (randomized clinical trials [RCTs]: N ≥50; non-RCTs: N ≥100) in patients with SCLC. We summarized the reported risk factors and performed meta-analysis to estimate the pooled hazard ratios (HR) if enough qualified data (i.e., two or more studies; the same study type; the same analysis method; and HRs retrievable) were available. …”

Table 1_The impact of comorbidities on surgical outcome and mortality in minimally invasive mitral valve surgery: a systematic review.docx by Vanessa I. T. Zwaans (22163257)

“…Left atrial (LA) diameter decreased significantly from 50.37 mm preoperatively to 40.41%mm postoperatively (p < 0.001), LVDD was significantly reduced after MIMVS (p < 0.001). …”