Bevacizumab prevented hyperglycaemia-mediated neurite outgrowth impairment and normalized FLT-1. by Michela M. Taiana (636319)

“…<p>(A) bevacizumab prevented the decrease of hyperglycaemia-mediated neurite outgrowth in neuron-SC co-cultures (<i>n</i> = 5) and (B) the increase of FLT-1 mRNA in neurons monocultures (<i>n</i> = 5). …”

Length Scale of the Dendritic Array Tailoring Strength of a 5052 Aluminum Alloy by Cínthia Toshimi Ogata (6046400)

“…<div><p>The present research aims to characterize 5xxx alloy series, considering chemistries based on the commercial 5052 alloy with three Mg contents (2.4wt.%, 2.6wt.% and 3.2wt.%) through transient directional solidification experiments. …”

Snail1 loss altered cytoskeletal organization and gene expressions in RMG1 cells. by Misako Haraguchi (768459)

“…Snail1 KO1 cells showed a complete loss of Snail1 expression and an increase in E-cadherin, occludin and claudin-1, beta-actin, alpha- tubulin, as well as a decreased in integrin alpha 5 expression. Transient expression of Snail1 in Snail1 KO cells reversed these effects, except for the decreased in integrin alpha 5 expression. …”

Tuning of Msn2 expression in rapidly growing cells. by Michal Chapal (7961111)

“…Shown are the median of all strains and repeats in solid line and 25th–75th percentiles in the shaded areas. Dashed lines indicate WT Msn2 level. (F–G) Noisy Msn2 expression decreases stress protection and growth rate: we generated six strains with Msn2-YFP expressed under different promoters, which control genes with noisier expression than Msn2 but have a similar mean abundance (mean abundance in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000289#pbio.3000289.s005" target="_blank">S5 Fig</a>), and deletion of <i>MSN4</i>. …”

A Reduce and Replace Strategy for Suppressing Vector-Borne Diseases: Insights from a Stochastic, Spatial Model by Kenichi W. Okamoto (500514)

“…We find this “reduce and replace” strategy can decrease the frequency of competent vectors below 50% two years after releases end. …”

Obesity and leptin resistance in <i>Bbs4^−/−</i> mice are rescued by <i>LAP-BBS4</i>. by Xitiz Chamling (390467)

“…<i>Bbs4^tg</i> mice (blue line) are not significantly heavier than WT mice (green line) at any age. Data are presented as mean +/− SEM, n = 10 per genotype. …”

CStS recapitulate MSNs degeneration observed in R6/2 mouse model. by Catia C. Proenca (431486)

“…Neurodegeneration is observed as a decrease in marker intensity. F) Left: quantification for the ratio of striatal NeuN and DAPI positive nuclei in WT and R6/2 slices at DIV21. …”

Ionizing radiation–induced DSBs and repair. by Jim Westmoreland (260234)

“…<p>Haploid cells growing logarithmically in YPDA media were arrested at G2/M with nocodazole and γ-irradiated with 5 to 80 krads from a Cs source. Cells from the 80 krad dose were returned to YPDA containing nocadazole and incubated for up to 4 hours to allow repair of DSBs (A) DSBs and repair in WT and <i>exo1Δ</i> strains. …”

ROP18 directly phosphorylates Irga6 at T102 and T108 in vitro. by Tobias Steinfeldt (154465)

“…The autoradiogram reveals efficient phosphorylation of wt Irga6 and a decrease in signal intensity for all Irga6 alanine mutants. …”

Effects of Shenfu injection on shivering prevention and hemodynamic impact in elderly patients underwent transurethral resection of the prostate by Weiqi KE (10464517)

“…Compared to the control group, patients in the experiment group had significantly less decrease in temperature (36.02 ± 0.29 °C in the experiment group versus 35.50 ± 0.33 °C in the control group, p = 0.047). …”

A Reappraisal of the Mechanism by Which Plant Sterols Promote Neutral Sterol Loss in Mice by Gemma Brufau (215229)

“…PS feeding resulted in a dose-dependent decrease of fractional cholesterol absorption (∼2–7-fold reduction) in wild-type mice and ∼80% reduction in Abcg5^-/- mice. …”

Developmental changes in DKO mice. by Lindsay Wieczorek (171734)

“…<p>Two genes identified with microarray analysis and showing the most significant change between WT and DKO mice, (<b>A</b>) Slc11a2 (n = 5, *p≤0.0001), with a −1.3 fold change, and (<b>B</b>) Lynx1 (n = 5, *p≤0.0001), with −1.4 fold change, were confirmed via RT-PCR. …”

Influence of MgCl and ATP on primer unblocking by AZT-resistant RT by Valérie Goldschmidt (13343)

“…All rights reserved</p> () ssDNA synthesis was performed in the presence of 3.5 mM ATP and 4 µM AZTTP with wt or AZT-resistant RT at 2 or 6 mM MgCl. …”

Inspiratory muscle training is effective to reduce postoperative pulmonary complications and length of hospital stay: a systematic review and meta-analysis by Filipa Kendall (3642886)

“…IMT significantly reduced the risk of PPC (Risk Ratio (RR) = 0.50, 95%CI: 0.39, 0.64, <i>I²</i>=<i></i>0.0%), and a decrease in LOS (Mean Difference = −1.41, 95%CI: −2.07, −0.75, <i>I</i>² = 0.0%).…”

Compromised Purkinje cell dendritic arborization, reduction in glutamatergic synapses and ultrastructural alterations in the cerebellar cortex of <i>atc/atc</i> mice. by Maria Eirini Terzenidou (3903223)

“…<b>(G)</b> Immunostaining of sagittal cerebellar sections from 4 week-old mice reveals a significant decrease in the expression of vGlut1 both in PC-parallel fiber synapses in the ML as well as in granule cell-mossy fiber synapses in the IGL of the cerebellar cortex of <i>atc/atc</i> mice. …”

TOP1α and UPF1 directly repress <i>TTG2</i>. by Chengxiang Li (5278343)

“…Expression values normalized against <i>U-BOX</i> are shown relative to the expression level in WT. Values are mean ± s.d. of three biological replicates. …”

The increased myeloid priming of Id1 null HSCs requires the expression of p21 by Alessia Ciarrocchi (37383)

“…Numbers indicate average colony numbers±SEM (WT 1.5±0.64 n = 4; Id1-/- 3.8±0.58 n = 5; Id1-/-p21-/- 0.5±0.28 n = 4; p21-/- 1±0.40 n = 4) D) Quantitative real time PCR analysis of c/EBPα mRNA levels in sorted HSCs. …”

Hypothetical scheme of the stress response in the brain. by Olena Babenko (186646)

VEGFR1 and VEGFR2 Involvement in Extracellular Galectin-1- and Galectin-3-Induced Angiogenesis by Nicky D'Haene (422477)

DataSheet_1_Irrigation with primary wastewater alters wood anatomy and composition in willow Salix miyabeana SX67.docx by Ahmed Jerbi (14708509)

“…The majority (86%) of vessels had diameters range groups [20-30[, [30-40[and [40-50[µm and contributed to > 75% of theoretical K_S, while the group class [50-60[µm (less than 10% of vessels) still accounted for > 20% of total K_S regardless irrigation treatments. …”