Ca²⁺ binding mutants had differential effects on evoked and spontaneous release. by Mallory C. Shields (4474210)

“…Scale bars = 5 mV, 0.1 s. <b>B</b>. Mean EJP amplitude in <i>P[syt^D-N]</i> was unimpaired, but in <i>P[syt^D-E]</i>, it was significantly decreased compared to control (*p < 0.0001). …”

Oxygen uptake kinetics and energy system’s contribution around maximal lactate steady state swimming intensity by Jailton Gregório Pelarigo (3801085)

“…Subjects showed similar time delay (TD) (mean = 11.5–14.3 s) and time constant (τ_p) (mean = 13.8–16.3 s) as a function of v, but reduced amplitude of the primary component for 97.5% (35.7 ± 7.3 mL.kg.min^-1) compared to 100 and 102.5%MLSS (41.0 ± 7.0 and 41.3 ± 5.4 mL.kg.min^-1, respectively), and τ_p decreased (mean = 9.6–10.8 s) during the second phase of exercise. …”

Loss of the macrophage-TCR in the presence of functional T cells results in disorganized granulomas and CCL2 suppression in murine pulmonary tuberculosis. by Alexander W. Beham (196299)

“…Chimeric tnf^–/–(T cell wt) mice with systemic deletion of TNF but wildtype T cells display disorganized granulomas characterized by absence of CCL2 (v, vi) similarly as observed in macrophage-TCR deficient mice (iii, iv). …”

The role of HBP1 and Wnt signaling in acquired seizure susceptibility. by Roaya S. Alqurashi (11243136)

“…(n = 3–5 mice for each group). Data are represented as mean ± SEM. …”

Modulation of AChR and GABA_R can restore post-synaptic folding. by M. Catarina Silva (189975)

“…(F) Real-time qPCR analysis of <i>hsp-70</i> (<i>C12C8.1, F44E5.4</i>) levels in 5 day old wt animals upon treatment with ACh, levamisole or the GABA_R antagonist Lindane, or upon decrease in GABAergic signaling by either RNAi or mutant backgrounds of <i>unc-47(gk192)</i>, <i>unc-49(e407)</i> or <i>unc-30(e191)</i>. …”

The power for detecting association with secondary traits in selected samples. by Dajiang J. Liu (120143)

“….), where 80% of the causal variants increase the mean secondary trait value and the other 20% decrease the mean secondary trait value. …”

Proteasome inhibition decouples infectious DENV2 production from viral RNA replication in THP-1 cells. by Milly M. Choy (790882)

“…(D) Proteasome inhibition showed a dose-dependent decrease in plaque titers 48 hpi. Mean ± SD. N = 4. …”

Effect of Glucose Concentration on Life Span and Sir2 Activity in Respiratory-Deficient Mutants by Matt Kaeberlein (12437)

“…<div><p>(A) Mean replicative life span is significantly increased in PSY316 AUT <i>cyt1</i>Δ and rho⁰ cells as the glucose concentration is decreased to either 0.5% or 0.05%, relative to life span on 2% glucose. …”

Deletion of <i>hfq</i> impacts central metabolism. by Irnov Irnov (282410)

“…<p>(A) Heatmap showing the changes in the level of various metabolites among the WT, Δ<i>hfq</i>, Δ<i>hfq vor</i>::Tn<i>5</i>, and <i>vor</i>::Tn<i>5</i> strains, as measured by LC-MS. …”

Supporting main Fig 4. by Jyoti Tanwar (2230597)

“…(C) qRT-PCR analysis showing decrease in keratin 5 mRNA expression upon keratin 5 silencing in B16 cells (<i>N</i> = 3). …”

Figure S1 - Electrical Stimuli Are Anti-Apoptotic in Skeletal Muscle via Extracellular ATP. Alteration of This Signal in Mdx Mice Is a Likely Cause of Dystrophy by Denisse Valladares (489234)

“…</b> Normal and dystrophic muscle fibers were stimulated with different concentrations of external ATP and mRNA levels of Bax were measured 1 h after ATP addition (A and C). We observed the maximum decrease in mRNA levels when using a concentration of 100 µM in normal fibers (A), while the maximum values were found for 50 and 100 µM in dystrophic fibers (B) (n = 4). …”

Temporal Trends in Exposures to Six Phthalates from Biomonitoring Data: Implications for Cumulative Risk by Jeanette M. Reyes (1306353)

“…Over this period, there was a 2.2-fold decrease in the mean HI (0.34 to 0.15) and a 7.2-fold decrease in the percentage of participants with an HI > 1 (5.7% to 0.8%), indicating an overall decrease in combined exposure to these phthalates. …”

SREBP-1 is dispensable but not required for neuritogenic effect of SIM. by Varshiesh Raina (457377)

“…SIM led no change on SREBP-1 cleavage except that a significant (<i>p</i> < 0.05^*) decrease was observed at 2 hrs. Error bar graph represents the fold change (normalized to actin) in p68 protein form at different time points in presence of SIM (mean ± SEM; n = 3). …”

Mast cell density and ano-genital sensitivity following therapeutic imatinib treatment in ND4 female mice previously exposed to MI. by Jaclyn M. Kline (9565161)

“…(C) Quantification of avidin⁺ mast cell density in 10 μm labiar skin cryo-sections collected 1 day after 6 daily therapeutic Imatinib treatments or NT following 10 daily MI treatments in previously sensitized mice. Results displayed as mean ± SEM, n = 5-6/treatment group, representing 2 experiments. …”

Epidemiology of sepsis in Brazil: Incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015 by Ricardo Alfredo Quintano Neira (5100806)

“…</p><p>Results</p><p>From 2006 to 2015, the annual sepsis incidence increased 50.5% from 31.5/100,000 to 47.4/100,000 persons. …”

Water temperature affects aggressive interactions in a Neotropical cichlid fish by Manuela L. Brandão (5021027)

Does total testicular volume predict testicular volume difference in adolescent males with varicocele? by Ari P. Bernstein (5912306)

“…Results: 209 patients met our inclusion criteria. Mean age was 18.3 years (16–21, SD 1.7) with a mean total testicular volume of 36 cc (13.5-78.2, SD 11.1). …”

Mef2C is regulated during neurogenesis, in turn contributing to miR-9 induction. by Jonathan L. Davila (548756)

“…(C) Deletion of Mef2 binding sites in the upstream regulatory region diminishes transcription activity of the miR-9-2 gene locus. A 5 kb upstream sequence of the rat miR-9-2 gene was cloned into the promoter-less pGL4.10 luciferase reporter vector (wild-type, WT). …”

Influence of nitrogen doping on the electrocatalytic activity of Ni-incorporated carbon nanofibers toward urea oxidation by Barakat, Nasser A.M.

“…However, the electrochemical measurements indicated that the content of the urea in the initial electrospun solution should be optimized as the results showed that the best nickel surface activation as well as the maximum observed current density can be achieved when the urea content is kept at 5 wt%. Typically, the observed current densities using 1.0 M urea (in 1 M KOH) were 3.15, 29.7, 13.75, 47.55, 14.13 and 9.85 mA/cm2 for the nanofibers obtained from electrospun solutions having 0, 1, 2, 5, 7 and 9 wt% urea, respectively. …”
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Controls for fitness experiments and Phosphosite Scanning. by Michelle M. Conti (13514386)

“…Plasmid expressed copies of Hcm1 are tagged with V5 and were expressed throughout the experiment. …”