Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma by Zhihao Liu (419349)

“…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …”

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma by Zhihao Liu (419349)

“…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …”

Image_1_Reduced Ca2+ transient amplitudes may signify increased or decreased depolarization depending on the neuromodulatory signaling pathway.PDF by Arunima Debnath (13136676)

Mesothelin expression and RG7787 uptake is decreased in KLM-1-R. by Kevin Hollevoet (710450)

Data from: Spillage and food dust do not decrease efficacy of long-lasting insecticide-incorporated netting against stored product insects by Sabita Ranabhat (17484660)

Thalidomide treatment inhibits growth in RAMEC but not in RAMEC transfected with a dominant negative mutant of CUL5 (^S730ACUL5) cDNA. by Bryan Kunkler (5204327)

Predicted cylindrical cavity pressure as a function of saturation for two clay contents (16 and 50%) and for a range of cavity radii (1 to 5 mm). by Siul Ruiz (757454)

NRX-1 localization to cholinergic axons is decreased in <i>unc-104</i> mutants and colocalizes with UNC-104 in cholinergic axon terminals. by Devyn Oliver (12015660)

Gender differences in what subjects students report they might find offensive if an instructor of a college science course were to tell a joke about them. by Katelyn M. Cooper (5634851)

Gender differences in what subjects students report they might find funny if an instructor of a college science course were to tell a joke about them. by Katelyn M. Cooper (5634851)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Low-dose <b>35m</b> remarkably decreases LPS-induced IL-1β release both <i>in vitro</i> and <i>in vivo</i> by blocking the activation of NLRP3, indicating that <b>35m</b> can be a potential orally active therapeutic agent for the treatment of NLRP3-related diseases.…”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Low-dose <b>35m</b> remarkably decreases LPS-induced IL-1β release both <i>in vitro</i> and <i>in vivo</i> by blocking the activation of NLRP3, indicating that <b>35m</b> can be a potential orally active therapeutic agent for the treatment of NLRP3-related diseases.…”

Dynamics of a Stick−Jump Contact Line of Water Drops on a Strip Surface by Xueyun Zhang (507745)

“…In this study, we prepared microscale periodic rough structures consisting of parallel strips on a silicon surface. …”

DataSheet1_Solamargine Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma by Decreasing LncRNA HOXA11-As Expression.PDF by Ying Meng (327793)

<i>H</i>. <i>diminuta</i> and <i>T</i>. <i>muris</i> antigens decrease acidification in Mtb infected macrophages. by Naomi Aira (3743911)

Supplementary Material for: Inverse and Direct Cancer Comorbidity in People with Central Nervous System Disorders: A Meta-Analysis of Cancer Incidence in 577,013 Participants of 50... by Catalá-López F. (4142920)

“…<b><i>Method:</i></b> Comprehensive search in PubMed/MEDLINE, Scopus and ISI Web of Knowledge of the literature published before March 2013. We identified 51 relevant articles from 2,229 discrete references, 50 of which contained data suitable for quantitative synthesis (577,013 participants). …”

rAd-p53 induces apoptosis in HCC cell lines with increased Fbxw7 and decreased c-Myc and Cyclin E. by Kangsheng Tu (428934)

“…<p>A) MTT activity was measured after infecting Hep3B cells with rAd-p53 in an MOI gradient to determine their IC₅₀ after 48 h. …”

Decreased s.c. growth of CNDT 2.5 cells after systemic administration of DOPC liposome-conjugated siNRP-2. by Shaija Samuel (341436)

Multinomial logistic model of the effects of a cluster of phenolic compounds on host and parasitoid survival across development among larvae that survived to at least 50 mg. by Noah H. Rose (703745)

Antagonism of ghrelin receptors resulted in decreased reward and delayed reductions of EtOH-motivated behaviors with an overall increased sensitivity in RYGB rats. by Andras Hajnal (299955)