Suitability of Porcine Chondrocyte Micromass Culture To Model Osteoarthritis in Vitro by Niels Schlichting (1783198)

“…The limited availability of human primary tissue and high costs of animal models hamper preclinical tests of innovative substances and techniques. In this study we tested the potential of porcine chondrocyte micromass cultures to mimic human articular cartilage and essential aspects of osteoarthritis (OA) in vitro. …”

Table1_Epstein-Barr virus-specific T-cell response in pediatric liver transplant recipients: a cross-sectional study by multiparametric flow cytometry.docx by Ricardo Cuesta-Martín de la Cámara (15407492)

“…Background<p>Epstein-Barr virus (EBV) specific T-cell response measurement can help adjust immunosuppression in transplant patients with persistent infections. We aim to define T-cell responses against EBV in a cohort of pediatric liver-transplant patients.…”

Image_3_Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis.tif by H. Mark Kenney (10320665)

“…Integration of single-cell and spatial transcriptomics revealed the increased IgG2b⁺ plasma cells localized in MARCO⁺ peri-follicular medullary sinuses. A concomitant decreased Fth1 expression (Early 2.5 ± 0.74 vs Advanced 1.0 ± 0.50 counts, p<0.001) within Advanced PLN sinuses was associated with accumulation of iron-laden Prussian blue positive macrophages in lymph nodes and synovium of Advanced TNF-Tg mice, and further validated in RA clinical samples. …”

Space-based scanpath model design. by Nicolas Roth (11568286)

“…The frame-wise saliency maps are multiplied with a generic center bias [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011512#pcbi.1011512.ref059" target="_blank">59</a>]. …”

DataSheet_1_Hyperthyroidism Prevalence in China After Universal Salt Iodization.docx by Chuyuan Wang (10889535)

“…OH and GD prevalence were higher in women than in men (OH: 1.16% vs. 0.64%, P<0.001; GD: 0.65% vs. 0.37%, P<0.001).Prevalence was significantly decreased after 60 years-of-age compared with 30–39 years-of-age (OH:0.61% vs. 0.81%, P<0.001; GD: 0.38% vs. 0.57%, P<0.001).Excessive iodine(EI) and deficient iodine(DI) were both related to increased prevalence of OH (odds ratio [OR] 2.09, 95% confidence interval [CI] 1.68–2.59; OR1.35, 95%CI 1.07–1.72, respectively); however, only deficient iodine was associated with increased prevalence of GD (OR1.67, 95%CI 1.30–2.15). …”

Supplementary file 1_Persistent burden and health inequalities of disease in women of childbearing age attributable to Intimate Partner Violence, 1990–2021.docx by Yingda Song (15410321)

“…The absolute value of the SII for ASMR increased from 2.04 in 1990 to 4.59 in 2021, while that of the SII for ASDR decreased from 321 in 1990 to 190 in 2021. …”

The effects of sympathetic activity induced by ice water on blood flow and brachial artery flow-mediated dilatation response in healthy volunteers by Kristian Magnus Gundersen (7382027)

“…Measurements were taken at baseline; before a 5-min suprasystolic forearm occlusion; and following a 3-min post-occlusion, to measure reactive hyperemia and FMD.…”

DataSheet_1_Large-scale genome-wide association study to identify causal relationships and potential mediators between education and autoimmune diseases.docx by Yingjie Li (2106778)

“…Higher levels of educational attainment decreased risks of psoriasis (OR = 0.61, 95% CI = 0.52-0.72, p = 1.12×10^-9), RA (OR = 0.68, 95% CI = 0.59-0.79, p = 1.56×10^-7), and hypothyroidism (OR = 0.80, 95% CI = 0.72-0.88, p = 5.00×10^-6). …”

DataSheet_2_Large-scale genome-wide association study to identify causal relationships and potential mediators between education and autoimmune diseases.xlsx by Yingjie Li (2106778)

“…Higher levels of educational attainment decreased risks of psoriasis (OR = 0.61, 95% CI = 0.52-0.72, p = 1.12×10^-9), RA (OR = 0.68, 95% CI = 0.59-0.79, p = 1.56×10^-7), and hypothyroidism (OR = 0.80, 95% CI = 0.72-0.88, p = 5.00×10^-6). …”

Effects of exercise on circulating tumor cells among patients with resected stage I-III colon cancer by Justin C. Brown (185942)

“…Over six months, significant decreases in CTCs were observed in the low-dose (−1.34±0.34; <i>P</i><0.001) and high-dose (−1.18±0.40; <i>P</i> = 0.004) exercise groups, whereas no significant change was observed in the control group (−0.59±0.56; <i>P</i> = 0.292). …”

Postoperative complications and mortality [n(%)]. by Qingwen Cao (22439195)

“…There was a higher proportion of femoral neck fractures in the YO group and a higher incidence of intertrochanteric fracture in the OO group (<i><i>P</i> <i><</i></i> 0.001). …”

Information of surgery and anesthesia [n(%)]. by Qingwen Cao (22439195)

“…There was a higher proportion of femoral neck fractures in the YO group and a higher incidence of intertrochanteric fracture in the OO group (<i><i>P</i> <i><</i></i> 0.001). …”

Raw data. by Qingwen Cao (22439195)

“…There was a higher proportion of femoral neck fractures in the YO group and a higher incidence of intertrochanteric fracture in the OO group (<i><i>P</i> <i><</i></i> 0.001). …”

Relationship between YAP N/C ratio and cell spreading states of single B2B cells on 2-kPa hydrogels substrates. by Qin Luo (2182514)

“…<p>(<b>A</b>) 3D fluorescent confocal YAP image stack of a single spreading B2B cell on 2-kPa substrate at 0.5^th, 5^th, and 10^th hour. …”

DataSheet1_Quantifying the impact of novel metastatic cancer therapies on health inequalities in survival outcomes.pdf by Karolina Zebrowska (17444970)

“…In terms of PFS, the increases in survival inequalities were larger in a relative sense compared with OS. For mBC, PFS inequalities increased by 8.7 (5.9; 11.6) months, or 71.7%, for stratification based on 5 groups; the IG increased by 2.0 (1.3; 2.6) months, or 67.6%. …”

Data_Sheet_1_Association of maternal education, neighborhood deprivation, and racial segregation with gestational age at birth by maternal race/ethnicity and United States Census r... by Anne L. Dunlop (4682503)

“…Those with a high school diploma or less also had an increased odds of preterm (aOR 1.59, 95% CI: 1.20, 2.10) and early term birth (aOR 1.26, 95% CI: 1.05, 1.51). …”

Reduced control model M2: Only oscillation of the likelihood. by Veith Weilnhammer (2909060)

“…<p>When simulating data for the <i>likelihood-oscillation-only model</i>, we removed the oscillation from the prior term by setting the amplitude <i>a</i>_<i>ψ</i> to 0. …”

Lack of CHOP protein does not protect T17M <b><i>RHO</i></b><b> retinas from degeneration, as measured by scotopic ERG responses at 10DB.</b> by Sonali Nashine (408442)

“…<p>We analyzed 4 groups of animals (N = 6). A: The a-wave of the scotopic ERG amplitude was diminished in T17M <i>RHO</i> CHOP−/− mice at 1 month of age and the values of a-wave amplitudes were 456.3 µv ±39.7 in wild-type; 509.1 µv ±24.9 in CHOP−/−; 169.0 µv ±7.9 in T17M <i>RHO</i>; and 54.4 µv ±16.4 in T17M <i>RHO</i> CHOP−/−. …”

Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: Systematic review and meta-analysis by Oonagh E. Keag (4789215)

“…Children delivered by cesarean delivery had increased risk of asthma up to the age of 12 years (OR 1.21, 1.11 to 1.32; <i>n</i> = 887,960; 13 studies) and obesity up to the age of 5 years (OR 1.59, 1.33 to 1.90; <i>n</i> = 64,113; 6 studies). …”

H2AK119ub is depleted from facultative heterochromatin as the cerebellum matures. by Aditya Parmar (22331873)

“…<b>(C)</b> Heatmaps depicting H2AK119ub CUT&RUN data in the early and late cerebellum centered around H3K27me3 peak summits identified by MACS2 [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref059" target="_blank">59</a>] narrow in the early cerebellum. …”