Lipid droplets transiently increase in size during early stages of HSV-1 infection. by Kamal L. Nahas (13014698)

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…Moreover, the compound dose-dependently decreases β-site amyloid precursor protein cleaving enzyme (BACE-1) activity with EC₅₀ value in micromolar range. …”

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…Moreover, the compound dose-dependently decreases β-site amyloid precursor protein cleaving enzyme (BACE-1) activity with EC₅₀ value in micromolar range. …”

E1784K accelerates a component of slow inactivation with 1-10s time constants. by Colin H. Peters (4430245)

“…<p><b>(A1 and A2)</b> Sample inward sodium currents recorded after 20ms to 60s repolarization pulses to -90mV following either a 500ms or 64s depolarization to -30mV. …”

Venn diagram of co-expression of CrBV genes (A) and cluster heatmaps of gene expression levels in parasitized FAW (B). by Xian Li (201841)

Table_1_Decreased Vessel Density in Retinal Capillary Plexus and Thinner Ganglion Cell Complex Associated With Cognitive Impairment.DOCX by Kai Yang (73590)

Image_1_Decreased Vessel Density in Retinal Capillary Plexus and Thinner Ganglion Cell Complex Associated With Cognitive Impairment.TIF by Kai Yang (73590)

<i>In vitro</i> activity of aryl-thiazole derivatives against <i>Schistosoma mansoni</i> schistosomula and adult worms by Adriana S. A. Pereira (5900249)

“…After <i>in vitro</i> treatment for five days with 6.25 μM NJ05 or NJ07 separately, we observed a decrease of 30% in schistosomula viability, whilst treatment with NJ05+NJ07 lead to a reduction of 75% in viability measured by ATP quantitation and propidium iodide labeling. …”

Therapeutic administration of hMSCs failed to decrease pulmonary inflammation or modify BAL inflammatory cell counts in experimental severe influenza. by Ilyse Darwish (446378)

Small Molecule ErbB Inhibitors Decrease Proliferative Signaling and Promote Apoptosis in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia by Mary E. Irwin (293687)

“…This approach has improved clinical responses, but molecular remissions are seen in less than 50% of patients leaving few treatment options in the event of relapse. …”

Blood Pressure and LDL-C During Follow-up. by Karl Ingard (22582091)

“…The secondary endpoints were cardiovascular death, myocardial infarction, stroke, ischemic stroke, all-cause mortality, fracture, orthostatic hypotension, serious bleeding, and health-related quality of life. During a mean follow-up of 3.8 years, 31.7% (n = 64) of the patients in the intervention group and 37.5% (n = 72) in the control group reached the primary endpoint (HR 0.82, 95% CI 0.58–1.14, <i>P</i> = 0.23). …”

Baseline Characteristics of Included Patients. by Karl Ingard (22582091)

“…The secondary endpoints were cardiovascular death, myocardial infarction, stroke, ischemic stroke, all-cause mortality, fracture, orthostatic hypotension, serious bleeding, and health-related quality of life. During a mean follow-up of 3.8 years, 31.7% (n = 64) of the patients in the intervention group and 37.5% (n = 72) in the control group reached the primary endpoint (HR 0.82, 95% CI 0.58–1.14, <i>P</i> = 0.23). …”

DataSheet_1_Human surfactant protein A inhibits SARS-CoV-2 infectivity and alleviates lung injury in a mouse infection model.pdf by Ikechukwu B. Jacob (18253300)

“…Pre-incubation of SARS-CoV-2 (Delta) with human SP-A inhibited virus binding and entry and reduced viral load in human lung epithelial cells, evidenced by the dose-dependent decrease in viral RNA, nucleocapsid protein (NP), and titer (p<0.01). …”

Location of Aldabra Atoll. by Anna Koester (11805572)

CD4 T cell polyfunctionality inversely correlates with host susceptibility to <i>C</i>. <i>muridarum</i> in the FRT. by Miguel A. B. Mercado (17847533)

EGYVIR molecular mechanism as a virucidal and cytokine storm disturbance via NF-Kb pathway. by Wael H. Roshdy (9656689)

Targeted DNA demethylation in human cells by fusion of a plant 5-methylcytosine DNA glycosylase to a sequence-specific DNA binding domain by Jara Teresa Parrilla-Doblas (3825424)

“…In contrast, plants use specific DNA glycosylases that directly excise 5mC and initiate its substitution for unmethylated C in a base excision repair process. …”

Identification of small molecules that inhibit viral M mRNA nuclear export and/or decrease viral M mRNA levels. by Matthew Esparza (8661219)

“…<p>(<b>A</b>) Representative images showing uninfected cells; cells infected with A/WSN/33 and pretreated with 0.5% DMSO (control), which show viral M mRNA exported into the cytoplasm, in red; and cells infected with A/WSN/33 pre-treated with 2.5 μM of the transcription inhibitor DRB (5,6-dichloro-1-β-D-ribofuranosylbenzimidazole). …”

Frontier molecular orbitals (FMOs; optimized, HOMO, LUMO) pictures of two neighboring quaternary ammonium-based rings without (5) and with one (6a) or two (6b) alkyl chains and no... by Ghadeer Mubarak (21567569)

Image_5_Upregulated IL-6 Indicates a Poor COVID-19 Prognosis: A Call for Tocilizumab and Convalescent Plasma Treatment.TIF by Jian Wu (41301)

“…As a stable indicator, the changes in IL-6 levels could indicate the inflammatory conditions during a viral infection. …”