Desmosomal Cadherins Are Decreased in Explanted Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patient Hearts by Alexia Vite (462320)

“…Genetic studies have demonstrated the central role of desmosomal proteins in this disease, where 50% of patients harbor a mutation in a desmosmal gene. …”

nLTD decreases the molecular proximity between endogenous spine cofilin and F-actin by Barbara Calabrese (553229)

Table5_Effects of exercise modalities on decreased blood pressure in patients with hypertension.docx by Thiago Rozales Ramis (5311217)

Table3_Effects of exercise modalities on decreased blood pressure in patients with hypertension.docx by Thiago Rozales Ramis (5311217)

Table1_Effects of exercise modalities on decreased blood pressure in patients with hypertension.docx by Thiago Rozales Ramis (5311217)

Table4_Effects of exercise modalities on decreased blood pressure in patients with hypertension.docx by Thiago Rozales Ramis (5311217)

Table2_Effects of exercise modalities on decreased blood pressure in patients with hypertension.docx by Thiago Rozales Ramis (5311217)

Decrease in the portion of non-aggregated protein (γ_non-agg) in the course of DTT-induced aggregation of BSA (1 mg/ml) at 45°C. by Vera A. Borzova (456538)

Study flowchart. by Simon Lebek (9756148)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(B)</b> Bioluminescence recordings from the different conditions as depicted in <b>(A)</b>, the arrow indicates the time CO₂ was shifted from 5% to 1% (mean ± SE, <i>n</i> = 4 biological replicates per condition, AUC for 0 mM 0.34 ± 0.007, 1.59 ± 0.004 (<i>P</i> < 0.0001), 0.5 mM 1.00 ± 0.023, 2.68 ± 0.04 (<i>P</i> < 0.0001), 1 mM 1.66 ± 0.07, 3.34 ± 0.04 (<i>P</i> < 0.0001), 3 mM 2.06 ± 0.02, 2.79 ± 0.07 (<i>P</i> < 0.0001), 5 mM 2.02 ± 0.05, 2.43 ± 0.06 (<i>P</i> < 0.002), 7 mM 1.85 ± 0.01, 1.77 ± 0.02 (<i>P</i> < 0.02) two-sided Student’s <i>t</i> test). …”

Changes in lowland paddy soil fertility in the Philippines after 50 years of the Green Revolution by Atsushi Nakao (12396)

“…<p>The Green Revolution (GR) made a major contribution to increasing the rice yield in the Philippines from 1.3 t ha⁻¹ in 1966 to 4.0 t ha⁻¹ in 2018, but the changes in paddy soil fertility that occurred during this 50-year period remain unknown. We collected 37 soil samples from the plow layers of paddy fields in Luzon, Leyte, Panay, and Mindanao in the Philippines in 2016 and 2017 (the ‘2010s’) and compared their fertility-related soil properties with published data for soil samples collected from the same or nearby sampling sites in 1969 (the ‘1960s’). …”

Fig 3 - by Jialing He (2339845)

“…ICM was significantly associated with decreased risk of ischemic stroke (RR 0.76; 95% CI, 0.59–0.97; moderate-quality evidence) in patients with prior stroke and risk factors for stroke. …”

Summary of findings and strength of evidence. by Jialing He (2339845)

“…ICM was significantly associated with decreased risk of ischemic stroke (RR 0.76; 95% CI, 0.59–0.97; moderate-quality evidence) in patients with prior stroke and risk factors for stroke. …”

Fig 2 - by Jialing He (2339845)

“…ICM was significantly associated with decreased risk of ischemic stroke (RR 0.76; 95% CI, 0.59–0.97; moderate-quality evidence) in patients with prior stroke and risk factors for stroke. …”

Fig 1 - by Jialing He (2339845)

“…ICM was significantly associated with decreased risk of ischemic stroke (RR 0.76; 95% CI, 0.59–0.97; moderate-quality evidence) in patients with prior stroke and risk factors for stroke. …”

A. mCSM-PPI2 predicted ΔΔG is linearly correlated with SPR determined ACE2 variant Spike RBD affinities for ACE2 variants with negative predicted ΔΔG. by Stuart A. MacGowan (11326845)

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) by F. Anthony Romero (2452198)

“…Structure–activity relationship studies coupled with further structure-based design targeting the LPF shelf, BC loop, and KAc regions allowed us to significantly increase potency and selectivity, resulting in the identification of non-CNS penetrant <b>19</b> (GNE-781, TR-FRET IC₅₀ = 0.94 nM, BRET IC₅₀ = 6.2 nM; BRD4(1) IC₅₀ = 5100 nΜ) that maintained good in vivo PK properties in multiple species. …”

A savanna response to precipitation intensity by Ryan S. Berry (3913207)

Robust Operation of Mesoporous Antireflective Coatings under Variable Ambient Conditions by Barry Reid (1559488)

“…For high-surface-energy materials, pores on the 2–50 nm (i.e., on the subwavelength scale) are subject to capillary condensation by surrounding gas phase water molecules, which hampers their functioning. …”

FigShare_Data HbO2 JoP 50 (KMG).xlsx by Kayla Garvey (22027559)

“…High-altitude mice generally had greater aerobic capacity in hypoxia, in association with higher arterial O₂ saturation and lower P₅₀ (O₂ pressure at 50% Hb saturation) in most conditions. …”