Showing 11,601 - 11,620 results of 17,847 for search '(( 50 ((we decrease) OR (teer decrease)) ) OR ( 59 ((nn decrease) OR (a decrease)) ))', query time: 0.86s Refine Results
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    Visible-Light-Controlled Histone Deacetylase Inhibitors for Targeted Cancer Therapy by Laia Josa-Culleré (2736559)

    Published 2023
    “…Light-activatable drugs, whose activity can be precisely controlled with external light, could provide a more localized action of the drugs in the tumor, thus decreasing side effects and increasing efficacy. Herein, we introduce a series of photoswitchable azobenzene histone deacetylase inhibitors (HDACis) whose activity can be controlled by external visible light. …”
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    The effects of Mycobacterium tuberculosis on T cell responsiveness in granulomas by Jess Millar (620726)

    Published 2019
    “…At the cellular level, increased IFNγ concentrations are most sensitive to T cell levels between 30-40 days, while sensitivity of the binding threshold of MHCII peptide complexes that are required to activate T cells decreases in relation to T cell levels. Increased concentrations of Mtb antigens is most sensitive to granuloma size and infected macrophage, TNF-induced apoptosis rates from 25-50 days.…”
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    Repair-Mediated Duplication by Capture of Proximal Chromosomal DNA Has Shaped Vertebrate Genome Evolution by John K. Pace II (264178)

    Published 2009
    “…These events are thought to be a source of genomic instability and human diseases, but it is unclear whether they have contributed significantly to genome evolution. Here we developed an innovative computational pipeline that takes advantage of the repetitive structure of genomes to detect repair-mediated duplication events (RDs) that occurred in the germline and created insertions of at least 50 bp of genomic DNA. …”
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    Data_Sheet_1_The Paradoxical Leishmanicidal Effects of Superoxide Dismutase (SOD)-Mimetic Tempol in Leishmania braziliensis Infection in vitro.PDF by Laíse B. Oliveira (6880472)

    Published 2019
    “…Tempol surfaces as an interesting candidate for the chemotherapy of CL with an IC<sub>50</sub> of 0.66 ± 0.08 mM and selectivity index of 151. …”