Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease حسب Huashen Xu (13987046)

"…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC₅₀ = 0.1 nM, msEH IC₅₀ = 0.1 nM). …"

Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease حسب Huashen Xu (13987046)

"…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC₅₀ = 0.1 nM, msEH IC₅₀ = 0.1 nM). …"

Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease حسب Huashen Xu (13987046)

"…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC₅₀ = 0.1 nM, msEH IC₅₀ = 0.1 nM). …"

MBIC50 and MBEC50 values (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives against bacteria pathogen strains. حسب Jean Paul Dzoyem (6424445)

الموضوعات:

Differential gene expression assay EC₅₀ values in Huh-7 cells and PHH. حسب Xuan G. Luong (9761423)

Differential protective effects of a history of thyroid cancer on breast cancer-specific mortality in patients at age<50years and age≥50years at the diagnosis of breast cancer. حسب Weiwei Cheng (582223)

KDM6A mRNA expression is decreased in PTFE mice. حسب Simon Lebek (9756148)

Exercise test characteristics for identifying stenosis ≥ 50% in any limb among the 60 limbs with normal ABIs (> 0.91). حسب O. Stivalet (6890189)

Kylo-0603’s EC50 & tissue levels. حسب Xueqin lu (22250795)

Reference mutations versus background noise across replicates. حسب Lizhi Yu (12476136)

Analytical sensitivity and reproducibility. حسب Lizhi Yu (12476136)

Depth of coverage and heterogeneity of the mutation loci. x-axis, mutation loci in sample set one or two; y-axis, depth of coverage after UMI consolidation. حسب Lizhi Yu (12476136)

Quantification and accuracy of average VAF. حسب Lizhi Yu (12476136)

Schematic overview of the cross-platform study. حسب Lizhi Yu (12476136)

Impact of DNA extraction process on depth of coverage. حسب Lizhi Yu (12476136)

Downregulation of DOM decreases the abundance of PER and TIM. حسب Zhenxing Liu (399809)

"…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …"

FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma. حسب Laura L. Stafman (6577184)

"…There was a trend toward decreased Ki67 staining in FTY720-treated tumors (p = 0.29). …"

Nicotine decreased Wnt5a expressions in SK-BR-3 cells. حسب Masanori A. Murayama (5774585)

<b>Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decrease ISR activation in DRG neurons</b> حسب Muhammad Saad Yousuf (20745168)

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors حسب Stanislav Andreev (11067165)

"…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC₅₀ value of 6 nM). …"