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mean decrease » a decrease (Expand Search)
026 decrease » a decrease (Expand Search)
nn decrease » a decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
mean decrease » a decrease (Expand Search)
026 decrease » a decrease (Expand Search)
nn decrease » a decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…GCase activity measured by 4-MU in brain (A) measured as follows: WT 4mo 27.63±0.68, HOM 4mo 2.53±0.07, WT 8mo 27.65±0.69, HOM 8mo 3.01±0.20, WT 12 mo 27.49±0.46, HOM 12mo 3.15±0.26. GCase activity measured by 4-MU in liver (B) measured as follows: WT 4mo 93.69±7.16, HOM 4mo 3.90±0.21, WT 8mo 112.40±6.84, HOM 8mo 1.50±0.19, WT 12 mo 96.79±7.44, HOM 12mo 3.50±0.58. …”
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The decrease or inhibition of Hsp90 induced REST degradation.
Published 2019“…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. (E) The REST level decreased by GA more than 50% and (F) PU-H71 more than 80%, respectively. …”
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Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants
Published 2022“…A cocktail of etesevimab and JS026 increased neutralizing efficacy against both wild-type SARS-CoV-2 and the recent emergence of Alpha, Beta, Gamma, and Delta variants. …”
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Repetitive stress induces a decrease in sound-evoked activity.
Published 2025“…<p>(a) Left: noise-evoked activity rates at different noise intensities for chronically tracked PPys cells in baseline and repeated stress conditions (<i>N</i> = 5 mice, <i>n</i> = 285 neurons, mean ± SE). Activity rates decreased during repeated stress compared to baseline (2-way ANOVA, condition F = 185.6, <i>p</i> = 4.8 × 10<sup>−42</sup>, condition: intensity interaction F = 10.37, <i>p</i> = 9.3 × 10<sup>−21</sup>, nested ANOVA (mouse nested within session), condition F = 174, <i>p</i> = 1.5 × 10<sup>−39</sup>, condition: intensity interaction F = 12.7, <i>p</i> = 2 × 10<sup>−26</sup>, post hoc for each level baseline versus repetitive stress <i>p</i> < 0.01 for all levels above 50 dB, all Bonferroni corrected). …”
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Annual number of outpatient visits in all eyes.
Published 2025“…<p>Mean visit frequency (mean ± standard deviation) significantly decreased from 11.5 ± 4.3 preoperatively to 8.8 ± 4.1, 5.0 ± 3.4, and 4.4 ± 3.2 visits in the first, second, and third postoperative years, respectively (Kruskal–Wallis test, P < 0.001; Dunn’s test, **P < 0.01). …”
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